Abstract

Research Development Core: Susan Brooks, Director The goal of the RDC is to support an environment that promotes biological aging research by UM faculty scientists, through a combination of research retreats and pilot grant awards. The RDC will also begin, in July 2010, a program involving direct support of research programs of newly recruited junior faculty members, as suggested in the Nathan Shock Center RFA. Promoting collaboration between biogerontologists and experts in cognate fields is an important part of the RDC, and our research retreats are organized explicitly to attract the interest of local and visiting scholars who might not themselves be established in aging research. Pilot grants are targeted at scientists in the early stages of their faculty careers, but occasional awards may be made to mid-career researchers with a new interest in aging research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
2P30AG013283-16
Application #
8122841
Study Section
Special Emphasis Panel (ZAG1-ZIJ-2 (M1))
Project Start
2010-07-01
Project End
2015-06-30
Budget Start
2010-08-15
Budget End
2011-06-30
Support Year
16
Fiscal Year
2010
Total Cost
$155,638
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Xiong, Yi; Torsoni, Adriana Souza; Wu, Feihua et al. (2018) Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases. Elife 7:
Liu, Yan; Jiang, Lin; Sun, Chengxin et al. (2018) Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis. Nat Commun 9:2751
Ghosh, Amiya Kumar; Mau, Theresa; O'Brien, Martin et al. (2018) Novel role of autophagy-associated Pik3c3 gene in gonadal white adipose tissue browning in aged C57/Bl6 male mice. Aging (Albany NY) 10:764-774
Shen, Hong; Sheng, Liang; Xiong, Yi et al. (2017) Thymic NF-?B-inducing kinase regulates CD4+ T cell-elicited liver injury and fibrosis in mice. J Hepatol 67:100-109
Julius, Annabelle; Desai, Anjali; Yung, Raymond L (2017) Recombinant human erythropoietin stimulates melanoma tumor growth through activation of initiation factor eIF4E. Oncotarget 8:30317-30327
Kim, Evelyn H; Galchev, Vladimir I; Kim, Jin Young et al. (2016) Differential protein expression and basal lamina remodeling in human heart failure. Proteomics Clin Appl 10:585-96
Ghosh, Amiya Kumar; Mau, Theresa; O'Brien, Martin et al. (2016) Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue. Aging (Albany NY) 8:2525-2537
Feinstein, Lydia; Ferrando-Martínez, Sara; Leal, Manuel et al. (2016) Population Distributions of Thymic Function in Adults: Variation by Sociodemographic Characteristics and Health Status. Biodemography Soc Biol 62:208-21
Figueroa-Romero, Claudia; Hur, Junguk; Lunn, J Simon et al. (2016) Expression of microRNAs in human post-mortem amyotrophic lateral sclerosis spinal cords provides insight into disease mechanisms. Mol Cell Neurosci 71:34-45
Sharma, Naveen; Arias, Edward B; Cartee, Gregory D (2016) Inhibition of Akt2 phosphorylation abolishes the calorie restriction-induced improvement in insulin-stimulated glucose uptake by rat soleus muscle. Appl Physiol Nutr Metab 41:1208-1211

Showing the most recent 10 out of 219 publications