The overarching aim of the Program Development Core (PDC) is to provide pilot funding to support the development of innovative and ground-breaking research that will lead to a fuller understanding of the processes affecting population health at older ages and how these processes are faster or slower given biological, social, behavioral, psychological, economic, environmental, and health care conditions. Prior Center pilot projects have significantly increased our understanding of the roles of life circumstances, behaviors, stressors, biological factors, genetics in affecting health outcomes. These projects have also been highly successful in providing a basis for subsequent funded research and significant publications. In keeping with the overarching aim of the USC/UCLA Center on Biodemography and Population Health (CBPH), we devote a subset of our pilot projects to the development of innovations in biological and health measurement and data that provide increased resources for the entire research community. Our proposed pilots for the first year reflect the areas of CBPH focus: genetic/epigenetic processes;biological risk factors;international comparisons and the role of neighborhood or environmental characteristics. The PDC has also been an important mechanism for integrating and developing biodemographic researchers at our Universities including emerging scholars, new faculty, and faculty transitioning into biodemography. We have also supported pilot work from other universities that is critical to the further development of the field. The PDC is strongly integrated with the activities of the Administrative Research Core (ARC) and our Research Resources and Dissemination Core (RRDC). Some pilots produce work integrated into our national meetings organized by the ARC and some pilots either begin or transition to validation projects in the RRDC.

Public Health Relevance

The research supported by our Center attempts to clarify the biological pathways through which social, economic, and psychological and experiences impact health and how such influences may vary across subgroups and settings. This knowledge will increase our ability to improve health and reduce health disparities.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
2P30AG017265-15
Application #
8895518
Study Section
Special Emphasis Panel (ZAG1)
Program Officer
Haaga, John G
Project Start
Project End
Budget Start
2014-09-15
Budget End
2015-06-30
Support Year
15
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
DUNS #
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Mitchell, Uchechi A; Ailshire, Jennifer A; Brown, Lauren L et al. (2018) Education and Psychosocial Functioning Among Older Adults: 4-Year Change in Sense of Control and Hopelessness. J Gerontol B Psychol Sci Soc Sci 73:849-859
Stewart, Quincy Thomas; Cobb, Ryon J; Keith, Verna M (2018) The color of death: race, observed skin tone, and all-cause mortality in the United States. Ethn Health :1-23
Kim, Jung Ki; Ailshire, Jennifer A; Crimmins, Eileen M (2018) Twenty-year trends in cardiovascular risk among men and women in the United States. Aging Clin Exp Res :
Ross, Kharah M; Cole, Steve W; Carroll, Judith E et al. (2018) Elevated pro-inflammatory gene expression in the third trimester of pregnancy in mothers who experienced stressful life events. Brain Behav Immun :
Brown, Lauren L; Zhang, Yuan S; Mitchell, Colter et al. (2018) Does Telomere Length Indicate Biological, Physical, and Cognitive Health Among Older Adults? Evidence from the Health and Retirement Study. J Gerontol A Biol Sci Med Sci 73:1626-1632
Besser, Lilah M; Rodriguez, Daniel A; McDonald, Noreen et al. (2018) Neighborhood built environment and cognition in non-demented older adults: The Multi-Ethnic Study of Atherosclerosis. Soc Sci Med 200:27-35
Armer, Jessica S; Clevenger, Lauren; Davis, Lauren Z et al. (2018) Life stress as a risk factor for sustained anxiety and cortisol dysregulation during the first year of survivorship in ovarian cancer. Cancer 124:3401-3408
Black, David S; Cole, Steve W; Christodoulou, Georgia et al. (2018) Genomic mechanisms of fatigue in survivors of colorectal cancer. Cancer 124:2637-2644
Lutgendorf, Susan K; Thaker, Premal H; Arevalo, Jesusa M et al. (2018) Biobehavioral modulation of the exosome transcriptome in ovarian carcinoma. Cancer 124:580-586
Uchida, Yukiko; Kitayama, Shinobu; Akutsu, Satoshi et al. (2018) Optimism and the conserved transcriptional response to adversity. Health Psychol 37:1077-1080

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