Abstract

The goal of the Pilot/Exploratory Studies Core is to promote innovative multidisciplinary research related to mobility, balance and aging. The P/ESC manages the process of promotion, application, review, award and monitoring for Pilot/Exploratory Studies and Developmental projects. Priorities for awards include relevance to the OAIC theme, potential for independent funding, new multidisciplinary collaboration and translational potential. Additional priorities for Development Projects are potential to advance research methods in the area of mobility, balance and aging, degree of innovation and potential for incorporation into OAIC future studies. In order to make the most efficient use of resources, projects that serve as add-ons to existing funded studies are encouraged. Proposed first year pilot studies include PES-i: Role of NF-kB in stem cells in aging, PES-2: Pre-operative treatment with electrical stimulation enhances aged muscle regenerative capacity and return to functional mobility post-operatively, PES-3 Investigation into the Mechanisms of Symptom Relief with Forward Flexion in Older Patients with Spinal Stenosis and PES-4:Variability, Stability and Smoothness of Walking.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG024827-07
Application #
8124939
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2010-09-01
Budget End
2011-08-31
Support Year
7
Fiscal Year
2010
Total Cost
$85,480
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Rosso, Andrea L; Bohnen, Nicolaas I; Launer, Lenore J et al. (2018) Vascular and dopaminergic contributors to mild parkinsonian signs in older adults. Neurology 90:e223-e229
Agimi, Yll; Albert, Steven M; Youk, Ada O et al. (2018) Mandatory Physician Reporting of At-Risk Drivers: The Older Driver Example. Gerontologist 58:578-587
Bon, Jessica; Zhang, Yingze; Leader, Joseph K et al. (2018) Radiographic Emphysema, Circulating Bone Biomarkers, and Progressive Bone Mineral Density Loss in Smokers. Ann Am Thorac Soc 15:615-621
Best, John R; Liu-Ambrose, Teresa; Metti, Andrea L et al. (2018) Longitudinal Associations Between Walking Speed and Amount of Self-reported Time Spent Walking Over a 9-Year Period in Older Women and Men. J Gerontol A Biol Sci Med Sci 73:1265-1271
Yuan, Jian-Min; Beckman, Kenneth B; Wang, Renwei et al. (2018) Leukocyte telomere length in relation to risk of lung adenocarcinoma incidence: Findings from the Singapore Chinese Health Study. Int J Cancer 142:2234-2243
Metti, Andrea L; Best, John R; Shaaban, C Elizabeth et al. (2018) Longitudinal changes in physical function and physical activity in older adults. Age Ageing :
Sparto, Patrick J; Newman, A B; Simonsick, E M et al. (2018) Contributions to lateral balance control in ambulatory older adults. Aging Clin Exp Res 30:633-641
Hayden, Kathleen M; Baker, Laura D; Bray, George et al. (2018) Long-term impact of intensive lifestyle intervention on cognitive function assessed with the National Institutes of Health Toolbox: The Look AHEAD study. Alzheimers Dement (Amst) 10:41-48
Urbanek, Jacek K; Zipunnikov, Vadim; Harris, Tamara et al. (2018) Prediction of sustained harmonic walking in the free-living environment using raw accelerometry data. Physiol Meas 39:02NT02
Lee, Sei J; Larson, Eric B; Dublin, Sascha et al. (2018) A Cohort Study of Healthcare Utilization in Older Adults with Undiagnosed Dementia. J Gen Intern Med 33:13-15

Showing the most recent 10 out of 1292 publications