(BDMRC3) The UTMB OAIC Biostatistics and Data Management Resource Core 3 (BDMRC3) provides biostatistical support, collaboration and training, and develops novel biostatistic and data management tools for research relevant to the UTMB OAIC theme which is Translate pathways of functional loss and gain into interventions to optimize functional recovery in diverse geriatric populations. Since its establishment as a new OAIC Resource Core in 2014, the BDMRC3 has rapidly developed strong working relationships with OAIC investigators, and supported six Scholars, 17 OAIC pilot/developmental projects, six NIH R and K grants, three T32, one F30, two large AHRQ grants, and a Texas CPRIT center grant. It has produced 54 publications.
Specific aims of the BDMRC3 are: 1. Collaborate as investigators for OAIC projects with focus on improving physical function and recovery in older adults. The projects include pilot studies, developmental projects, and externally funded research; 2. Train Research Education Core (REC) scholars in biostatistics and data management to help them plan, conduct, and interpret results of their investigations in aging; 3. Enhance research information system infrastructure to assist in the procurement, management, and processing of data collected from extant databases; 4. Develop novel biostatistics methods and visual analytic applications for aging research. The significance of BCMRC3 for the UTMB OAIC is related to four main tasks. 1) Expanding the data infrastructure to consolidate and harmonize measurements across OAIC projects and data sources, enhance accessibility in the use of EHR data for multiple OAIC projects, and share available sources of data with the UTMB RCMAR and UTMB P2C; 2) BCMRC3 personnel collectively operates as a key resource for design, analysis, and interpretation in OAIC projects; 3) BCMRC3 faculty mentors REC scholars, leading to long-term collaborations and more effective research development; and 4) BCMRC3 members develop and adapt novel analytical methods to improve the validity and utility of results stemming from OAIC research.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
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Special Emphasis Panel (ZAG1)
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University of Texas Med Br Galveston
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Saenz, Joseph L; Downer, Brian; Garcia, Marc A et al. (2018) Cognition and Context: Rural-Urban Differences in Cognitive Aging Among Older Mexican Adults. J Aging Health 30:965-986
Smith, Theresa M; Pappadis, Monique R; Krishnan, Shilpa et al. (2018) Stroke Survivor and Caregiver Perspectives on Post-Stroke Visual Concerns and Long-Term Consequences. Behav Neurol 2018:1463429
Middleton, Addie; Downer, Brian; Haas, Allen et al. (2018) Functional Status Is Associated With 30-Day Potentially Preventable Readmissions Following Skilled Nursing Facility Discharge Among Medicare Beneficiaries. J Am Med Dir Assoc 19:348-354.e4
Downer, Brian; Al Snih, Soham; Howrey, Bret T et al. (2018) Combined effects of cognitive impairment and pre-frailty on future frailty and death in older Mexican Americans. Aging Ment Health :1-8
Goodwin, James S; Salameh, Habeeb; Zhou, Jie et al. (2018) Association of Hospitalist Years of Experience With Mortality in the Hospitalized Medicare Population. JAMA Intern Med 178:196-203
Salinas, Jennifer J; Gonzalez, Jennifer M Reingle; Al Snih, Soham (2018) Type 2 diabetes, depressive symptoms and disability over a 15-year follow-up period in older Mexican Americans living in the southwestern United States. J Diabetes Complications 32:75-82
Hong, Ickpyo; Karmarkar, Amol; Chan, Winston et al. (2018) Discharge Patterns for Ischemic and Hemorrhagic Stroke Patients Going From Acute Care Hospitals to Inpatient and Skilled Nursing Rehabilitation. Am J Phys Med Rehabil 97:636-645
Jamadar, Sharna D; Sforazzini, Francesco; Raniga, Parnesh et al. (2018) Sexual Dimorphism of Resting-State Network Connectivity in Healthy Ageing. J Gerontol B Psychol Sci Soc Sci :
McNeil, John J; Woods, Robyn L; Nelson, Mark R et al. (2018) Effect of Aspirin on Disability-free Survival in the Healthy Elderly. N Engl J Med 379:1499-1508
Asghar, Rabia; Chondronikola, Maria; Dillon, Edgar L et al. (2018) Quantification of muscle triglyceride synthesis rate requires an adjustment for total triglyceride content. J Lipid Res 59:2018-2024

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