(BDMRC3) The UTMB OAIC Biostatistics and Data Management Resource Core 3 (BDMRC3) provides biostatistical support, collaboration and training, and develops novel biostatistic and data management tools for research relevant to the UTMB OAIC theme which is Translate pathways of functional loss and gain into interventions to optimize functional recovery in diverse geriatric populations. Since its establishment as a new OAIC Resource Core in 2014, the BDMRC3 has rapidly developed strong working relationships with OAIC investigators, and supported six Scholars, 17 OAIC pilot/developmental projects, six NIH R and K grants, three T32, one F30, two large AHRQ grants, and a Texas CPRIT center grant. It has produced 54 publications.
Specific aims of the BDMRC3 are: 1. Collaborate as investigators for OAIC projects with focus on improving physical function and recovery in older adults. The projects include pilot studies, developmental projects, and externally funded research; 2. Train Research Education Core (REC) scholars in biostatistics and data management to help them plan, conduct, and interpret results of their investigations in aging; 3. Enhance research information system infrastructure to assist in the procurement, management, and processing of data collected from extant databases; 4. Develop novel biostatistics methods and visual analytic applications for aging research. The significance of BCMRC3 for the UTMB OAIC is related to four main tasks. 1) Expanding the data infrastructure to consolidate and harmonize measurements across OAIC projects and data sources, enhance accessibility in the use of EHR data for multiple OAIC projects, and share available sources of data with the UTMB RCMAR and UTMB P2C; 2) BCMRC3 personnel collectively operates as a key resource for design, analysis, and interpretation in OAIC projects; 3) BCMRC3 faculty mentors REC scholars, leading to long-term collaborations and more effective research development; and 4) BCMRC3 members develop and adapt novel analytical methods to improve the validity and utility of results stemming from OAIC research.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
2P30AG024832-16
Application #
10027669
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
16
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Texas Med Br Galveston
Department
Type
DUNS #
800771149
City
Galveston
State
TX
Country
United States
Zip Code
77555
Collins, Diane M; Downer, Brian; Kumar, Amit et al. (2018) Impact of Multiple Chronic Conditions on Activity Limitations Among Older Mexican-American Care Recipients. Prev Chronic Dis 15:E51
Moro, Tatiana; Brightwell, Camille R; Deer, Rachel R et al. (2018) Muscle Protein Anabolic Resistance to Essential Amino Acids Does Not Occur in Healthy Older Adults Before or After Resistance Exercise Training. J Nutr 148:900-909
Ryan, Joanne; Woods, Robyn L; Britt, Carlene et al. (2018) Normative performance of healthy older individuals on the Modified Mini-Mental State (3MS) examination according to ethno-racial group, gender, age, and education level. Clin Neuropsychol :1-19
Volpi, Elena (2018) Is leucine content in dietary protein the key to muscle preservation in older women? Am J Clin Nutr 107:143-144
Valderrama-Hinds, Luis M; Al Snih, Soham; Chen, Nai-Wei et al. (2018) Falls in Mexican older adults aged 60 years and older. Aging Clin Exp Res 30:1345-1351
Raji, Mukaila A; Kuo, Yong-Fang; Adhikari, Deepak et al. (2018) Decline in opioid prescribing after federal rescheduling of hydrocodone products. Pharmacoepidemiol Drug Saf 27:513-519
McNeil, John J; Nelson, Mark R; Woods, Robyn L et al. (2018) Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. N Engl J Med 379:1519-1528
Middleton, Addie; Kuo, Yong-Fang; Graham, James E et al. (2018) Readmission Patterns Over 90-Day Episodes of Care Among Medicare Fee-for-Service Beneficiaries Discharged to Post-acute Care. J Am Med Dir Assoc 19:896-901
Bhasin, Shalender; Gill, Thomas M; Reuben, David B et al. (2018) Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE): A Cluster-Randomized Pragmatic Trial of a Multifactorial Fall Injury Prevention Strategy: Design and Methods. J Gerontol A Biol Sci Med Sci 73:1053-1061
Iqbal, Fatima; Durham, William J; Melhem, Ayyash et al. (2018) Sex-dependent difference in the relationship between adipose-tissue cholesterol efflux and estradiol concentrations in young healthy humans. Int J Dev Neurosci 64:59-62

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