The goal of the Research Career Development Core (RCD Core) is to recruit, train, mentor, and develop future research leaders with skills in translational research and clinical investigation directed at exploring approaches to understand and modify multiple pathways of functional decline. Previous experience with our OAlC-supported Research Development Core has taught us that we must aggressively recruit, select, mentor and train promising junior faculty to enter the field of aging research. Promising scientists will be recruited to develop and/or expand their investigative skills with an emphasis on translating basic research findings into clinical studies or, taking clinical research findings and posing new basic research questions. RCDC Scholars will take courses tailored to their specific career needs, receive mentoring from their senior faculty team, and receive leadership training to prepare them for key positions in geriatrics and gerontology. Our mentoring plan is designed to motivate clinical investigators to explore basic research principles and basic scientists to interface with clinical researchers. The RCD Core will ensure that its awardees take advantage of other OAIC research cores and other experienced investigators at Duke University Medical Center. RCD Core awardees will participate in OAIC seminars and conferences where interdisciplinary investigators discuss their work In this milieu ideas for collaborations are started and discussed, resulting in new projects and lines of inquiry. For each junior faculty member chosen as an RCDC Scholar the Duke Pepper OAlC's intended outcome is to prepare and support them to become independent investigators doing aging research. After two to three years of support, success for each RCDC Scholar will be measured by their ability to secure research career development support or independent investigator- Initiated extramural funding. RCD Core Project Leader, Kenneth Lyles, MD will work especially closely with Pilot /Exploratory Core Studies Core Project Leader, Kenneth Schmader, MD, to maximize the use of our Core's resources to help prepare our awardees so they have the requisite skills as well as pilot data to successfully complete for career-development awards, and when appropriate investigator-initiated funding. As occurred over the previous 19 years, with previous Pepper GRTC and OAIC support, the RCD Core will produce talented, well-trained investigators to help lead the next generation of scientists in the field of aging directed at positively clinical, translational or basic research that focuses on exploring multiple approaches to understanding and modifying multiple pathways of functional decline.

Public Health Relevance

This Research Career Development Core in the Duke Pepper OAIC has the knowledge, skills, faculty, operations staff and resources necessary to recruit, select, mentor and train the next cadre of clinical, translational and basic investigators critically needed in this country who will be capable of conducting research to maintain or restore independence in older persons.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
2P30AG028716-06
Application #
8205990
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8 (M1))
Project Start
Project End
Budget Start
2011-09-01
Budget End
2012-06-30
Support Year
6
Fiscal Year
2011
Total Cost
$24,351
Indirect Cost
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Zeng, Yi; Nie, Chao; Min, Junxia et al. (2018) Sex Differences in Genetic Associations With Longevity. JAMA Netw Open 1:
Huang, Z Y; Perry, E; Huebner, J L et al. (2018) Biomarkers of inflammation - LBP and TLR- predict progression of knee osteoarthritis in the DOXY clinical trial. Osteoarthritis Cartilage 26:1658-1665
Blay, Sergio L; Fillenbaum, Gerda G; Mello, Marcelo F et al. (2018) 12-month prevalence and concomitants of DSM-IV depression and anxiety disorders in two violence-prone cities in Brazil. J Affect Disord 232:204-211
Hall, Rasheeda K; Luciano, Alison; Pieper, Carl et al. (2018) Association of Kidney Disease Quality of Life (KDQOL-36) with mortality and hospitalization in older adults receiving hemodialysis. BMC Nephrol 19:11
Golightly, Yvonne M; Hannan, Marian T; Nelson, Amanda E et al. (2018) Relationship of Joint Hypermobility with Ankle and Foot Radiographic Osteoarthritis and Symptoms in a Community-Based Cohort. Arthritis Care Res (Hoboken) :
Pavon, Juliessa M; Sloane, Richard J; Pieper, Carl F et al. (2018) Poor Adherence to Risk Stratification Guidelines Results in Overuse of Venous Thromboembolism Prophylaxis in Hospitalized Older Adults. J Hosp Med 13:403-404
Toles, Mark; Leeman, Jennifer; Colón-Emeric, Cathleen et al. (2018) Implementing a Standardized Transition Care Plan in Skilled Nursing Facilities. J Appl Gerontol :733464818783689
Hall, Rasheeda K; Sloane, Richard; Pieper, Carl et al. (2018) Competing Risks of Fracture and Death in Older Adults with Chronic Kidney Disease. J Am Geriatr Soc 66:532-538
Devinney, Michael J; Mathew, Joseph P; Berger, Miles (2018) Postoperative Delirium and Postoperative Cognitive Dysfunction: Two Sides of the Same Coin? Anesthesiology 129:389-391
Cary Jr, Michael P; Hall, Rasheeda K; Anderson, Amber L et al. (2018) Management Team Perceptions of Risks and Strategies for Preventing Falls Among Short-Stay Patients in Nursing Homes. Health Care Manag (Frederick) 37:76-85

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