The Biostatistics Core (RC3) is one of the four resource cores in the Claude D. Pepper Older Americans Independence Center (OAIC) at the University of Florida (UF). The mission of the UF OAIC is twofold: 1) to enhance late-life health and independence through interdisciplinary approaches to optimize physical performance and mobility, and 2) to train new investigators in research on aging and disability, while developing their leadership qualities. The RC3 is a key cog in the interaction among scientists from diverse disciplines to accomplish this mission. It provides research-design and statistical-analysis resources and helps construct data-collection forms and manage the data (including providing quality control) for both preclinical and clinical studies conducted within the OAIC. The RC3 is involved in all phases of the OAIC studies: initial pre-proposal study design and sample-size calculations, randomization, and state-of-the-art statistical analyses once the data are collected. It also helps prepare manuscripts for dissemination within the research community. In addition, the RC3 serves as a key resource to OAIC junior faculty and Junior Scholars, providing consulting services and periodic special-interest training topics, such as research design, power analysis, data management, study implementation and management, and statistical methodology and analyses. Finally, for OAIC studies where the existing biostatistical methodologies are inadequate, the RC3 has assembled strong expertise for developing new biostatistical methods and data-management tools beyond current practice. The RC3 will develop new methodology for adaptive design of clinical trials and simultaneous statistical inference. This will provide customized support that meets the demands of the OAIC's research design and statistical analyses.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG028740-13
Application #
9690526
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2019-04-01
Budget End
2020-03-31
Support Year
13
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Florida
Department
Type
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Chatterjee, Sudeshna A; Daly, Janis J; Porges, Eric C et al. (2018) Mobility Function and Recovery After Stroke: Preliminary Insights From Sympathetic Nervous System Activity. J Neurol Phys Ther 42:224-232
Iqbal, Atif; Sakharuk, Ilya; Goldstein, Lindsey et al. (2018) Readmission After Elective Ileostomy in Colorectal Surgery Is Predictable. JSLS 22:
Bryant, Andrew J; Shenoy, Vinayak; Fu, Chunhua et al. (2018) Myeloid-derived Suppressor Cells Are Necessary for Development of Pulmonary Hypertension. Am J Respir Cell Mol Biol 58:170-180
Cote, Isabelle; Toklu, Hale Z; Green, Sara M et al. (2018) Limiting feeding to the active phase reduces blood pressure without the necessity of caloric reduction or fat mass loss. Am J Physiol Regul Integr Comp Physiol 315:R751-R758
Zhang, Bi; Gong, Jianke; Zhang, Wenyuan et al. (2018) Brain-gut communications via distinct neuroendocrine signals bidirectionally regulate longevity in C. elegans. Genes Dev 32:258-270
Ebner, Natalie C; Luedicke, Joerg; Voelkle, Manuel C et al. (2018) An Adult Developmental Approach to Perceived Facial Attractiveness and Distinctiveness. Front Psychol 9:561
Kumar, Ashok; Rani, Asha; Scheinert, Rachel B et al. (2018) Nonsteroidal anti-inflammatory drug, indomethacin improves spatial memory and NMDA receptor function in aged animals. Neurobiol Aging 70:184-193
Callahan, Kathryn E; Lovato, Laura; Miller, Michael E et al. (2018) Self-Reported Physical Function As a Predictor of Hospitalization in the Lifestyle Interventions and Independence for Elders Study. J Am Geriatr Soc 66:1927-1933
Snyder, Peter J; Bhasin, Shalender; Cunningham, Glenn R et al. (2018) Lessons From the Testosterone Trials. Endocr Rev 39:369-386
Anton, Stephen D; Moehl, Keelin; Donahoo, William T et al. (2018) Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting. Obesity (Silver Spring) 26:254-268

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