The mission of the UM-OAIC is to determine and evaluate the mechanisms and efficacy of motor learning based exercise rehabilitation that focuses on the restoration and maintenance of function, and the prevention of the functional decline that puts older adults with chronic diseases at risk for disability. This will be accomplished by 1) conducting basic and clinical translational research that examines the mechanisms underlying the functional impairments associated with prevalent diseases in older people across the domains of neuromotor, muscular, metabolic and cardiovascular function;2) translating these findings from the lab to the clinic to design novel efficacious motor learning based exercise interv/entions for community implementation;3) supporting PES, DPs and externally funded grants examining the mechanisms underlying disability, the processes of recovery and the restoration and maintenance of function and 4) fostering the career development of junior faculty from multiple disciplines into independent geriatric academic scientists through mentor- based research training, Research Cores in Biostatistics, Informatics and Translational Research, Applied Physiology and Tissue Mechanisms, and Mobility Function and Neuromotor Plasticity collaborate in Research Working Groups (RWGs) which will guide studies from inception to publication and through to community translation. The RCDC provides mentor-based training with didactic courses to promote the career development of RCDC Scholars;a PESC proposes 5 novel interventions;and a novel RC3 DP examines mechanisms by which balance training reduces fall risk. The UM-OAIC multidisciplinary research team has the skills and motivation to change clinical rehabilitation practice by developing innovative, motor learning based exercise rehabilitation programs that will improve the functional and clinical outcomes of older people with disabilities to promote independent living. We are optimistic that the UMOAlC's translational approach to geriatrics and rehabilitation research will change clinical practice by developing innovative, feasible rehabilitation interventions that will promote the functional independence and the health of older Americans.

Public Health Relevance

The increased life expectancy of older Americans makes the maintenance of functional independence a major public health priority. The UM-OAIC's outstanding environment for research and research training in geriatrics and rehabilitation sciences will optimize motor learning based exercise rehabilitation treatments to reduce the morbidity and disability associated with chronic disease to prevent functional declines and to maintain functional independence.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG028747-08
Application #
8513206
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8 (M1))
Program Officer
Eldadah, Basil A
Project Start
2006-07-01
Project End
2016-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
8
Fiscal Year
2013
Total Cost
$946,833
Indirect Cost
$314,406
Name
University of Maryland Baltimore
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
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Beaupre, Lauren A; Wai, Eugene K; Hoover, Donald R et al. (2018) A comparison of outcomes between Canada and the United States in patients recovering from hip fracture repair: secondary analysis of the FOCUS trial. Int J Qual Health Care 30:97-103
Rathbun, Alan M; Shardell, Michelle D; Stuart, Elizabeth A et al. (2018) Persistence of depressive symptoms and gait speed recovery in older adults after hip fracture. Int J Geriatr Psychiatry 33:875-882
Oursler, Krisann K; Sorkin, John D; Ryan, Alice S et al. (2018) A pilot randomized aerobic exercise trial in older HIV-infected men: Insights into strategies for successful aging with HIV. PLoS One 13:e0198855
Verceles, Avelino C; Bhatti, Waqas (2018) The Ethical Concerns of Seeking Consent from Critically Ill, Mechanically Ventilated Patients for Research - A Matter of Possessing Capacity or Surrogate Insight. Clin Ethics 13:107-111
Leiter, Nikita; Motta, Melissa; Reed, Robert M et al. (2018) Numeracy and Interpretation of Prognostic Estimates in Intracerebral Hemorrhage Among Surrogate Decision Makers in the Neurologic ICU. Crit Care Med 46:264-271

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