Abstract

The Center for AIDS Research at NYU Medical Center comprises seventy clinical and basic science investigators performing research in four contiguous institutions in lower Manhattan. These scientists are all faculty members of the NYU School of Medicine, although their laboratories and research clinics are located at the Manhattan VA Hospital, BelleVue Hospital, the Public Research Institute, as well as the School of Medicine buildings, including Tisch Hospital and the Skirball Institute. Many important contributions to our understanding of the virology, immunology, epidemiology, and the infections and neoplastic complications of this disease have been made by NY investigators since they identified their first patient in 1980. NYU clinicians are caring for over 4,000 HIV-infected individuals, and our clinical research efforts attract additional patients from several thousands of HIV+ subjects throughout the metropolitan region. The CFAR supports this productive program of research and increases its efficiency by providing four shared core facilities, and developmental funds to support young investigators and new research opportunities. The CFAR also brings together investigators with similar interests into several research programs to facilitate innovation and collaboration.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027742-15
Application #
6770039
Study Section
Special Emphasis Panel (ZAI1-EWS-A (J1))
Program Officer
Young, Janet M
Project Start
1989-09-01
Project End
2005-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
15
Fiscal Year
2004
Total Cost
$1,625,620
Indirect Cost

  Institution

Name
New York University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016

  Publications

Gornalusse, German G; Mummidi, Srinivas; Gaitan, Alvaro A et al. (2015) Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor. Proc Natl Acad Sci U S A 112:E4762-71
Miller, Elizabeth A; Gopal, Ramya; Valdes, Vanessa et al. (2015) Soluble CD40 ligand contributes to dendritic cell-mediated T-cell dysfunction in HIV-1 infection. AIDS 29:1287-96
Weiden, Michael D; Hoshino, Satomi; Levy, David N et al. (2014) Adenosine deaminase acting on RNA-1 (ADAR1) inhibits HIV-1 replication in human alveolar macrophages. PLoS One 9:e108476
Ryndak, Michelle B; Singh, Krishna K; Peng, Zhengyu et al. (2014) Transcriptional profiling of Mycobacterium tuberculosis replicating ex vivo in blood from HIV- and HIV+ subjects. PLoS One 9:e94939
Phelan, Joan A; Abrams, William R; Norman, Robert G et al. (2014) Design aspects of a case-control clinical investigation of the effect of HIV on oral and gastrointestinal soluble innate factors and microbes. PLoS One 9:e112901
Sivapalasingam, Sumathi; Mendillo, Megan; Ahmed, Aabid et al. (2014) The importance of caregivers in the outcome of pediatric HIV management, Mombasa, Kenya. AIDS Care 26:425-33
Weiser, Keren; Barton, Meredith; Gershoony, Dafna et al. (2013) HIV's Nef interacts with ?-catenin of the Wnt signaling pathway in HEK293 cells. PLoS One 8:e77865
O'Brien, Meagan; Montenont, Emilie; Hu, Liang et al. (2013) Aspirin attenuates platelet activation and immune activation in HIV-1-infected subjects on antiretroviral therapy: a pilot study. J Acquir Immune Defic Syndr 63:280-8
Rich, Josiah D; DiClemente, Ralph; Levy, Judith et al. (2013) Correctional facilities as partners in reducing HIV disparities. J Acquir Immune Defic Syndr 63 Suppl 1:S49-53
Alvarez, Yelina; Tuen, Michael; Nàdas, Arthur et al. (2012) In vitro restoration of Th17 response during HIV infection with an antiretroviral drug and Th17 differentiation cytokines. AIDS Res Hum Retroviruses 28:823-34

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