The proposed UW CFAR is organized around 6 core units: Administration (including information transfer/publications and research training); clinical and molecular retrovirology; immunology, clinical research; biostatistics and epidemiology (including International AIDS Research and AIDS Registry); and non- human primate research. Two additional core units, behavioral sciences research and radiological imaging research, are envisioned via separate funding in future years. Over 75 faculty staff investigators of the proposed CFAR participate in active or pending research grants directly related to AIDS, HIV, or SIV and many of these also have other active grants in closely related fields such as non-primate retrovirology, molecular/cellular immunology, and other STDs. Ten distinct AIDS related themes have been identified, many involving parallel research in humans and non-human primates. The proposed CFAR would help coordinate this research to ensure efficient use of primates in research most relevant to human infection. Six active and two pending institutional post-doctoral research or clinical training grants at the UW are AIDS related. The process of planning this proposal has helped to coordinate the new allocations of 7450 sq. ft. of lab space to basic research on HIV and SIV. The CFAR would fund alteration, renovation, and equipping of a portion of these labs on the UW campus and at Fred Hutchinson Cancer Research Center. Planning for relocation of the HMC AIDS Clinic and the NIAID ACTU is already funded and underway. The CFAR would fund creation and co-location of a CFAR Clinical Research unit, including clinical and epidemiologic research trainees at the same site as the AIDS clinic and ACTU.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (SRC (41))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Washington
Schools of Medicine
United States
Zip Code
Pyra, Maria; Brown, Elizabeth R; Haberer, Jessica E et al. (2018) Patterns of Oral PrEP Adherence and HIV Risk Among Eastern African Women in HIV Serodiscordant Partnerships. AIDS Behav :
Jiang, Wei; Luo, Zhenwu; Martin, Lisa et al. (2018) Drug Use is Associated with Anti-CD4 IgG-mediated CD4+ T Cell Death and Poor CD4+ T Cell Recovery in Viral-suppressive HIV-infected Individuals Under Antiretroviral Therapy. Curr HIV Res 16:143-150
Edwards, Jessie K; Cole, Stephen R; Moore, Richard D et al. (2018) Sensitivity Analyses for Misclassification of Cause of Death in the Parametric G-Formula. Am J Epidemiol :
LaCourse, Sylvia M; Cranmer, Lisa M; Bekker, Adrie et al. (2018) Symptom screening for active tuberculosis in pregnant women living with HIV. Cochrane Database Syst Rev 2018:
Merlin, Jessica S; Long, Dustin; Becker, William C et al. (2018) Brief Report: The Association of Chronic Pain and Long-Term Opioid Therapy With HIV Treatment Outcomes. J Acquir Immune Defic Syndr 79:77-82
Wagner, Anjuli D; O?Malley, Gabrielle; Firdawsi, Olivia et al. (2018) Brief Report: Disclosure, Consent, Opportunity Costs, and Inaccurate Risk Assessment Deter Pediatric HIV Testing: A Mixed-Methods Study. J Acquir Immune Defic Syndr 77:393-399
Golovaty, Ilya; Sharma, Monisha; Van Heerden, Alastair et al. (2018) Cost of Integrating Noncommunicable Disease Screening Into Home-Based HIV Testing and Counseling in South Africa. J Acquir Immune Defic Syndr 78:522-526
LaCourse, Sylvia M; Cranmer, Lisa M; Njuguna, Irene N et al. (2018) Urine Tuberculosis Lipoarabinomannan Predicts Mortality in Hospitalized Human Immunodeficiency Virus-Infected Children. Clin Infect Dis 66:1798-1801
Altekruse, Sean F; Shiels, Meredith S; Modur, Sharada P et al. (2018) Cancer burden attributable to cigarette smoking among HIV-infected people in North America. AIDS 32:513-521
Torres, Thiago S; Harrison, Linda J; La Rosa, Alberto M et al. (2018) Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women. AIDS 32:583-593

Showing the most recent 10 out of 1275 publications