Globally, the burden of HIV disproportionately impacts developing countries. Women are particularly affected, representing 60% of HIV infections in the Sub-Saharan region1. There are favorable trends in HIV incidence in some countries, but considerable obstacles to controlling the disease persist. Current UW CFAR-affiliated research efforts including male circumcision, herpes suppression, microbicides and vaccine trials continue to contribute promising prevention techniques. Maximizing research capacity in resourcelimited settings requires ongoing support of infrastructure, human resources, technical training, and community engagement"""""""". Since its inception in 1995, the UW CFAR International Clinical and Prevention Research Core has worked to address these gaps and to promote effective HIV research in a global context. UW CFAR priority countries include Kenya and Peru. We also support CFAR-affiliated investigators working in Central America, Senegal, Mozambique, Uganda, China, India and the Caribbean. Currently, more than 78 UW CFARaffiliated faculty and fellows and 41 international investigators are actively involved in international research and training activities. The Center for AIDS Research, part of the wider UW Center for AIDS and STD, is a WHO/PAHO Collaborating Center for AIDS and STD. Mission: The UW CFAR International Core supports, facilitates and coordinates research on HIV/AIDS by University of Washington faculty in developing countries by providing research mentorship, logistical, operational and infrastructure support as well as small pilot grants. The Long-Term Goals of the International Core are to: Promote and facilitate HIV/AIDS research by UW CFAR-affiliated investigators in developing countries. Develop long-term, sustainable partnerships for HIV research and training in a focused set of developing country settings, enabling collaborating investigators and institutions in those countries to achieve greater independence with responsibilities and roles equivalent to those of the UW-based CFAR-affiliated faculty and institutions. Support innovative HIV/AIDS research in women and children in developing countries.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027757-23
Application #
8080965
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
23
Fiscal Year
2010
Total Cost
$206,685
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Wilson, Kate S; Wanje, George; Masese, Linnet et al. (2018) A Prospective Cohort Study of Fertility Desire, Unprotected Sex, and Detectable Viral Load in HIV-Positive Female Sex Workers in Mombasa, Kenya. J Acquir Immune Defic Syndr 78:276-282
Bengtson, Angela M; Pence, Brian W; Eaton, Ellen F et al. (2018) Patterns of efavirenz use as first-line antiretroviral therapy in the United States: 1999-2015. Antivir Ther 23:363-372
Fredericksen, Rob J; Mayer, Kenneth H; Gibbons, Laura E et al. (2018) Development and Content Validation of a Patient-Reported Sexual Risk Measure for Use in Primary Care. J Gen Intern Med 33:1661-1668
Gómez, Laurén A; Crowell, Claudia S; Njuguna, Irene et al. (2018) Improved Neurodevelopment After Initiation of Antiretroviral Therapy in Human Immunodeficiency Virus-infected Children. Pediatr Infect Dis J 37:916-922
Ikoma, Minako; Gantt, Soren; Casper, Corey et al. (2018) KSHV oral shedding and plasma viremia result in significant changes in the extracellular tumorigenic miRNA expression profile in individuals infected with the malaria parasite. PLoS One 13:e0192659
Grover, Surbhi; Desir, Fidel; Jing, Yuezhou et al. (2018) Reduced Cancer Survival Among Adults With HIV and AIDS-Defining Illnesses Despite No Difference in Cancer Stage at Diagnosis. J Acquir Immune Defic Syndr 79:421-429
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Thomson, Kerry A; Dhanireddy, Shireesha; Andrasik, Michele et al. (2018) Fertility desires and preferences for safer conception strategies among people receiving care for HIV at a publicly-funded clinic in Seattle, WA. AIDS Care 30:121-129
Lohman-Payne, Barbara; Gabriel, Benjamin; Park, Sangshin et al. (2018) HIV-exposed uninfected infants: elevated cord blood Interleukin 8 (IL-8) is significantly associated with maternal HIV infection and systemic IL-8 in a Kenyan cohort. Clin Transl Med 7:26
Ronen, Keshet; Unger, Jennifer A; Drake, Alison L et al. (2018) SMS messaging to improve ART adherence: perspectives of pregnant HIV-infected women in Kenya on HIV-related message content. AIDS Care 30:500-505

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