Adolescents, both in the US and globally, are a key population affected by HIV, and novel research strategies are needed to prevent, treat, and potentially cure HIV in this vulnerable group. The primary purpose of the Adolescent Health Scientific Working Group (SWG) is to catalyze innovative research by bringing together investigators with interest and experience in addressing the unique issues facing adolescents in HIV treatment, cure, and prevention, including development of biomedical HIV prevention approaches, optimized models for care and treatment, and relevant behavioral and laboratory science. First, we will initiate a monthly research work-in-progress group, to create a peer network and collaborative space for investigation and discovery pertaining to adolescent health and HIV, which will enable scientific mentoring and access to CFAR resources, including the Behavioral Science, Implementation Science, and Developmental Cores, and eHealth SWG. This will efficiently facilitate investigators to develop novel research programs and collaborations pertaining to adolescent health and to access trainee support and funds (Aim 1). Second, by holding skill-building workshops, we will fill gaps in members' knowledge of current methods for adolescent HIV research, and link investigators to timely and innovative approaches to conducting research with adolescents. Our multidisciplinary workshops will incorporate topics related to adolescent medicine, behavioral science, implementation science, and laboratory methods, and will build institutional expertise in novel methodological approaches to HIV research involving adolescents (Aim 2). Third, we will stimulate institutional interest and enthusiasm for the topic of adolescent health and HIV by hosting global leaders in this field as visiting scholars in Seattle (Aim 3). We will disseminate invitations to participate in all activities to CFAR consortium partners, as well as local partners such as the Bill and Melinda Gates Foundation and to our international partners, which will enable circulation of ideas and approaches on defeating HIV among adolescents, creating relevant synergies for both global and domestic HIV research. These comprehensive activities will enable our CFAR members to develop robust research in adolescent HIV prevention and treatment, with cross-disciplinary approaches and multiple institutional collaborations. This SWG will advance HIV science by highlighting research strategies and topics specific to adolescents that are currently under development by HIV researchers and others; SWG researchers will benefit from multiple venues to share experiences and learn from one another. By designing a SWG that focuses on adolescent health, we will ensure that CFAR researchers have opportunities to establish strong collaborations to work with this vulnerable population and promote the adoption of an adolescent-focused research agenda. Our unique strengths in both domestic and global HIV research will allow us to connect adolescent research in both arenas to cross-pollinate ideas, strategies and best practices.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI027757-31
Application #
9534846
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2018-06-01
Budget End
2019-05-31
Support Year
31
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Pyra, Maria; Brown, Elizabeth R; Haberer, Jessica E et al. (2018) Patterns of Oral PrEP Adherence and HIV Risk Among Eastern African Women in HIV Serodiscordant Partnerships. AIDS Behav :
Jiang, Wei; Luo, Zhenwu; Martin, Lisa et al. (2018) Drug Use is Associated with Anti-CD4 IgG-mediated CD4+ T Cell Death and Poor CD4+ T Cell Recovery in Viral-suppressive HIV-infected Individuals Under Antiretroviral Therapy. Curr HIV Res 16:143-150
Edwards, Jessie K; Cole, Stephen R; Moore, Richard D et al. (2018) Sensitivity Analyses for Misclassification of Cause of Death in the Parametric G-Formula. Am J Epidemiol :
LaCourse, Sylvia M; Cranmer, Lisa M; Bekker, Adrie et al. (2018) Symptom screening for active tuberculosis in pregnant women living with HIV. Cochrane Database Syst Rev 2018:
Merlin, Jessica S; Long, Dustin; Becker, William C et al. (2018) Brief Report: The Association of Chronic Pain and Long-Term Opioid Therapy With HIV Treatment Outcomes. J Acquir Immune Defic Syndr 79:77-82
Wagner, Anjuli D; O?Malley, Gabrielle; Firdawsi, Olivia et al. (2018) Brief Report: Disclosure, Consent, Opportunity Costs, and Inaccurate Risk Assessment Deter Pediatric HIV Testing: A Mixed-Methods Study. J Acquir Immune Defic Syndr 77:393-399
Golovaty, Ilya; Sharma, Monisha; Van Heerden, Alastair et al. (2018) Cost of Integrating Noncommunicable Disease Screening Into Home-Based HIV Testing and Counseling in South Africa. J Acquir Immune Defic Syndr 78:522-526
LaCourse, Sylvia M; Cranmer, Lisa M; Njuguna, Irene N et al. (2018) Urine Tuberculosis Lipoarabinomannan Predicts Mortality in Hospitalized Human Immunodeficiency Virus-Infected Children. Clin Infect Dis 66:1798-1801
Altekruse, Sean F; Shiels, Meredith S; Modur, Sharada P et al. (2018) Cancer burden attributable to cigarette smoking among HIV-infected people in North America. AIDS 32:513-521
Torres, Thiago S; Harrison, Linda J; La Rosa, Alberto M et al. (2018) Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women. AIDS 32:583-593

Showing the most recent 10 out of 1275 publications