Adolescents, both in the US and globally, are a key population affected by HIV, and novel research strategies are needed to prevent, treat, and potentially cure HIV in this vulnerable group. The primary purpose of the Adolescent Health Scientific Working Group (SWG) is to catalyze innovative research by bringing together investigators with interest and experience in addressing the unique issues facing adolescents in HIV treatment, cure, and prevention, including development of biomedical HIV prevention approaches, optimized models for care and treatment, and relevant behavioral and laboratory science. First, we will initiate a monthly research work-in-progress group, to create a peer network and collaborative space for investigation and discovery pertaining to adolescent health and HIV, which will enable scientific mentoring and access to CFAR resources, including the Behavioral Science, Implementation Science, and Developmental Cores, and eHealth SWG. This will efficiently facilitate investigators to develop novel research programs and collaborations pertaining to adolescent health and to access trainee support and funds (Aim 1). Second, by holding skill-building workshops, we will fill gaps in members' knowledge of current methods for adolescent HIV research, and link investigators to timely and innovative approaches to conducting research with adolescents. Our multidisciplinary workshops will incorporate topics related to adolescent medicine, behavioral science, implementation science, and laboratory methods, and will build institutional expertise in novel methodological approaches to HIV research involving adolescents (Aim 2). Third, we will stimulate institutional interest and enthusiasm for the topic of adolescent health and HIV by hosting global leaders in this field as visiting scholars in Seattle (Aim 3). We will disseminate invitations to participate in all activities to CFAR consortium partners, as well as local partners such as the Bill and Melinda Gates Foundation and to our international partners, which will enable circulation of ideas and approaches on defeating HIV among adolescents, creating relevant synergies for both global and domestic HIV research. These comprehensive activities will enable our CFAR members to develop robust research in adolescent HIV prevention and treatment, with cross-disciplinary approaches and multiple institutional collaborations. This SWG will advance HIV science by highlighting research strategies and topics specific to adolescents that are currently under development by HIV researchers and others; SWG researchers will benefit from multiple venues to share experiences and learn from one another. By designing a SWG that focuses on adolescent health, we will ensure that CFAR researchers have opportunities to establish strong collaborations to work with this vulnerable population and promote the adoption of an adolescent-focused research agenda. Our unique strengths in both domestic and global HIV research will allow us to connect adolescent research in both arenas to cross-pollinate ideas, strategies and best practices.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
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Special Emphasis Panel (ZAI1)
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University of Washington
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Torres, Thiago S; Harrison, Linda J; La Rosa, Alberto M et al. (2018) Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women. AIDS 32:583-593
Altekruse, Sean F; Shiels, Meredith S; Modur, Sharada P et al. (2018) Cancer burden attributable to cigarette smoking among HIV-infected people in North America. AIDS 32:513-521
Patel, Rena C; Bukusi, Elizabeth A; Baeten, Jared M (2018) Current and future contraceptive options for women living with HIV. Expert Opin Pharmacother 19:1-12
Ross, Jennifer M; Ying, Roger; Celum, Connie L et al. (2018) Modeling HIV disease progression and transmission at population-level: The potential impact of modifying disease progression in HIV treatment programs. Epidemics 23:34-41
Wagner, Anjuli D; Shah, Seema K; Njuguna, Irene N et al. (2018) Financial Incentives to Motivate Pediatric HIV Testing-Assessing the Potential for Coercion, Inducement, and Voluntariness. J Acquir Immune Defic Syndr 78:e15-e18
Stekler, Joanne D; Milne, Ross; Payant, Rachel et al. (2018) Transmission of HIV-1 drug resistance mutations within partner-pairs: A cross-sectional study of a primary HIV infection cohort. PLoS Med 15:e1002537
Smith, Robert A; Wu, Vincent H; Zavala, Christopher G et al. (2018) In Vitro Antiviral Activity of Cabotegravir against HIV-2. Antimicrob Agents Chemother 62:
Stekler, Joanne D; Violette, Lauren R; Niemann, Lisa et al. (2018) Repeated False-Positive HIV Test Results in a Patient Taking HIV Pre-Exposure Prophylaxis. Open Forum Infect Dis 5:ofy197
Golob, Jonathan L; Stern, Joshua; Holte, Sarah et al. (2018) HIV DNA levels and decay in a cohort of 111 long-term virally suppressed patients. AIDS 32:2113-2118
Katz, David A; Golden, Matthew R; Hughes, James P et al. (2018) HIV Self-Testing Increases HIV Testing Frequency in High-Risk Men Who Have Sex With Men: A Randomized Controlled Trial. J Acquir Immune Defic Syndr 78:505-512

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