Abstract

The Clinical Virology Core Laboratory is intended to represent an integral component of UCSF Center for AIDS Research (CFAR) by providing state-of-the-art resources to the local community of HIV researchers for: To ensure the facilities and equipment to perform state-of-the-art virologic evaluations of clinical samples. To provide expertise, facilities, and assistance for the isolation and propagation of IV from clinical samples. To provide expertise, facilities and assistance for the quantitative determination of viral burden extant in clinical samples. To maintain and further develop methods to evaluate the sensitivity of HIV isolates to experimental antiviral agents. To continue to develop and disseminate virologic methods for the detailed investigation of the natural history and treatment of HIV infection. To continue intralaboratory QC/QA standards and procedures. Given the close intellectual and physical relationship of the proposed CFAR Core Facilities, we expect that the synergistic interactions that have emerged over the past two years will continue to flourish.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027763-09
Application #
6234918
Study Section
Project Start
1997-03-01
Project End
1998-02-28
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
9
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Streubel, Gundula; Watson, Ariane; Jammula, Sri Ganesh et al. (2018) The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells. Mol Cell 70:371-379.e5
Dunkley, Emma; Ashaba, Scholastic; Burns, Bridget et al. (2018) ""I beg you…breastfeed the baby, things changed"": infant feeding experiences among Ugandan mothers living with HIV in the context of evolving guidelines to prevent postnatal transmission. BMC Public Health 18:188
Cary, Daniele C; Peterlin, B Matija (2018) Natural Products and HIV/AIDS. AIDS Res Hum Retroviruses 34:31-38
Carrico, Adam W; G?mez, Walter; Jain, Jennifer et al. (2018) Randomized controlled trial of a positive affect intervention for methamphetamine users. Drug Alcohol Depend 192:8-15
Holmes, Charles B; Sikazwe, Izukanji; Sikombe, Kombatende et al. (2018) Estimated mortality on HIV treatment among active patients and patients lost to follow-up in 4 provinces of Zambia: Findings from a multistage sampling-based survey. PLoS Med 15:e1002489
Buggert, Marcus; Nguyen, Son; Salgado-Montes de Oca, Gonzalo et al. (2018) Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue. Sci Immunol 3:
Buggert, Marcus; Nguyen, Son; McLane, Laura M et al. (2018) Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease. PLoS Pathog 14:e1006973
Freeman, Esther E; Semeere, Aggrey; Osman, Hany et al. (2018) Smartphone confocal microscopy for imaging cellular structures in human skin in vivo. Biomed Opt Express 9:1906-1915
Martin, Jeremy W; Chen, Joseph C; Neidleman, Jason et al. (2018) Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. Biol Reprod 99:336-348
Joglekar, Alok V; Liu, Zhe; Weber, Jeffrey K et al. (2018) T cell receptors for the HIV KK10 epitope from patients with differential immunologic control are functionally indistinguishable. Proc Natl Acad Sci U S A 115:1877-1882

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