The aims of the UCSF-GIVI CFAR are to support a multi-disciplinary environment that promotes basic, clinical, epidemiologic, behavioral, and translational research in the prevention, detection, and treatment of HIV infection and AIDS and to further the programs of NIH institutes by providing unique and effectively managed activities propelling HIV research. CFAR applies effective leadership, open communications, educational opportunities, sound resource management, and strategic planning to link CFAR members across sites and scientific disciplines. The Center's leadership is committed to proactive management, transparency and continued program monitoring, evaluation, and readjustment. CFAR maintains an effective partnership with the UCSF AIDS Research Institute and with the Center for AIDS Prevention Studies. To catalyze multidisciplinary research, the Center manages six scientific cores (Clinical and Population Sciences, Immunology, Virology, Specimen Banking, Pharmacology, and International). The Clinical and Population Sciences Core facilitates access to appropriate clinical cohorts. The International Core, focused on a growing portfolio in Uganda, will build in-country capacity and collaborate with the Fogarty International Center in training. Expansion to other African sites is expected. Core Directors are charged with member outreach and soliciting new investigators to take advantage of the cutting edge technologies and assays available within the cores. Success of the scientific cores is assessed by the quality of the multidisciplinary science they stimulate and by the publications and successful grants to which they contribute. The CFAR Administrative Core maintains an electronic network, including videoconferencing, to connect and inform all CFAR members, organizes scientific seminars and symposia, and implements financial systems to monitor and report all CFAR funds, ensuring maximum CFAR effectiveness. The Developmental Core funds pilot and basic science grants. It supports the next generation of HIV science through mentored pilot grants and an extremely successful and ambitious formal mentoring program. The success of the UCSF-GIVI CFAR is evident in the scientific accomplishments of its investigators, its ability to galvanize fundamentally new science through its focus on innovative multidisciplinary HIV research, and the significant institutional support it receives from UCSF, the San Francisco Veterans Affairs Medical Center and the J. David Gladstone Institutes. ? ? ? CORE A: Administrative (Volberding, Paul) ? ? CORE A DESCRIPTION (provided by applicant): The Administrative Core provides the scientific leadership and governance, educational and collaborative opportunities, resource management and strategic and implementation activities that allow CFAR scientists to achieve their scientific potential through productive, multidisciplinary collaborations.
The specific aims of the Administrative Core are to: ? ? 1. Provide scientific leadership and governance that reflects the scientific and geographic diversity of HIV research in San Francisco ? ? 2. Provide all CFAR members with educational and collaborative opportunities that encourage and facilitate collaborative, cross-disciplinary investigations ? ? 3. Provide effective resource management to allow the most effective and efficient use of resources to support Core services and other programs ? ? 4. Conduct regular, ongoing strategic planning and program evaluation; and solicit internal and external advice on Center operations. The Administrative Core has established an organizational structure and an array of services that enhance the ability of CFAR scientists to conduct significant, innovative translational HIV research in support of the CFAR mission. ? ? The Administrative Core achieves its specific aims through frequent and regular meetings of the CFAR leaders, administrators and advisory groups, and by producing a variety of educational opportunities for CFAR members including a University-wide seminar series and annual scientific symposia to facilitate collaborative science and to mitigate the challenges of the several locations of member's research in San Francisco and abroad. The Core communicates with members via email and other means to announce seminars, symposia and other educational and scientific events. The Core has also developed a highly effective financial management system that enables the CFAR leadership to closely monitor CFAR funds and other resources, and to reallocate monies to support high-priority research initiatives identified through strategic planning, thereby ensuring that CFAR resources are used to maximum benefit. To ensure the overall effectiveness of the UCSF-GIVI CFAR, the Core coordinates an ongoing internal and external evaluation process through quarterly planning sessions and annual strategic planning that involve CFAR leadership, investigators and staff, and an annual review by an External Advisory Committee composed of nationally recognized scientists and clinicians. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI027763-16
Application #
7252926
Study Section
Special Emphasis Panel (ZAI1-EC-A (J1))
Program Officer
Namkung, Ann S
Project Start
1997-03-01
Project End
2012-08-31
Budget Start
2007-09-15
Budget End
2008-08-31
Support Year
16
Fiscal Year
2007
Total Cost
$3,190,101
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Cohen, Stephanie E; Sachdev, Darpun; Lee, Sulggi A et al. (2018) Acquisition of tenofovir-susceptible, emtricitabine-resistant HIV despite high adherence to daily pre-exposure prophylaxis: a case report. Lancet HIV :
Altekruse, Sean F; Shiels, Meredith S; Modur, Sharada P et al. (2018) Cancer burden attributable to cigarette smoking among HIV-infected people in North America. AIDS 32:513-521
Ferdin, Jana; Gori?ar, Katja; Dolžan, Vita et al. (2018) Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA. PLoS One 13:e0191613
Faust, Tyler B; Li, Yang; Bacon, Curtis W et al. (2018) The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. Elife 7:
Wong, Cherise; Gange, Stephen J; Moore, Richard D et al. (2018) Multimorbidity Among Persons Living with Human Immunodeficiency Virus in the United States. Clin Infect Dis 66:1230-1238
Coleman, Sharon M; Gnatienko, Natalia; Lloyd-Travaglini, Christine A et al. (2018) False-positive HIV diagnoses: lessons from Ugandan and Russian research cohorts. HIV Clin Trials 19:15-22
Dubé, Karine; Gianella, Sara; Concha-Garcia, Susan et al. (2018) Ethical considerations for HIV cure-related research at the end of life. BMC Med Ethics 19:83
Libby, Ashley Rg; Joy, David A; So, Po-Lin et al. (2018) Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference. Elife 7:
Haas, Andreas D; Zaniewski, Elizabeth; Anderegg, Nanina et al. (2018) Retention and mortality on antiretroviral therapy in sub-Saharan Africa: collaborative analyses of HIV treatment programmes. J Int AIDS Soc 21:
Jin, Harry; Ogunbajo, Adedotun; Mimiaga, Matthew J et al. (2018) Over the influence: The HIV care continuum among methamphetamine-using men who have sex with men. Drug Alcohol Depend 192:125-128

Showing the most recent 10 out of 1541 publications