Core - Developmental Core

Abstract

The UCLA CFAR Developmental Core is designed to complement traditional sources of funding from government and private sources by providing rapid review for innovative and sometimes risky projects for relatively modest amounts of funding. We have also prioritized a number of areas for support, including clinical/basic science collaborations, transnational research and evolving areas of research. Funds are also requested for support of new investigators for AIDS-related activities.
The Specific Aims for the Developmental Core are: 1. To provide a mechanism for concise application and rapid review of high-quality innovative basic science projects. 2. To provide a mechanism for rapid response to evolving areas of AIDS research which require immediate action. 3. To provide a mechanism for funding of """"""""transnational"""""""" projects to further develop promising therapeutic compounds which arise through basic science studies. 4. To promote high-quality projects which involve collaborations between basic and clinical areas of study. 5. To provide funding for new faculty at UCLA engaged in AIDS research, and for recruitment of a new investigator(s) to AIDS-related areas at UCLA that are under-represented.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Center Core Grants (P30)
• Project #: 5P30AI028697-08
• Application #: 2823652
• Budget Start: 1997-10-01
• Budget End: 1998-09-30
• Support Year: 8
• Fiscal Year: 1998

Institution

• Name: University of California Los Angeles
• DUNS #: 119132785
• City: Los Angeles
• State: CA
• Country: United States
• Zip Code: 90095

Publications

Seang, Sophie; Kelesidis, Theodoros; Huynh, Diana et al. (2018) Low Levels of Endothelial Progenitor Cells and Their Association with Systemic Inflammation and Monocyte Activation in Older HIV-Infected Men. AIDS Res Hum Retroviruses 34:39-45

Kojima, Noah; Klausner, Jeffrey D (2018) Fight Fire With Fire: Innovations to Address Syphilis Among Men Who Have Sex With Men. Sex Transm Dis 45:e85-e86

Black, David S; Cole, Steve W; Christodoulou, Georgia et al. (2018) Genomic mechanisms of fatigue in survivors of colorectal cancer. Cancer 124:2637-2644

Ziyad, Safiyyah; Riordan, Jesse D; Cavanaugh, Ann M et al. (2018) A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis. Cell Rep 22:1211-1224

Walser, Tonya C; Jing, Zhe; Tran, Linh M et al. (2018) Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells. Cancer Res 78:1986-1999

Fulcher, Jennifer A; Shoptaw, Steven; Makgoeng, Solomon B et al. (2018) Brief Report: Recent Methamphetamine Use Is Associated With Increased Rectal Mucosal Inflammatory Cytokines, Regardless of HIV-1 Serostatus. J Acquir Immune Defic Syndr 78:119-123

Chua, Bernadette Anne; Ngo, Jamie Ann; Situ, Kathy et al. (2018) Protein S and Gas6 induce efferocytosis of HIV-1-infected cells. Virology 515:176-190

Kojima, Noah; Klausner, Jeffrey D (2018) Improving management of sexually transmitted infections in those who use pre-exposure prophylaxis for human immunodeficiency virus infection. AIDS 32:272-275

Khamaikawin, Wannisa; Shimizu, Saki; Kamata, Masakazu et al. (2018) Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1. Mol Ther Methods Clin Dev 9:23-32

Allyn, P R; O'Malley, S M; Ferguson, J et al. (2018) Attitudes and potential barriers towards hepatitis C treatment in patients with and without HIV coinfection. Int J STD AIDS 29:334-340