Abstract

The Immunology (Flow Cytometry, Immune Function) Core Facility of the CFAR will provide state-of-the-art technology and expertise for members of the Center and for developmental users. Our goals are to provide flow cytometric expertise to include training, preparation of samples, and analysis for users of the Core. In addition, we will develop the Immune Function part of the Core to perform mitogenesis, cytokine, and cytotoxic assay for users approved by the Internal Advisory Committee. Our intent is to improve and enhance interactions between AIDS researchers at Baylor College of Medicine and to provide expertise for users who might otherwise encounter difficulties in their HIV-related programs. We are in a unique position to offer these services and have a long track record of successful core facility operation and collaborations with AIDS investigators throughout the Texas Medical Center.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI036211-02
Application #
3727710
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Baylor College of Medicine
Department
Type
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Tan, Qiumin; Brunetti, Lorenzo; Rousseaux, Maxime W C et al. (2018) Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma. Proc Natl Acad Sci U S A 115:E1511-E1519
Bayrer, James R; Wang, Hongtao; Nattiv, Roy et al. (2018) LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. Nat Commun 9:4055
Bui, Thanh Cong; Scheurer, Michael E; Pham, Vy Thi-Tuong et al. (2018) Intravaginal practices and genital human papillomavirus infection among female sex workers in Cambodia. J Med Virol 90:1765-1774
Kim, Myunghoo; Galan, Carolina; Hill, Andrea A et al. (2018) Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses. Immunity 49:151-163.e5
Martini-Stoica, Heidi; Cole, Allysa L; Swartzlander, Daniel B et al. (2018) TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading. J Exp Med 215:2355-2377
Kogiso, Mari; Qi, Lin; Braun, Frank K et al. (2018) Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models. Clin Cancer Res 24:2159-2170
Xiao, Yangyan; de Paiva, Cintia S; Yu, Zhiyuan et al. (2018) Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells. Int Immunol 30:457-470
Yosef, Nejla; Vadakkan, Tegy J; Park, June-Hee et al. (2018) The phenotypic and functional properties of mouse yolk-sac-derived embryonic macrophages. Dev Biol 442:138-154
Kho, Jordan; Tian, Xiaoyu; Wong, Wing-Tak et al. (2018) Argininosuccinate Lyase Deficiency Causes an Endothelial-Dependent Form of Hypertension. Am J Hum Genet 103:276-287
Grzeskowiak, Caitlin L; Kundu, Samrat T; Mo, Xiulei et al. (2018) In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer. Nat Commun 9:2732

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