The purpose of the AIDS-Related Malignancy Core is to develop infrastructure to foster and support AIDS-related malignancy (ARM) research at Baylor.
The specific aims of the core are: (1) To provide leadership and mechanisms to foster collaborations and encourage ARM research at Baylor; (2) To provide assistance, facilities, and expertise for sample acquisition, processing, storage, and assay; and (3) To facilitate access to the Tulane Regional Primate Research Center. There are a number of investigators engaged in cancer research at Baylor, but few efforts are focused on ARM because of lack of needed infrastructure. Communication among interested faculty members will be enhanced by a CFAR Research Working Group on AIDS-related malignancies. Sources of specimens for ARM studies are being arr'anged by collaborative agreements. One such collaboration has been established with Prof. C. Arion, Bucharest, to study malignancies of childhood, including in HIVinfected Romanian children. A dedicated laboratory is under construction to handle ARM clinical specimens. The core is also engaged in assay development to ensure that difficult-to-obtain ARM specimens are handled optimally to yield high-quality data. The Core Director is Janet S. Butel, Ph.D., whose research background is in tumor virology and cancer biology. She will be assisted by a Core Oversight Committee. Louis N. Martin, Ph.D. is the liaison at the Tulane Regional Primate Research Center to whom requests to access resources and services of the primate center will be communicated.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
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Special Emphasis Panel (ZAI1)
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Baylor College of Medicine
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Newton, Jared M; Hanoteau, Aurelie; Sikora, Andrew G (2018) Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors. J Vis Exp :
Wang, Changjun; Zaheer, Mahira; Bian, Fang et al. (2018) Sjögren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice. Int J Mol Sci 19:
Spencer, Jennifer L; Lahon, Anismrita; Tran, Linda L et al. (2018) Replication of Zika Virus in Human Prostate Cells: A Potential Source of Sexually Transmitted Virus. J Infect Dis 217:538-547
Hong, M J; Gu, B H; Madison, M C et al. (2018) Protective role of ?? T cells in cigarette smoke and influenza infection. Mucosal Immunol 11:894-908
Madan, Simran; Kron, Bettina; Jin, Zixue et al. (2018) Arginase overexpression in neurons and its effect on traumatic brain injury. Mol Genet Metab 125:112-117
Hsu, Joanne I; Dayaram, Tajhal; Tovy, Ayala et al. (2018) PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy. Cell Stem Cell 23:700-713.e6
Misra, Anisha; Gleeson, Emile; Wang, Weiming et al. (2018) Glycosyl-Phosphatidylinositol-Anchored Anti-HIV Env Single-Chain Variable Fragments Interfere with HIV-1 Env Processing and Viral Infectivity. J Virol 92:
Byrd, Tiara T; Fousek, Kristen; Pignata, Antonella et al. (2018) TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer. Cancer Res 78:489-500
Nabekura, Tsukasa; Chen, Zhiying; Schroeder, Casey et al. (2018) Crk Adaptor Proteins Regulate NK Cell Expansion and Differentiation during Mouse Cytomegalovirus Infection. J Immunol 200:3420-3428
Haller, Meade; Au, Jason; O'Neill, Marisol et al. (2018) 16p11.2 transcription factor MAZ is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A 115:E1849-E1858

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