Abstract

The Behavioral Sciences Core (BSC) was added with the 2005 renewal application. The BSC was developed following a needs analysis by the CFAR and in response to member surveys in 2003 and 2004. It is based on strong capabilities of The University of Texas Health Science Center at Houston (UTHouston) in applying behavioral sciences to HIV/AIDS research, complemented by the strong clinical and basic sciences that exist at Baylor College of Medicine and UTHouston. The Core is led by Dr. R.M. Grimes and is housed at The University of Texas Health Science Center at Houston. The objectives of the Core are: (1) To facilitate behavioral science research in HIV/AIDS prevention and care, and (2) To integrate behavioral sciences into clinical and basic HIV/AIDS research studies. These objectives are accomplished by providing expertise in services utilized by behavioral scientists and by making these readily available to clinicians and basic researchers who want to include a behavioral component to their studies. Core services include providing expertise in study design, facilitating questionnaire development, and the design and interpretation of qualitative studies. The Core has been highly successful in encouraging HIV/AIDS research that includes a behavioral component. The Core also places a high priority on its support of interdisciplinary studies proposed by CFAR leadership that target research in areas that represent gaps at our CFAR and that encourage new interactions among CFAR cores and CFAR members at Baylor and UTHouston.

Public Health Relevance

The Center for AIDS Research (CFAR) at Baylor-UTHouston supports research on the pathogenesis, prevention, detection, and treatment of HIV infection and AIDS. The CFAR has been an essential catalyst for HIV/AIDS research in the Houston area. The State of Texas ranks fourth in the total number of AIDS cases in the United States. The Behavioral Sciences Core provides help in designing questionnaires and in the interpretation of studies of behavior associated with HIV and AIDS.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI036211-18
Application #
8382344
Study Section
Special Emphasis Panel (ZAI1-JBS-A)
Project Start
Project End
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
18
Fiscal Year
2012
Total Cost
$115,683
Indirect Cost
$31,884

  Institution

Name
Baylor College of Medicine
Department
Type
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Tan, Qiumin; Brunetti, Lorenzo; Rousseaux, Maxime W C et al. (2018) Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma. Proc Natl Acad Sci U S A 115:E1511-E1519
Bayrer, James R; Wang, Hongtao; Nattiv, Roy et al. (2018) LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. Nat Commun 9:4055
Bui, Thanh Cong; Scheurer, Michael E; Pham, Vy Thi-Tuong et al. (2018) Intravaginal practices and genital human papillomavirus infection among female sex workers in Cambodia. J Med Virol 90:1765-1774
Kim, Myunghoo; Galan, Carolina; Hill, Andrea A et al. (2018) Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses. Immunity 49:151-163.e5
Martini-Stoica, Heidi; Cole, Allysa L; Swartzlander, Daniel B et al. (2018) TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading. J Exp Med 215:2355-2377
Kogiso, Mari; Qi, Lin; Braun, Frank K et al. (2018) Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models. Clin Cancer Res 24:2159-2170
Xiao, Yangyan; de Paiva, Cintia S; Yu, Zhiyuan et al. (2018) Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells. Int Immunol 30:457-470
Yosef, Nejla; Vadakkan, Tegy J; Park, June-Hee et al. (2018) The phenotypic and functional properties of mouse yolk-sac-derived embryonic macrophages. Dev Biol 442:138-154
Kho, Jordan; Tian, Xiaoyu; Wong, Wing-Tak et al. (2018) Argininosuccinate Lyase Deficiency Causes an Endothelial-Dependent Form of Hypertension. Am J Hum Genet 103:276-287
Grzeskowiak, Caitlin L; Kundu, Samrat T; Mo, Xiulei et al. (2018) In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer. Nat Commun 9:2732

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