Overview - The UCSD Center for AIDS Research (CFAR) engages, synergizes and serves investigators at UCSD (including the Veterans Medical Research Foundation of the San Diego VA Healthcare System), The Scripps Research Institute, the Salk Institute, and the La Jolla Institute for Allergy and Immunology. Since 1994, the CFAR has enhanced HIV/AIDS activities at the participating institutions and the San Diego community by 1) encouraging young faculty and investigators new to HIV/AIDS research through Developmental Grant Awards;2) providing expert advice and services in a number of specialized research areas through the CFAR Cores, and 3) fostering research interactions and community wide education through mentoring, training. Scientific Focus Groups, education, and outreach programs.
The specific aims of the UCSD CFAR are to a) provide development and implementation of innovative HIV research and the foundation and framework for highly productive collaborations across disciplines, investigators, and our four member institutions, b) provide training, inspiration, mentoring, and expert guidance (TIME) to trainees and junior and international investigators, c) create scientific cores that extend the scientific reach of CFAR investigators, d) capitalize on our international expertise, proximity to Mexico and MEPI programs to create locally sustainable HIV research programs in targeted resource limited settings, e) foster collaborations across CFARs for NIH-funded programs and initiatives, and f) develop a strategic plan for the growth of the CFAR and to flexibly adapt to a constantly evolving research environment. Since our renewal in 2007, these efforts are yielding a productive, enthusiastic and growing group of investigators. As the synergy between our investigators and member institutions increases, we have identified the need to expand our infrastructure to address new and expanding opportunities. We have added new faculty members and expanded scientific interactions with local institutions. The revised and improved CFAR is comprised of nine Cores: Administrative, Developmental, Flow Cytometry, Genomics and Sequencing, Clinical Investigation and Biostatistics, Protein Expression and Proteomics, International, Translational Virology, and Bioinformatics and Information Technologies. We continue to be guided by our External Advisory and Executive Committees, as well as the CFAR Director and Co-Directors, Core Directors, Scientific Focus Groups and our membership.

Public Health Relevance

The UCSD CFAR supports basic, clinical and translational research programs at UCSD and at our member institutions. In addition to our active, productive and groundbreaking research, we have a remarkable program for fostering the development of junior faculty and investigators new to HIV research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI036214-19A1
Application #
8490495
Study Section
Special Emphasis Panel (ZAI1-UKS-A (J1))
Program Officer
Namkung, Ann S
Project Start
1994-04-01
Project End
2018-03-31
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
19
Fiscal Year
2013
Total Cost
$3,083,697
Indirect Cost
$496,271
Name
University of California San Diego
Department
Pathology
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Fraser, Hannah; Zibbell, Jon; Hoerger, Thomas et al. (2018) Scaling-up HCV prevention and treatment interventions in rural United States-model projections for tackling an increasing epidemic. Addiction 113:173-182
Dinesha, T R; Boobalan, J; Sivamalar, S et al. (2018) Occult HBV infection in HIV-infected adults and evaluation of pooled NAT for HBV. J Viral Hepat 25:718-723
Steinhardt, James J; Guenaga, Javier; Turner, Hannah L et al. (2018) Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity. Nat Commun 9:877
Dinesha, Thongadi Ramesh; Boobalan, Jayaseelan; Sivamalar, Sathasivam et al. (2018) HIV, Hepatitis B Virus, and Hepatitis C Virus Prevalence Among High-Risk Populations in South India. AIDS Res Hum Retroviruses 34:327-328
Stecher, Melanie; Hoenigl, Martin; Eis-Hübinger, Anna Maria et al. (2018) Hotspots of Transmission Driving the Local Hiv Epidemic in the Cologne-Bonn Region, Germany. Clin Infect Dis :
Thaney, Victoria E; Sanchez, Ana B; Fields, Jerel A et al. (2018) Transgenic mice expressing HIV-1 envelope protein gp120 in the brain as an animal model in neuroAIDS research. J Neurovirol 24:156-167
Lin, Timothy C; Dijkstra, Maartje; De Bree, Godelieve J et al. (2018) Brief Report: The Amsterdam Symptom and Risk-Based Score Predicts for Acute HIV Infection in Men Who Have Sex With Men in San Diego. J Acquir Immune Defic Syndr 79:e52-e55
Hoenigl, Martin; Jain, Sonia; Moore, David et al. (2018) Substance Use and Adherence to HIV Preexposure Prophylaxis for Men Who Have Sex with Men1. Emerg Infect Dis 24:
Naticchia, Matthew R; Laubach, Logan K; Tota, Ember M et al. (2018) Embryonic Stem Cell Engineering with a Glycomimetic FGF2/BMP4 Co-Receptor Drives Mesodermal Differentiation in a Three-Dimensional Culture. ACS Chem Biol 13:2880-2887
Blumenthal, Jill; Jain, Sonia; Mulvihill, Evan et al. (2018) Perceived versus calculated HIV risk: Implications for Pre-exposure prophylaxis uptake in a randomized trial of men who have sex with men. J Acquir Immune Defic Syndr :

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