The UMass CFAR Clinical Core's mission is to provide the infrastructure and services that promoteinnovative patient-oriented and translational HIV research. The CFAR Clinical Core has the following goals:1) To facilitate interactions between basic scientists and clinical investigators that lead to patient-orientedstudies that improve our understanding of HIV pathogenesis and the development of novel prevention ortreatment strategies; 2) To provide the necessary expertise and services to facilitate patient-oriented andtranslational research; 3) To coordinate services with other CFAR Core Laboratories; 4) To support thetraining and advancement of new investigators in HIV-related research; and 5) To provide communityeducation regarding HIV and UMass CFAR Clinical HIV Research. The Clinical Core consists of a ClinicalSciences Core and a Clinical Immunology Core. The Clinical Sciences Core provides services that supportthe design, implementation, and analysis of patient-oriented and translational research with the goals ofstreamlining investigator training and protocol development. Other services provided by the ClinicalSciences Core include specimen receipt, processing, storage, and shipment; maintenance of extensive,integrated clinical (adult and pediatric) and laboratory databases; and a Bio-Statistics Sub-Core to providestatistical consultation for grant preparation, data analysis, and publications. The Clinical Immunology Coreprovides protocols, reagents, and services in support of patient-oriented and translational research. Inaddition, the UMass CFAR Clinical Core has recently partnered with the UMass Flow Cytometry Core todevelop a Biosafety Level 3 Flow Cytometry and Sorting Facility. Over the next funding period, the ClinicalCore will work with CFAR investigators and other CFAR Cores to provide services supporting studies thatimprove our understanding of HIV pathogenesis and strategies to prevent or treat HIV-1 infection.
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