The overall objective of the Virology Core is to provide comprehensive virologic services, reagents, and biosafety level 3 facilities to members of the Columbia Rockefeller Center for AIDS Research, thereby facilitating their research on HIV/SIV, broadening the scope of their investigation, and promoting meaningful collaborations. Major core services will include HIV/SIV isolation, propagation and titration; 2) viral quantification by culture, bDNA amplification, PCR and RT-PCR; 3) characterization of viral phenotype with respect to growth kinetics, syncytium-inducing capacity, cellular tropism, and co-receptor usage; 4) analysis of HIV/SIV genotype; 5) phenotype and genotypic characterization of drug resistance; and 6) determination of host cell susceptibility to HIV and co-receptor expression. The core will also provide valuable reagents and cell lines to CFAR members, as well as the use of biosafety level 3 space. These services and the overall virologic expertise in the Core should enhance the research activities of the CR-CFAR.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI042848-02
Application #
6201413
Study Section
Project Start
1999-09-01
Project End
2000-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Aaron Diamond AIDS Research Center
Department
Type
DUNS #
786658872
City
New York
State
NY
Country
United States
Zip Code
10016
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