Abstract

The major goal of the Penn-CFAR Developmental Core is the promotion of AIDS and HIV-related research at the University of Pennsylvania, the Children's Hospital of Philadelphia, and the Wistar Institute by providing a source of funding for pilot projects. The Developmental Core will support short term (1 year) projects in emerging areas of HIV research, including new research related to the recruitment of new investigators, research by established investigators who are turning their attention to AII3S, and research by AIDS/HIV investigators who are undertaking studies that represent a significant departure from their previous work. During the past funding period, we funded a total of 18 projects ranging in scope from molecular analysis of viruses and virus proteins, through the potential development of vaccine candidates, to sociological analysis of the transmission of sexual information in some African societies. A significant proportion of these pilot projects have been converted into fully funded NIH grants. We are proposing to fund 5 projects each year in years 6-10 of this CFAR, adding a new grant category devoted exclusively to interdisciplinary and/or translational research projects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI045008-06
Application #
6801288
Study Section
Special Emphasis Panel (ZAI1-AR-A (J3))
Project Start
2004-07-01
Project End
2009-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
6
Fiscal Year
2004
Total Cost
$251,421
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Vadrevu, Surya Kumari; Trbojevic-Akmacic, Irena; Kossenkov, Andrew V et al. (2018) Frontline Science: Plasma and immunoglobulin G galactosylation associate with HIV persistence during antiretroviral therapy. J Leukoc Biol 104:461-471
Loy, Dorothy E; Plenderleith, Lindsey J; Sundararaman, Sesh A et al. (2018) Evolutionary history of human Plasmodium vivax revealed by genome-wide analyses of related ape parasites. Proc Natl Acad Sci U S A 115:E8450-E8459
Dean, Lorraine T; Schmitz, Kathryn H; Frick, Kevin D et al. (2018) Consumer credit as a novel marker for economic burden and health after cancer in a diverse population of breast cancer survivors in the USA. J Cancer Surviv 12:306-315
Bui, Kevin D; Johnson, Michelle J (2018) Designing robot-assisted neurorehabilitation strategies for people with both HIV and stroke. J Neuroeng Rehabil 15:75
Hogan, Michael J; Conde-Motter, Angela; Jordan, Andrea P O et al. (2018) Increased surface expression of HIV-1 envelope is associated with improved antibody response in vaccinia prime/protein boost immunization. Virology 514:106-117
Salantes, D Brenda; Zheng, Yu; Mampe, Felicity et al. (2018) HIV-1 latent reservoir size and diversity are stable following brief treatment interruption. J Clin Invest 128:3102-3115
Lazar, Nellie Riendeau; Salas-Humara, Caroline; Wood, Sarah M et al. (2018) Missed Opportunities for HIV Screening Among a Cohort of Adolescents With Recently Diagnosed HIV Infection in a Large Pediatric Hospital Care Network. J Adolesc Health 63:799-802
Tawe, Leabaneng; Grover, Surbhi; Narasimhamurthy, Mohan et al. (2018) Molecular detection of human papillomavirus (HPV) in highly fragmented DNA from cervical cancer biopsies using double-nested PCR. MethodsX 5:569-578
Krump, Nathan A; Liu, Wei; You, Jianxin (2018) Mechanisms of persistence by small DNA tumor viruses. Curr Opin Virol 32:71-79
Gowda, Charitha; Lott, Stephen; Grigorian, Matthew et al. (2018) Absolute Insurer Denial of Direct-Acting Antiviral Therapy for Hepatitis C: A National Specialty Pharmacy Cohort Study. Open Forum Infect Dis 5:ofy076

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