Under the direction of Drs Jeffrey Lennox and Mark Mulligan, the primary goal of the Core D - Clinical Research Core (CRC) is to facilitate the design and implementation of clinical research studies that improve knowledge about, prevention of and treatment for, HIV infection in humans. Clinical and translational research encompasses studies involving human volunteers, clinical data, and/or human specimens. Core D serves Emory's NIH-funded HIV/AIDS researchers-and facilitates the entry of. new and/or junior researchers into the field. Clinical research studies may enroll HIV-infected or HIVuninfected volunteers in protocols focused on prevention or treatment of HIV infection. Translational research bridges basic science and clinical research, often providing the earliest insights into the human significance of preclinical laboratory and/or animal findings. The approach taken in Core D is that humans are the """"""""ultimate model"""""""". Hypotheses pertaining to studies or interventions designed to benefit mankind must be tested in rigorous scientific fashion. Core D activities will be supported through a mixture of CFAR support, Emory University support, charge-backs to Core D users when appropriate, and other leveraged support. Core D enhances the clinical and translational research activities of Emory CFAR investigators through the following Specific Aims:
Specific Aim 1. To encourage and enhance clinical and translational research studies conducted by Emory CFAR investigators.
Specific Aim 2. To provide clinical data and human specimens to Emory CFAR clinical and translational researchers.
Specific Aim 3. To support the mentoring and training of new, international, and minority faculty investigators and research staff in the field of HIV/AIDS clinical and translational research.
Specific Aim 4. To coordinate a program of communications to Emory CFAR investigators, as well as Atlanta area communities and community investigators, about the clinical and translational research opportunities available through Core D.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI050409-11
Application #
7922704
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2009-08-01
Budget End
2010-07-31
Support Year
11
Fiscal Year
2009
Total Cost
$337,341
Indirect Cost
Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Li, Binglan; Verma, Shefali S; Veturi, Yogasudha C et al. (2018) Evaluation of PrediXcan for prioritizing GWAS associations and predicting gene expression. Pac Symp Biocomput 23:448-459
Goodreau, Steven M; Hamilton, Deven T; Jenness, Samuel M et al. (2018) Targeting Human Immunodeficiency Virus Pre-Exposure Prophylaxis to Adolescent Sexual Minority Males in Higher Prevalence Areas of the United States: A Modeling Study. J Adolesc Health 62:311-319
Huang, Yijian; Wang, Ching-Yun (2018) Cox regression with dependent error in covariates. Biometrics 74:118-126
Winhusen, Theresa; Feaster, Daniel J; Duan, Rui et al. (2018) Baseline Cigarette Smoking Status as a Predictor of Virologic Suppression and CD4 Cell Count During One-Year Follow-Up in Substance Users with Uncontrolled HIV Infection. AIDS Behav 22:2026-2032
Sullivan, Patrick S; Purcell, David W; Grey, Jeremy A et al. (2018) Patterns of Racial/Ethnic Disparities and Prevalence in HIV and Syphilis Diagnoses Among Men Who Have Sex With Men, 2016: A Novel Data Visualization. Am J Public Health 108:S266-S273
Wells, Jessica S; Holstad, Marcia M; Watkins Bruner, Deborah (2018) Sociodemographic Predictors of Anal Cancer Screening and Follow-up in Human Immunodeficiency Virus-Infected Individuals. Cancer Nurs 41:424-430
Luo, Wei; Katz, David A; Hamilton, Deven T et al. (2018) Development of an Agent-Based Model to Investigate the Impact of HIV Self-Testing Programs on Men Who Have Sex With Men in Atlanta and Seattle. JMIR Public Health Surveill 4:e58
Eaton, Lisa A; Kalichman, Seth C; Kalichman, Moira O et al. (2018) Randomised controlled trial of a sexual risk reduction intervention for STI prevention among men who have sex with men in the USA. Sex Transm Infect 94:40-45
Wall, Kristin M; Inambao, Mubiana; Kilembe, William et al. (2018) HIV testing and counselling couples together for affordable HIV prevention in Africa. Int J Epidemiol :
Martin, Maureen P; Naranbhai, Vivek; Shea, Patrick R et al. (2018) Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. J Clin Invest 128:1903-1912

Showing the most recent 10 out of 1005 publications