The challenges posed by the HIV/AIDS epidemic are tackled most effectively by creatively integrating biomedical, social and behavioral approaches. Although dramatic advances have been made in our understanding of vaccine development'and the effective treatment of HIV, poor medication adherence, stigma associated with HIV, and disparities in health services delivery limit the impact of biomedical advances. Significant progress has also been made in understanding viral pathogenesis and transmission. Translating this progress into reduced incidence of HIV, however, requires knowledge of efficacious methods to change human behavior. Optimal strategies are needed to disseminate and integrate into routine care behavioral approaches that are found to be effective. Interventions that target multiple levels, biologic and behavioral, are most likely to be effective but require collaboration across disciplines. The overarching goal of the UNC CFAR's Social and Behavioral Core is to facilitate collaborative HIV/AIDS research efforts that integrate biomedical and social science approaches. In this renewal application, we focus on three specific aims: 1) to support ongoing HIV/AIDS social and behavioral research as well as social and behavioral components of ongoing HIV/AIDS biomedical research by providing technical assistance in a number of areas;2) to support and enhance the communication and collaboration of existing HIV/AIDS Social and Behavioral researchers with each other and with biomedical researchers;and 3) to plan new research initiatives that address novel, high priority social and behavioral aspects of the HIV/AIDS epidemic. We will achieve these goals by creating and maintaining an archive of evidence-based prevention interventions and measurement tools that assess psychosocial aspects of HIV/AIDS. We will also continue to help sponsor eekly CFAR seminars as well as develop and put on an annual Social and Behavioral HIV/AIDS Research symposium. These forums provide an opportunity to exchange ideas and develop novel collaborative endeavors. We will create an updated Social and Behavioral Researchers Resource Directory and, once updated, put it onlline to enhance its usability. We will work closely with other cores to enhance the use and dissemination of social and behavioral analyses of data in the UNC clinical database. Core G users represent a broad range of productive social and biomedical scholars from across several UNC Schools, FHI and RTI.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of North Carolina Chapel Hill
Chapel Hill
United States
Zip Code
Lancaster, Kathryn E; MacLean, Sarah A; Lungu, Thandie et al. (2018) Socioecological Factors Related to Hazardous Alcohol use among Female Sex Workers in Lilongwe, Malawi: A Mixed Methods Study. Subst Use Misuse 53:782-791
Sharma, Anjali; Hoover, Donald R; Shi, Qiuhu et al. (2018) Longitudinal study of falls among HIV-infected and uninfected women: the role of cognition. Antivir Ther 23:179-190
Ke, Ruian; Conway, Jessica M; Margolis, David M et al. (2018) Determinants of the efficacy of HIV latency-reversing agents and implications for drug and treatment design. JCI Insight 3:
Conserve, Donaldson F; Alemu, Dawit; Yamanis, Thespina et al. (2018) ""He Told Me to Check My Health"": A Qualitative Exploration of Social Network Influence on Men's HIV Testing Behavior and HIV Self-Testing Willingness in Tanzania. Am J Mens Health 12:1185-1196
Zhang, Helen L; Rhea, Sarah K; Hurt, Christopher B et al. (2018) HIV Preexposure Prophylaxis Implementation at Local Health Departments: A Statewide Assessment of Activities and Barriers. J Acquir Immune Defic Syndr 77:72-77
Haley, Danielle F; Edmonds, Andrew; Belenky, Nadya et al. (2018) Neighborhood Health Care Access and Sexually Transmitted Infections Among Women in the Southern United States: A Cross-Sectional Multilevel Analysis. Sex Transm Dis 45:19-24
Galárraga, Omar; Rana, Aadia; Rahman, Momotazur et al. (2018) The effect of unstable housing on HIV treatment biomarkers: An instrumental variables approach. Soc Sci Med 214:70-82
Potempa, Marc; Lee, Sook-Kyung; Kurt Yilmaz, Nese et al. (2018) HIV-1 Protease Uses Bi-Specific S2/S2' Subsites to Optimize Cleavage of Two Classes of Target Sites. J Mol Biol 430:5182-5195
Dubé, Karine; Evans, David; Dee, Lynda et al. (2018) ""We Need to Deploy Them Very Thoughtfully and Carefully"": Perceptions of Analytical Treatment Interruptions in HIV Cure Research in the United States-A Qualitative Inquiry. AIDS Res Hum Retroviruses 34:67-79
Hampel, Daniela; Shahab-Ferdows, Setareh; Gertz, Erik et al. (2018) The effects of a lipid-based nutrient supplement and antiretroviral therapy in a randomized controlled trial on iron, copper, and zinc in milk from HIV-infected Malawian mothers and associations with maternal and infant biomarkers. Matern Child Nutr 14:e12503

Showing the most recent 10 out of 1688 publications