The Tennessee Center for AIDS Research (CFAR) is a four-way partnership between a research-intensive institution (Vanderbilt University Medical Center), a historically black medical college (Meharry Medical College), an academically-engaged state health department (Tennessee Department of Health), and a sophisticated community-based organization with a 25-year exclusive focus on HIV (Nashville CARES). The Developmental Core (DC) will support and enhance collaborative, interdisciplinary HIV/AIDS research at the four partner institutions. Invigorated by new DC initiatives and leadership, the DC will pursue three complementary objectives: 1) To administer a robust CFAR DC Awards program that supports interdisciplinary HIV research projects and new HIV research pilot projects; 2) To ensure mentoring of investigators new to HIV research, with a focus on early stage, minority, women, and public health investigators, to enhance competitiveness for extramural funding, and; 3) To foster academic skills development and scientific team-building. In 2019, the DC leadership structure transitioned, with John Koethe, MD, MSCI, Associate Professor of Medicine at Vanderbilt, assuming the role of DC Director, supported by Fernando Villalta, PhD and Tim Sterling, MD as Associate Directors. This change was in response to extensive strategic planning, with input from the our CFAR External and Internal Scientific Advisory Boards, as part of succession planning for the upcoming funding cycle of this CFAR. The DC will not only provide DC Award funding for promising early-stage investigators but will continue to assure that there is appropriate mentoring together with activities to foster team building. This will help early-stage investigators appreciate the critical importance of effective collaboration as they develop into accomplished academic research scientists. The HIV-focused DC Awards, mentoring, and skills development will be leveraged with outstanding institutional support at Vanderbilt (through the Vanderbilt Institute for Clinical and Translational Research; VICTR) and at Meharry (through the Meharry Translational Research Center; MeTRC, and the Center for Health Disparities Research at MMC) to maximize the potential for important, ground-breaking research that will lead to extramural funding support, and that ultimately has substantial impact on the burden of HIV in Tennessee, the nation, and worldwide.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI110527-06
Application #
9996153
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2020-04-21
Budget End
2021-03-31
Support Year
6
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
DUNS #
079917897
City
Nashville
State
TN
Country
United States
Zip Code
37232
Rebeiro, Peter F; Howe, Chanelle J; Rogers, William B et al. (2018) The relationship between adverse neighborhood socioeconomic context and HIV continuum of care outcomes in a diverse HIV clinic cohort in the Southern United States. AIDS Care 30:1426-1434
Altekruse, Sean F; Shiels, Meredith S; Modur, Sharada P et al. (2018) Cancer burden attributable to cigarette smoking among HIV-infected people in North America. AIDS 32:513-521
Balasubramaniam, Muthukumar; Zhou, Jing; Addai, Amma et al. (2018) PF74 Inhibits HIV-1 Integration by Altering The Composition of the Preintegration Complex. J Virol :
Tan, Yi; Tsan-Yuk Lam, Tommy; Heberlein-Larson, Lea A et al. (2018) Large scale complete genome sequencing and phylodynamic analysis of eastern equine encephalitis virus reveal source-sink transmission dynamics in the United States. J Virol :
Rickles, Michael; Rebeiro, Peter F; Sizemore, Lindsey et al. (2018) Tennessee's In-state Vulnerability Assessment for a ""Rapid Dissemination of Human Immunodeficiency Virus or Hepatitis C Virus Infection"" Event Utilizing Data About the Opioid Epidemic. Clin Infect Dis 66:1722-1732
Koethe, John R; McDonnell, Wyatt; Kennedy, Arion et al. (2018) Adipose Tissue is Enriched for Activated and Late-Differentiated CD8+ T Cells and Shows Distinct CD8+ Receptor Usage, Compared With Blood in HIV-Infected Persons. J Acquir Immune Defic Syndr 77:e14-e21
Stone Jr, Cosby A; Liu, Yiwei; Relling, Mary V et al. (2018) Immediate Hypersensitivity to Polyethylene Glycols and Polysorbates: More Common Than We Have Recognized. J Allergy Clin Immunol Pract :
Li, Binglan; Verma, Shefali S; Veturi, Yogasudha C et al. (2018) Evaluation of PrediXcan for prioritizing GWAS associations and predicting gene expression. Pac Symp Biocomput 23:448-459
Leger, Paul; Chirwa, Sanika; Nwogu, Jacinta N et al. (2018) Race/ethnicity difference in the pharmacogenetics of bilirubin-related atazanavir discontinuation. Pharmacogenet Genomics 28:1-6
Trubiano, Jason A; Strautins, Kaija; Redwood, Alec J et al. (2018) The Combined Utility of Ex Vivo IFN-? Release Enzyme-Linked ImmunoSpot Assay and In Vivo Skin Testing in Patients with Antibiotic-Associated Severe Cutaneous Adverse Reactions. J Allergy Clin Immunol Pract 6:1287-1296.e1

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