Abstract

ENDING THE HIV EPIDEMIC SCIENTIFIC WORKING GROUP (SWG 2) PROJECT SUMMARY The Ending the HIV Epidemic (EHE) Scientific Working Group (SWG) will catalyze and coordinate the development of high-impact implementation science initiatives by DC CFAR investigators. Developed strategically to respond to the national EHE initiative, the SWG will leverage the citywide ?DC model? and engage investigators from multiple academic institutions to develop innovative strategies that will contribute to bringing an end to the epidemic in Washington, DC and beyond in partnership with local government and community.
The Specific Aims of the EHE SWG are: 1) to catalyze the development of high-impact implementation science initiatives that will contribute to bringing an end to the HIV epidemic in local, regional and national ?hotspots?; 2) to support innovative science for the four pillars of the national EHE initiative - diagnose, treat, prevent and respond; and 3) to engage early stage, women and underrepresented minority investigators in implementation science and the EHE initiative.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI117970-06
Application #
9986265
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2020-06-01
Budget End
2021-05-31
Support Year
6
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
George Washington University
Department
Type
DUNS #
043990498
City
Washington
State
DC
Country
United States
Zip Code
20052

  Publications

Desrosiers, Aimee; Levy, Matthew; Dright, Aurnell et al. (2018) A Randomized Controlled Pilot Study of a Culturally-Tailored Counseling Intervention to Increase Uptake of HIV Pre-exposure Prophylaxis Among Young Black Men Who Have Sex with Men in Washington, DC. AIDS Behav :
Ghosh, Mimi; Daniels, Jason; Pyra, Maria et al. (2018) Impact of chronic sexual abuse and depression on inflammation and wound healing in the female reproductive tract of HIV-uninfected and HIV-infected women. PLoS One 13:e0198412
Houzet, Laurent; Pérez-Losada, Marcos; Matusali, Giulia et al. (2018) Seminal Simian Immunodeficiency Virus in Chronically Infected Cynomolgus Macaques Is Dominated by Virus Originating from Multiple Genital Organs. J Virol 92:
Macedo, Amanda B; Novis, Camille L; De Assis, Caroline M et al. (2018) Dual TLR2 and TLR7 agonists as HIV latency-reversing agents. JCI Insight 3:
Ren, Yanqin; Korom, Maria; Truong, Ronald et al. (2018) Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs. J Virol 92:
Orekhov, Alexander N; Pushkarsky, Tatiana; Oishi, Yumiko et al. (2018) HDL activates expression of genes stimulating cholesterol efflux in human monocyte-derived macrophages. Exp Mol Pathol 105:202-207
Huang, Szu-Han; Ren, Yanqin; Thomas, Allison S et al. (2018) Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells. J Clin Invest 128:876-889
Adzhubei, Alexei A; Anashkina, Anastasia A; Tkachev, Yaroslav V et al. (2018) Modelling interaction between HIV-1 Nef and calnexin. AIDS 32:2103-2111
Clutton, Genevieve Tyndale; Jones, R Brad (2018) Diverse Impacts of HIV Latency-Reversing Agents on CD8+ T-Cell Function: Implications for HIV Cure. Front Immunol 9:1452
Ghosh, Mimi; Jais, Mariel; Biswas, Roshni et al. (2018) Immune biomarkers and anti-HIV activity in the reproductive tract of sexually active and sexually inactive adolescent girls. Am J Reprod Immunol 79:e12846

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