The Molecular Biology Core provides 1) expertise and advice in the area of molecular biological techniques, 2) a central facility for the collection and storage of cDNA and genomic DNA clones, 3) a training center where SDRC investigators can learn molecular techniques relevant to the study of skin, 4) resources and equipment for the synthesis and purification of synthetic oligonucleotides, and 5) a centralized, fully equipped facility for hands-on training of SDRC investigators and associates. This core was very successfully utilized during the past five years, and its continued function is essential for maintenance and expansion of the SDRC's research base.

Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Das, Lopa M; Binko, Amy M; Traylor, Zachary P et al. (2018) Defining the timing of 25(OH)D rescue following nitrogen mustard exposure. Cutan Ocul Toxicol 37:127-132
Griffith, Alexis D; Zaidi, Asifa K; Pietro, Ashley et al. (2018) A requirement for slc15a4 in imiquimod-induced systemic inflammation and psoriasiform inflammation in mice. Sci Rep 8:14451
Zaidi, Asifa K; Spaunhurst, Katrina; Sprockett, Daniel et al. (2018) Characterization of the facial microbiome in twins discordant for rosacea. Exp Dermatol 27:295-298
Bhaskaran, Natarajan; Liu, Zhihui; Saravanamuthu, Senthil S et al. (2018) Identification of Casz1 as a Regulatory Protein Controlling T Helper Cell Differentiation, Inflammation, and Immunity. Front Immunol 9:184
Mukherjee, Pranab K; Chandra, Jyotsna; Retuerto, Mauricio et al. (2018) Effect of alcohol-based hand rub on hand microbiome and hand skin health in hospitalized adult stem cell transplant patients: A pilot study. J Am Acad Dermatol 78:1218-1221.e5
Soler, David C; Young, Andrew E; Griffith, Alexis D et al. (2017) Overexpression of AQP3 and AQP10 in the skin exacerbates psoriasiform acanthosis. Exp Dermatol 26:949-951
Wang, QuanQiu; McCormick, Thomas S; Ward, Nicole L et al. (2017) Combining mechanism-based prediction with patient-based profiling for psoriasis metabolomics biomarker discovery. AMIA Annu Symp Proc 2017:1734-1743
Fritz, Yi; Klenotic, Philip A; Swindell, William R et al. (2017) Induction of Alternative Proinflammatory Cytokines Accounts for Sustained Psoriasiform Skin Inflammation in IL-17C+IL-6KO Mice. J Invest Dermatol 137:696-705
Scott, Jeffrey F; Das, Lopa M; Ahsanuddin, Sayeeda et al. (2017) Oral Vitamin D Rapidly Attenuates Inflammation from Sunburn: An Interventional Study. J Invest Dermatol 137:2078-2086
Monin, Leticia; Gudjonsson, Johann E; Childs, Erin E et al. (2017) MCPIP1/Regnase-1 Restricts IL-17A- and IL-17C-Dependent Skin Inflammation. J Immunol 198:767-775

Showing the most recent 10 out of 403 publications