The major goal of the Analytical Microscopy Laboratory is to provide technical expertise in qualitative andquantitative analytical microscopy and to extend these capabilities to all relevant studies in orthopaedics andmusculoskeletal research.The Analytical Microscopy Core has four major objectives:1. To provide morphological techniques and analysis for the study of soft and hard tissues at the light andelectron microscopic levels for research programs involving investigators within the biomedical researchbase at the Hospital for Special Surgery (HSS) and its affiliated institutions;2. To provide information and training to all investigators regarding the use of techniques in histology,histochemistry, immunocytochemistry and morphometry;3. To develop further our capacity for systematic and quantitative evaluation of fixed arid living cellsanalyzed by microscopic techniques (including confocal microscopy); and,4. To develop new applications of microscopic techniques to fit the research programs of investigatorswithin the Core Center's biomedical research base.This laboratory is unique because the techniques, technical support, and equipment is specifically designedto aid in the study of all musculoskeletal tissues, whether mineralized or not. In addition, the studies can bedone at any level of interest from the gross to the subcellular, and because of the working relationships withthe other cores, each study can be investigated for change in morphology, chemistry, and mechanics orarchitec-ture. This environment is very unique and probably does not exist anywhere else in the UnitedStates. Because of these strengths, the projects and studies being supported will add significantly to ourknowledge of musculoskeletal tissue development and repair.
Showing the most recent 10 out of 195 publications
