Abstract

The Administrative Core will manage, coordinate and evaluate all aspects of the University of Colorado Skin Diseases Research Core Center (UCAMC-SDRC), We will add Xiao-Jing Wang to our leadership team of David Norris, Dennis Roop and Richard Spritz, but will retain most features of the successful Administrative Structure from the first 4 years of funding.

Public Health Relevance

This proposal will address research areas highly relevant to NIAMS priorities: biology of skin stem cells; regenerative medicine; developmental biology of the skin and appendages; melanocyte biology; keratinocyte differentiation; immune and inflammatory skin diseases; adaptive and innate immunity; identification of the genetic basis of skin disease and development of animal models to study those diseases.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Center Core Grants (P30)
Project #
2P30AR057212-06
Application #
8753455
Study Section
Special Emphasis Panel (ZAR1-KM (M1))
Project Start
Project End
Budget Start
2014-08-20
Budget End
2015-07-31
Support Year
6
Fiscal Year
2014
Total Cost
$215,418
Indirect Cost
$76,476

  Institution

Name
University of Colorado Denver
Department
Type
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

Cao, Yu; Liu, Han; Gao, Liwei et al. (2018) Cooperation Between Pten and Smad4 in Murine Salivary Gland Tumor Formation and Progression. Neoplasia 20:764-774
Mukherjee, Nabanita; Strosnider, Andrew; Vagher, Bay et al. (2018) BH3 mimetics induce apoptosis independent of DRP-1 in melanoma. Cell Death Dis 9:907
Kogut, Igor; McCarthy, Sandra M; Pavlova, Maryna et al. (2018) High-efficiency RNA-based reprogramming of human primary fibroblasts. Nat Commun 9:745
Riching, Andrew S; Zhao, Yuanbiao; Cao, Yingqiong et al. (2018) Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes. J Vis Exp :
Ravindran Menon, Dinoop; Luo, Yuchun; Arcaroli, John J et al. (2018) CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma. Cancer Res 78:6561-6574
Gaskill, Christa F; Carrier, Erica J; Kropski, Jonathan A et al. (2017) Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction. J Clin Invest 127:2262-2276
Mukherjee, Nabanita; Lu, Yan; Almeida, Adam et al. (2017) Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells. Oncotarget 8:46801-46817
Miller, Shannon M; Miles, Brodie; Guo, Kejun et al. (2017) Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1. J Virol 91:
Yang, N; Leung, E L-H; Liu, C et al. (2017) INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma. Oncogene 36:4997-5005
Shah, Khadim; Mehmood, Sabba; Jan, Abid et al. (2017) Sequence variants in nine different genes underlying rare skin disorders in 10 consanguineous families. Int J Dermatol 56:1406-1413

Showing the most recent 10 out of 61 publications