Administrative Core The Administrative Core will manage and oversee all activities of the Center and carry out Outreach Activities, which are of paramount importance to the Center. This is a Center that both pulls in, bringing visiting scholars to Harvard for training in human-based techniques and bringing new investigators into human skin disease research, and a center that pushes out, exporting knowledge and the ability to use new and powerful techniques to members of the scientific community. The Administrative Core will make the Center activities accessible to the Research Community, organize ongoing complex, multi-institutional activities, and provide the leadership necessary to establish a dynamic and flexible Center that can rapidly respond to the changing landscape of science, remaining state-of-the-art and responsive to users' needs. The Administrative Core will establish and support the Executive Committee and the internal and external members of the Advisory Committee, composed of experts in human translational research who have leadership experience with complex multi-center grants. The Administrative Core will manage and support the Resource Cores by maintaining frequent contact with each component Core, including bimonthly communications of Center and Core leaders, quarterly communications of all Core and Center leaders and biannual conference calls with Center leaders, Core leaders, and the Advisory Committee. The Administrative Core will build and maintain a centralized Internet site, the HSDRC Portal, which will serve as a central meeting place for Center leadership and the research community. The Internal Portal, accessible only to Center leaders and staff, will track all core users, the dates of core usage, usage charges, waiting lists and feedback quality scores. The External Center Portal, which is accessible to the public, will provide access to information on Center services, links to Core contacts, access to Outreach activities and summaries of research carried out by Center investigators. Outreach activities of the Administrative Core will include two grant mechanisms, Translation Accelerator Grants, meant to fund pilot human-based studies, and Visiting Scholar grants, which will support a three to six month period of study at the Center for investigators who wish to gain hands-on training and experience in human-based research. Other Outreach activities include quarterly podcasts, webcasts, and instructional videos that will be posted on the Center Portal and the Human Skin Disease Research Center YouTube channel. Lastly, the Administrative Core will support a biennial International Conference on Human Skin Diseases which will present cutting-edge human skin disease research by internationally recognized investigators and will also serve to publicize Center services and the results of Center Investigators. In summary, the Administrative Core provides vision and leadership to the Center, coordinates and centralizes the activities of the Resource Cores, and administers Outreach activities that publicize the Center activities, support skin disease researchers and bring new researchers into the field of human skin disease research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Center Core Grants (P30)
Project #
5P30AR069625-05
Application #
9969340
Study Section
Special Emphasis Panel (ZAR1)
Project Start
Project End
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
5
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Cotton, Rachel N; Shahine, Adam; Rossjohn, Jamie et al. (2018) Lipids hide or step aside for CD1-autoreactive T cell receptors. Curr Opin Immunol 52:93-99
Gehad, Ahmed; Teague, Jessica E; Matos, Tiago R et al. (2018) A primary role for human central memory cells in tissue immunosurveillance. Blood Adv 2:292-298
Park, Chang Ook; Fu, Xiujun; Jiang, Xiaodong et al. (2018) Staged development of long-lived T-cell receptor ?? TH17 resident memory T-cell population to Candida albicans after skin infection. J Allergy Clin Immunol 142:647-662
Malhotra, Nidhi; Leyva-Castillo, Juan Manuel; Jadhav, Unmesh et al. (2018) ROR?-expressing T regulatory cells restrain allergic skin inflammation. Sci Immunol 3:
Sparks, Jeffrey A; Lin, Tzu-Chieh; Camargo Jr, Carlos A et al. (2018) Rheumatoid arthritis and risk of chronic obstructive pulmonary disease or asthma among women: A marginal structural model analysis in the Nurses' Health Study. Semin Arthritis Rheum 47:639-648
Prado, Maria G; Iversen, Maura D; Yu, Zhi et al. (2018) Effectiveness of a Web-Based Personalized Rheumatoid Arthritis Risk Tool With or Without a Health Educator for Knowledge of Rheumatoid Arthritis Risk Factors. Arthritis Care Res (Hoboken) 70:1421-1430
de Masson, Adele; O'Malley, John T; Elco, Christopher P et al. (2018) High-throughput sequencing of the T cell receptor ? gene identifies aggressive early-stage mycosis fungoides. Sci Transl Med 10:
Sparks, Jeffrey A; Iversen, Maura D; Yu, Zhi et al. (2018) Disclosure of Personalized Rheumatoid Arthritis Risk Using Genetics, Biomarkers, and Lifestyle Factors to Motivate Health Behavior Improvements: A Randomized Controlled Trial. Arthritis Care Res (Hoboken) 70:823-833
Win, Thet Su; Murakami, Naoka; Borges, Thiago J et al. (2017) Longitudinal immunological characterization of the first presensitized recipient of a face transplant. JCI Insight 2:
Moody, D Branch; Cotton, Rachel N (2017) Four pathways of CD1 antigen presentation to T cells. Curr Opin Immunol 46:127-133

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