The primary objectives of the Administrative Core of the Johns Hopkins Rheumatic Diseases Resource-based Core Center (RDRCC) are to integrate all scientific and enrichment activities of the Cores, maintain communication between the Cores and with the research base, and provide budgetary management and oversight, all within the context of the overall Divisional and institutional clinical/ translational research framework. The RDRCC and its Administrative Core is led by Drs. Antony Rosen and Clifton Bingham (as Co-Directors). Their complementary research approaches from the opposite ends of the research spectrum (laboratory and clinical respectively) underscore the Center's ability to enable research along the entire translational research continuum.
The Specific Aims of the Administrative Core of the RDRCC are to:1) Oversee, coordinate, and actively manage the logistic and financial aspects of three Scientific Cores (Core B--Research Management and Patient Integrated Data [RAPID], Core C--Sample Processing and Immunoassay Research, SPIRE; and Core D--Data Science); 2) Continually work to decrease barriers to effective, cross-disciplinary interaction amongst investigators focused on the rheumatic diseases; 3) Use innovative approaches to interface with the Divisional Discovery Fund program and institutional resources to maximize RDRCC Core utilization by novel projects focused on the rheumatic diseases; 4) Foster the careers of junior investigators; 5) Initiate and support innovative collaborations between Center investigators and investigators new to rheumatic diseases with complementary expertise and interests; 6) Coordinate a program of enrichment activities to enhance research methodological literacy and the overall intellectual environment across disciplines. Each of these components will work together through the Administrative Core to enable research in the Rheumatic Diseases to thrive and expand.

National Institute of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Center Core Grants (P30)
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Special Emphasis Panel (ZAR1)
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Johns Hopkins University
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Wohlfahrt, Alyssa; Bingham 3rd, Clifton O; Marder, Wendy et al. (2018) Responsiveness of Patient Reported Outcomes Measurement Information System (PROMIS) Measures in RA Patients Starting or Switching a DMARD. Arthritis Care Res (Hoboken) :
Darrah, Erika; Giles, Jon T; Davis, Ryan L et al. (2018) Autoantibodies to Peptidylarginine Deiminase 2 Are Associated With Less Severe Disease in Rheumatoid Arthritis. Front Immunol 9:2696
Leung, Ying Ying; Ogdie, Alexis; Orbai, Ana-Maria et al. (2018) Classification and Outcome Measures for Psoriatic Arthritis. Front Med (Lausanne) 5:246
Bartlett, S J; Gutierrez, A K; Butanis, A et al. (2018) Combining online and in-person methods to evaluate the content validity of PROMIS fatigue short forms in rheumatoid arthritis. Qual Life Res 27:2443-2451
Darrah, Erika; Yu, Fang; Cappelli, Laura C et al. (2018) Association of baseline peptidylarginine deiminase 4 autoantibodies with favorable response to treatment escalation in rheumatoid arthritis. Arthritis Rheumatol :
Albayda, Jemima; Bingham 3rd, Clifton O; Shah, Ami A et al. (2018) Metastatic joint involvement or inflammatory arthritis? A conundrum with immune checkpoint inhibitor-related adverse events. Rheumatology (Oxford) 57:760-762
Cappelli, Laura C; Konig, Maximilian F; Gelber, Allan C et al. (2018) Smoking is not linked to the development of anti-peptidylarginine deiminase 4 autoantibodies in rheumatoid arthritis. Arthritis Res Ther 20:59
Igusa, Takeru; Hummers, Laura K; Visvanathan, Kala et al. (2018) Autoantibodies and scleroderma phenotype define subgroups at high-risk and low-risk for cancer. Ann Rheum Dis 77:1179-1186
Cappelli, Laura C; Brahmer, Julie R; Forde, Patrick M et al. (2018) Clinical presentation of immune checkpoint inhibitor-induced inflammatory arthritis differs by immunotherapy regimen. Semin Arthritis Rheum 48:553-557
Lee, Yvonne C; Bingham 3rd, Clifton O; Edwards, Robert R et al. (2018) Association Between Pain Sensitization and Disease Activity in Patients With Rheumatoid Arthritis: A Cross-Sectional Study. Arthritis Care Res (Hoboken) 70:197-204

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