Addressing racial disparities in rheumatic diseases as complex as systemic lupus erythematosus and systemic sclerosis requires interdisciplinary approaches that involve strong methodological components. The overarching objectives of the CCCR Methodologic Core are to enhance the quality of research conducted by investigators in the CCCR Research Base and to provide leadership on investigations relevant to minority health in rheumatic diseases. To achieve these objectives within the CCCR, the Methodologic Core has 4 aims: 1) provide quantitative guidance to the CCCR Research Base; 2) conduct research to develop novel biostatistics methods; 3) participate in educational development of clinical and translational investigators; and 4) serve as liaisons between the CCCR Research Base and other quantitative experts. The Core is comprised of 4 PhD faculty with expertise in biostatistics, bioinformatics, and epidemiology, all of whom have a strong track record of collaboration with rheumatologists, clinically-relevant methods development, and education. Through interactions with our CTSA program and other important resources, the Core will also be able to leverage additional expertise as needed. By achieving these aims through innovative techniques, the Methodologic Core will help continue to ensure that MUSC is a leading entity in rheumatologic research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Center Core Grants (P30)
Project #
1P30AR072582-01
Application #
9413807
Study Section
Special Emphasis Panel (ZAR1)
Project Start
Project End
Budget Start
2017-09-18
Budget End
2018-08-31
Support Year
1
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Medical University of South Carolina
Department
Type
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29403
Pandey, Janardan P; Namboodiri, Aryan M; Wolf, Bethany et al. (2018) Endogenous antibody responses to mucin 1 in a large multiethnic cohort of patients with breast cancer and healthy controls: Role of immunoglobulin and Fc? receptor genes. Immunobiology 223:178-182
Nguyen, Xinh-Xinh; Muhammad, Lutfiyya; Nietert, Paul J et al. (2018) IGFBP-5 Promotes Fibrosis via Increasing Its Own Expression and That of Other Pro-fibrotic Mediators. Front Endocrinol (Lausanne) 9:601
Faith, Trevor D; Egede, Leonard; Williams, Edith M (2018) Research Ethics in Behavioral Interventions Among Special Populations: Lessons From the Peer Approaches to Lupus Self-Management Study. Am J Med Sci 355:104-112
Putterman, Chaim; Pisetsky, David S; Petri, Michelle et al. (2018) The SLE-key test serological signature: new insights into the course of lupus. Rheumatology (Oxford) 57:1632-1640
Ruiz, Daniel; Oates, Jim C; Kamen, Diane L (2018) Antiphospholipid Antibodies and Heart Valve Disease in Systemic Lupus Erythematosus. Am J Med Sci 355:293-298
Fair, Patricia A; White, Natasha D; Wolf, Beth et al. (2018) Persistent organic pollutants in fish from Charleston Harbor and tributaries, South Carolina, United States: A risk assessment. Environ Res 167:598-613
Williams, Edith M; Hyer, J Madison; Viswanathan, Ramakrishnan et al. (2018) Peer-to-Peer Mentoring for African American Women With Lupus: A Feasibility Pilot. Arthritis Care Res (Hoboken) 70:908-917
Flournoy-Floyd, Minnjuan; Ortiz, Kasim; Egede, Leonard et al. (2018) ""We Would Still Find Things to Talk About"": Assessment of Mentor Perspectives in a Systemic Lupus Erythematosus Intervention to Improve Disease Self-Management, Empowering SLE Patients. J Natl Med Assoc 110:182-189
Williams, Edith M; Egede, Leonard; Faith, Trevor et al. (2017) Effective Self-Management Interventions for Patients With Lupus: Potential Impact of Peer Mentoring. Am J Med Sci 353:580-592
Williams, Edith M; Hyer, J Madison; Viswanathan, Ramakrishnan et al. (2017) Cytokine balance and behavioral intervention; findings from the Peer Approaches to Lupus Self-Management (PALS) project. Hum Immunol 78:574-581

Showing the most recent 10 out of 13 publications