The Johns Hopkins Comprehensive Cancer Center is dedicated to research in education and cancer and related disorders and to the prompt application of new knowledge to the treatment of patients and to the prevention of neoplastic diseases. The Johns Hopkins Comprehensive Cancer Center is a multi-disciplinary, interdepartmental center of the Johns Hopkins University. There is a broad base of ongoing cancer research at Johns Hopkins. The specific scientific programs of the Cancer Center are interdisciplinary in character and are focused on human disease. A wide range of activity of encompassed ranging from fundamental research into the molecular genetics of human tumorigenesis to clinical trials of new anti-tumor treatments. The Cancer Center research into the molecular genetics of human tumorigenesis to clinical trials of new anti-tumor treatments. The Cancer Center has established seven major research programs: Cancer Biology, Experimental and Therapeutic Hematopoiesis, Experimental Therapeutics/Solid Tumor Research, Cancer Immunology, Viral Oncology, Cancer Prevention and Control, and Urologic Oncology. Fifteen Shared Resources support the needs of Cancer Center investigators: Cell Sorting and Imaging Core, Animal Resources, Vector Core, Experimental Irradiators, Glassware Washing, Common Equipment, Molecular Pathology Core/Hematologic Malignancy Cell Procurement, Cytogenetics and Molecular Genetics, Pharmacology Analytic, Hematopoietic and Therapeutic Support, Cell and Gene Therapy, Research Pharmacy, Biostatistics, and Clinical Research Office. Interdisciplinary research seminars and research training programs provide valuable opportunities for interdisciplinary interaction and collaboration. Cancer Center developmental founds are used to support faculty recruitment and innovative research; development of shared resources; and a small allocation to pilot projects.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA006973-43
Application #
6891663
Study Section
Subcommittee G - Education (NCI)
Program Officer
Silkensen, Shannon M
Project Start
1978-01-01
Project End
2006-04-30
Budget Start
2005-05-01
Budget End
2006-04-30
Support Year
43
Fiscal Year
2005
Total Cost
$6,223,765
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Woodard, Lauren E; Dennis, Cindi L; Borchers, Julie A et al. (2018) Nanoparticle architecture preserves magnetic properties during coating to enable robust multi-modal functionality. Sci Rep 8:12706
Shrestha, Eva; White, James R; Yu, Shu-Han et al. (2018) Profiling the Urinary Microbiome in Men with Positive versus Negative Biopsies for Prostate Cancer. J Urol 199:161-171
Gordy, James T; Luo, Kun; Francica, Brian et al. (2018) Anti-IL-10-mediated Enhancement of Antitumor Efficacy of a Dendritic Cell-targeting MIP3?-gp100 Vaccine in the B16F10 Mouse Melanoma Model Is Dependent on Type I Interferons. J Immunother 41:181-189
El-Diwany, Ramy; Soliman, Mary; Sugawara, Sho et al. (2018) CMPK2 and BCL-G are associated with type 1 interferon-induced HIV restriction in humans. Sci Adv 4:eaat0843
Kyker-Snowman, Kelly; Erlanger Avigdor, Bracha; Nasim, Mansoor et al. (2018) A primary breast cancer with distinct foci of estrogen receptor-alpha positive and negative cells derived from the same clonal origin as revealed by whole exome sequencing. Breast Cancer Res Treat 170:425-430
Christenson, Eric S; Antonarakis, Emmanuel S (2018) PARP inhibitors for homologous recombination-deficient prostate cancer. Expert Opin Emerg Drugs 23:123-133
Ambinder, Richard F (2018) A viral protein kinase drug target for tumors? J Clin Invest 128:2197-2198
Lee, Alice J; Montgomery, Madeline C; Patel, Rupa R et al. (2018) Improving Insurance and Health Care Systems to Ensure Better Access to Sexually Transmitted Disease Testing and Prevention. Sex Transm Dis 45:283-286
Bharathy, Narendra; Berlow, Noah E; Wang, Eric et al. (2018) The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma. Sci Signal 11:
McGrath-Morrow, Sharon A; Ndeh, Roland; Helmin, Kathryn A et al. (2018) DNA methylation regulates the neonatal CD4+ T-cell response to pneumonia in mice. J Biol Chem 293:11772-11783

Showing the most recent 10 out of 2393 publications