OF SHARED RESOURCE The primary purpose of Animal Resources is to facilitate the specific cancer research program and projects at the Sidney Kimmel Comprehensive Cancer Center (SKCCC). The Department of Research Animal Resources administers all laboratory animal resources and services of the Johns Hopkins University and Medical Institutions. SKCCC Animal Resources, due to its unique programs and goals, is operated as a separate functional unit under the direction of the Associate Provost for Research Animal Resources and the SKCCC and is designed specifically to enable investigator-initiated cancer biologic investigations in animals. The animal facilities and animal care program is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care, International. The SKCCC Animal Resources is in two locations: 1) the ground level of the Bunting-Blaustein Cancer Research Building (CRBI) which contains 8,069 square feet of space, and 2) the basement level of the David S. Koch Cancer Research Building (CRBll) which contains 19,685 square feet of space. Services provided include animal procurement, day-today care and oversight, microbiological monitoring, pathology services, training, maintenance of genetically altered and immunodeficient rodent colonies, consultation on animal model selection, and management of special facilities for the use of hazardous agents. The veterinary medical, microbiological monitoring, and pathology services are performed by the Department of Research Animal Resources on a fee-for-service basis. Cynthia Zahnow, Ph.D, Director, is responsible for the overall planning and direction of Animal Resources. Patricia Karavedas-Matos, is Manager of Animal Resources and is responsible for the day-today direction and operation of the resource. Reqests for continued support for an animal care and use shared resource which provides services to 41 SKCCC investigators. Lay: The SKCCC Animal Resources houses and provides care for mice, rats, rabbits and guinea pigs used in medical research. The facility provides numerous services to investigators to assist them with their research needs. Jointly Managed Shared Resource Current Grant Year Reporting Period: January 1, 2010 to December 31, 2010.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
4P30CA006973-53
Application #
9061608
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2016-05-01
Budget End
2017-04-30
Support Year
53
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Lee, Alice J; Montgomery, Madeline C; Patel, Rupa R et al. (2018) Improving Insurance and Health Care Systems to Ensure Better Access to Sexually Transmitted Disease Testing and Prevention. Sex Transm Dis 45:283-286
Bharathy, Narendra; Berlow, Noah E; Wang, Eric et al. (2018) The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma. Sci Signal 11:
Ambinder, Richard F (2018) A viral protein kinase drug target for tumors? J Clin Invest 128:2197-2198
Huang, Peng; Park, Seyoun; Yan, Rongkai et al. (2018) Added Value of Computer-aided CT Image Features for Early Lung Cancer Diagnosis with Small Pulmonary Nodules: A Matched Case-Control Study. Radiology 286:286-295
Saung, May Tun; Muth, Stephen; Ding, Ding et al. (2018) Targeting myeloid-inflamed tumor with anti-CSF-1R antibody expands CD137+ effector T-cells in the murine model of pancreatic cancer. J Immunother Cancer 6:118
McGrath-Morrow, Sharon A; Ndeh, Roland; Helmin, Kathryn A et al. (2018) DNA methylation regulates the neonatal CD4+ T-cell response to pneumonia in mice. J Biol Chem 293:11772-11783
Connolly, Roisin M; Fackler, Mary Jo; Zhang, Zhe et al. (2018) Tumor and serum DNA methylation in women receiving preoperative chemotherapy with or without vorinostat in TBCRC008. Breast Cancer Res Treat 167:107-116
Ye, I Chae; Fertig, Elana J; DiGiacomo, Josh W et al. (2018) Molecular Portrait of Hypoxia in Breast Cancer: A Prognostic Signature and Novel HIF-Regulated Genes. Mol Cancer Res 16:1889-1901
Kaur, Harsimar B; Guedes, Liana B; Lu, Jiayun et al. (2018) Association of tumor-infiltrating T-cell density with molecular subtype, racial ancestry and clinical outcomes in prostate cancer. Mod Pathol 31:1539-1552
Lu, Yunqi; Hu, Zhongyi; Mangala, Lingegowda S et al. (2018) MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels. Cancer Res 78:64-74

Showing the most recent 10 out of 2393 publications