The primary purpose of the Animal Resources Core is to facilitate cancer relevant animal projects at the Sidney Kimmel Comprehensive Cancer Center (SKCCC). The Johns Hopkins Department of Research Animal Resources oversees all laboratory animal resources and services of The Johns Hopkins University (JHU), including the SKCCC Animal Resources Core. However, due to the unique programs and goals of the SKCCC Animal Resources Core, it is managed as a separate functional unit, under the direction of the Associate Provost for Research Animal Resources and the SKCCC, and is designed specifically to enable investigator- initiated cancer therapeutic investigations in animals. The SKCCC animal care program and facilities are reviewed alongside Research Animal Resources and are fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International. The SKCCC Animal Resources Core is located in two buildings: 1) the ground level of the SKCCC Cancer Research Building I (CRBI), which contains 8,069 net ft2 of space, and 2) the basement level of the SKCCC Cancer Research Building II (CRBII) which contains 29,831 net ft2 of space. Services provided include animal procurement, daily care and oversight, microbiological and sentinel monitoring, veterinary and pathology services, training and assistance with animal handling and technical procedures, maintenance of genetically altered and immunodeficient rodent breeding colonies, cross-fostering of rodent pups, and management of special facilities for the use of BSL2 and BSL3 hazardous agents. The veterinary, microbiological monitoring and pathology services are performed by the Johns Hopkins Department of Research Animal Resources on a fee-for-service basis. Cynthia Zahnow, Ph.D., Core Director, is responsible for the overall management and direction of the SKCCC Animal Resources Core. Sherrie Hawkes is Supervisor of the Animal Resources Core and is responsible for the day-to-day direction and operation of the Core. SKCCC Managed Core Reporting Period: Jan. 1, 2015, to Dec. 31, 2015

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA006973-57
Application #
9944483
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2020-05-01
Budget End
2021-04-30
Support Year
57
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Converse, Paul J; Almeida, Deepak V; Tasneen, Rokeya et al. (2018) Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer. PLoS Negl Trop Dis 12:e0006728
Tolbert, Elliott; Brundage, Michael; Bantug, Elissa et al. (2018) Picture This: Presenting Longitudinal Patient-Reported Outcome Research Study Results to Patients. Med Decis Making 38:994-1005
Paller, Channing J; Zhou, Xian C; Heath, Elisabeth I et al. (2018) Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial. Clin Cancer Res 24:306-315
Fackler, Mary Jo; Sukumar, Saraswati (2018) Quantitation of DNA Methylation by Quantitative Multiplex Methylation-Specific PCR (QM-MSP) Assay. Methods Mol Biol 1708:473-496
Zhang, Jiajia; Quadri, Shafat; Wolfgang, Christopher L et al. (2018) New Development of Biomarkers for Gastrointestinal Cancers: From Neoplastic Cells to Tumor Microenvironment. Biomedicines 6:
Sun, Im-Hong; Oh, Min-Hee; Zhao, Liang et al. (2018) mTOR Complex 1 Signaling Regulates the Generation and Function of Central and Effector Foxp3+ Regulatory T Cells. J Immunol 201:481-492
Newitt, David C; Malyarenko, Dariya; Chenevert, Thomas L et al. (2018) Multisite concordance of apparent diffusion coefficient measurements across the NCI Quantitative Imaging Network. J Med Imaging (Bellingham) 5:011003
Cottrell, T R; Thompson, E D; Forde, P M et al. (2018) Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small-cell lung carcinoma: a proposal for quantitative immune-related pathologic response criteria (irPRC). Ann Oncol 29:1853-1860
Tosoian, Jeffrey J; Guedes, Liana B; Morais, Carlos L et al. (2018) PTEN status assessment in the Johns Hopkins active surveillance cohort. Prostate Cancer Prostatic Dis :
Tran, Phuong T; Meeker, Alan K; Platz, Elizabeth A (2018) Association between statin drug use and peripheral blood leukocyte telomere length in the National Health and Nutrition Examination Survey 1999-2002: a cross-sectional study. Ann Epidemiol 28:529-534

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