The Biostatistics Core provides long-term collaborative support to established programs of research at the Cancer Center, and short-term consulting services. The work of the Core enhances the scientific objectives of the Center?s research programs by providing expertise on study design and statistical analysis. The field of biostatistics is devoted to developing an understanding of the appropriate ways to derive scientific inferences from quantitative data, and to developing methods for achieving this aim. The staff is highly trained in this field and were all recruited after extensive national searches. The Core consists of 19 doctoral-level faculty biostatisticians, assisted by 16 masters-level biostatisticians, 1 bachelor-level biostatistician, and a team of programming staff and administrative staff. The doctoral-level biostatisticians in the Core have broad, collective experience in all of the specialized areas of statistical techniques that are pertinent to contemporary cancer research, including clinical trials methodology, survival analysis, epidemiologic methods, analysis of genomics data, statistical genetics, methods for diagnostic medicine, evidence-based medicine and psychometric methods. Cost recovery is achieved primarily through involvement of the Core members and staff as funded co-investigators on NIH grants. By providing a valid framework for the design, conduct and analysis of scientific studies, the Core contributes to scientific quality and promotes interdisciplinary research. The broad range of services and collaborative work provided by the Biostatistics Core has supported the research of 482 investigators in the past year. During the past grant period the work of the Core has contributed to 2,539 publications of researchers from 9 research programs. For example, the Biostatistics Core developed a method called FACETS to infer copy number alterations from the institution?s IMPACT sequencing assay. FACETS has quickly become part of the standard toolkit of genomic analysis at MSK.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA008748-55
Application #
10084831
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
1997-01-20
Project End
2023-12-31
Budget Start
2021-01-01
Budget End
2021-12-31
Support Year
55
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Parker, Patricia A; Banerjee, Smita C; Matasar, Matthew J et al. (2018) Efficacy of a survivorship-focused consultation versus a time-controlled rehabilitation consultation in patients with lymphoma: A cluster randomized controlled trial. Cancer 124:4567-4576
Chou, Chun; Li, Ming O (2018) Re(de)fining Innate Lymphocyte Lineages in the Face of Cancer. Cancer Immunol Res 6:372-377
Scope, A; Dusza, S W; Pellacani, G et al. (2018) Accuracy of tele-consultation on management decisions of lesions suspect for melanoma using reflectance confocal microscopy as a stand-alone diagnostic tool. J Eur Acad Dermatol Venereol :
Baradaran, Rozbeh; Wang, Chongyuan; Siliciano, Andrew Francis et al. (2018) Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters. Nature 559:580-584
Patel, Sunil V; Yu, David; Elsolh, Basheer et al. (2018) Assessment of Conflicts of Interest in Robotic Surgical Studies: Validating Author's Declarations With the Open Payments Database. Ann Surg 268:86-92
Wolner, Z J; Marghoob, A A; Pulitzer, M P et al. (2018) A case report of disappearing pigmented skin lesions associated with pembrolizumab treatment for metastatic melanoma. Br J Dermatol 178:265-269
Corrias, Giuseppe; Monti, Serena; Mannelli, Lorenzo (2018) Right Upper Quadrant Pain in a 47-Year-Old Woman. Gastroenterology 154:e11-e12
Hu, Zishuo I; Shia, Jinru; Stadler, Zsofia K et al. (2018) Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations. Clin Cancer Res 24:1326-1336
Connors, Joseph M; Jurczak, Wojciech; Straus, David J et al. (2018) Brentuximab Vedotin with Chemotherapy for Stage III or IV Hodgkin's Lymphoma. N Engl J Med 378:331-344
Reznik, Ed; Luna, Augustin; Aksoy, Bülent Arman et al. (2018) A Landscape of Metabolic Variation across Tumor Types. Cell Syst 6:301-313.e3

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