The Biostatistics Core provides long-term collaborative support to established programs of research at the Cancer Center, and short-term consulting services. The work of the Core enhances the scientific objectives of the Center?s research programs by providing expertise on study design and statistical analysis. The field of biostatistics is devoted to developing an understanding of the appropriate ways to derive scientific inferences from quantitative data, and to developing methods for achieving this aim. The staff is highly trained in this field and were all recruited after extensive national searches. The Core consists of 19 doctoral-level faculty biostatisticians, assisted by 16 masters-level biostatisticians, 1 bachelor-level biostatistician, and a team of programming staff and administrative staff. The doctoral-level biostatisticians in the Core have broad, collective experience in all of the specialized areas of statistical techniques that are pertinent to contemporary cancer research, including clinical trials methodology, survival analysis, epidemiologic methods, analysis of genomics data, statistical genetics, methods for diagnostic medicine, evidence-based medicine and psychometric methods. Cost recovery is achieved primarily through involvement of the Core members and staff as funded co-investigators on NIH grants. By providing a valid framework for the design, conduct and analysis of scientific studies, the Core contributes to scientific quality and promotes interdisciplinary research. The broad range of services and collaborative work provided by the Biostatistics Core has supported the research of 482 investigators in the past year. During the past grant period the work of the Core has contributed to 2,539 publications of researchers from 9 research programs. For example, the Biostatistics Core developed a method called FACETS to infer copy number alterations from the institution?s IMPACT sequencing assay. FACETS has quickly become part of the standard toolkit of genomic analysis at MSK.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA008748-55
Application #
10084831
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
1997-01-20
Project End
2023-12-31
Budget Start
2021-01-01
Budget End
2021-12-31
Support Year
55
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Ghasemiesfe, Mehrnaz; Ravi, Divya; Vali, Marzieh et al. (2018) Marijuana Use, Respiratory Symptoms, and Pulmonary Function: A Systematic Review and Meta-analysis. Ann Intern Med 169:106-115
Benedict, Catherine; DuHamel, Katherine; Nelson, Christian J (2018) Reduction in social activities mediates the relationship between diarrhea and distress in rectal/anal cancer survivors. Psychooncology 27:691-694
Gao, Song; Stein, Seth; Petre, Elena N et al. (2018) Micropapillary and/or Solid Histologic Subtype Based on Pre-Treatment Biopsy Predicts Local Recurrence After Thermal Ablation of Lung Adenocarcinoma. Cardiovasc Intervent Radiol 41:253-259
Perrier, Nancy D; Brierley, James D; Tuttle, R Michael (2018) Differentiated and anaplastic thyroid carcinoma: Major changes in the American Joint Committee on Cancer eighth edition cancer staging manual. CA Cancer J Clin 68:55-63
Jee, David; Yang, Jr-Shiuan; Park, Sun-Mi et al. (2018) Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals. Mol Cell 69:265-278.e6
Mirpuri, Sheena; Gill, Pavan; Ocampo, Alex et al. (2018) Discrimination and Health Among Taxi Drivers in New York and Toronto. J Community Health 43:667-672
Jones, Christopher W; Misemer, Benjamin S; Platts-Mills, Timothy F et al. (2018) Primary outcome switching among drug trials with and without principal investigator financial ties to industry: a cross-sectional study. BMJ Open 8:e019831
Horvat, Natally; Ragucci, Monica; Mannelli, Lorenzo (2018) Hepatic Mass in a Patient With Bladder Cancer History. Gastroenterology 154:493-494
Raghunathan, Nirupa Jaya; Benedict, Catherine; Thom, Bridgette et al. (2018) Young Adult Female Cancer Survivors' Concerns About Future Children's Health and Genetic Risk. J Adolesc Young Adult Oncol 7:125-129
Arvold, Nils D; Armstrong, Terri S; Warren, Katherine E et al. (2018) Corticosteroid use endpoints in neuro-oncology: Response Assessment in Neuro-Oncology Working Group. Neuro Oncol 20:897-906

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