The Cancer Center of the Wake Forest University (CCWFU) is a multidisciplinary, interdepartmental cancer research facility. Research is organized into three divisions: 1. Division of Basic Sciences, 2. Division of Clinical Research, 3. Division of Cancer Control. Each is further subdivided into programs. The Division of Basic Sciences is composed of programs of research in Immunology and Molecular Genetics, Pharmacology, Cell Biology and Inflammation, Thrombosis and Experimental Radiation Oncology. The Division of Clinical Research has a major emphasis on technology transfer with introduction of new ideas from laboratory research to be applied in the diagnosis and treatment of cancer. These new leads stem from basic research conducted at the CCWFU, as well as at other cancer centers. Areas of special interest at the CCWFU include research in leukemia and other hematologic malignancies, breast, lung and colon cancer. In addition to clinical research conducted at the Center, a major clinical program is focused on the diffusion and application of new information into community practice through an organization known as the Piedmont Oncology Association (POA). The POA is a consortium of university and community oncologists throughout the 5-state regions of the Piedmont - North and South Carolina, Southern Virginia, Eastern Tennessee, and parts of Georgia. This Cancer Center-sponsored outreach program focuses on collaborative clinical trials and continuing education programs. In addition, the CCWFU brings protocols of a high priority fostered by the NCI and multi- university, national cooperative groups into the community. This approach offers community physicians and their patients the latest in cancer care. The Division of Cancer Control focuses on public education that will increase an awareness of cancer and will offer preventive measures and interventions for early detection. The Epidemiology Program will provide surveillance of cancer incidence in the region served by the Cancer Center in order to alert the faculty to the needs in education, prevention, and early detection. The CCWFU supports high technology core laboratories which facilitate cancer research. These include Tissue Culture, Electron Microscopy, Flow Cytometry, GC/MS, Pharmacology, NMR, Hybridoma, Oligonucleotide Synthesis Laboratory, Membrane Lipid Laboratory, and Protein Sequencing. Education in cancer is offered as a formal oncology curriculum to medical students, cancer research training for basic scientists at both the pre- and postdoctoral level and continuing education for physicians and nurses. The CCWFU has established a Cancer Patient Support Program which offers psychological supportive care to patients and their families and conducts research as to how this care might be optimized. Areas of future growth will include Molecular Genetics, Pharmacology, Immunology, Cell Biology and marrow transplantation.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA012197-18
Application #
3101281
Study Section
Cancer Center Support Review Committee (CCS)
Project Start
1976-03-01
Project End
1994-01-31
Budget Start
1990-02-01
Budget End
1991-01-31
Support Year
18
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Su, Weijun; Hong, Lixin; Xu, Xin et al. (2018) miR-30 disrupts senescence and promotes cancer by targeting both p16INK4A and DNA damage pathways. Oncogene 37:5618-5632
Miller Jr, David P; Denizard-Thompson, Nancy; Weaver, Kathryn E et al. (2018) Effect of a Digital Health Intervention on Receipt of Colorectal Cancer Screening in Vulnerable Patients: A Randomized Controlled Trial. Ann Intern Med 168:550-557
Rimkus, Tadas K; Carpenter, Richard L; Sirkisoon, Sherona et al. (2018) Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44. Cancer Res 78:2589-2600
Bonin, Keith; Smelser, Amanda; Moreno, Naike Salvador et al. (2018) Structured illumination to spatially map chromatin motions. J Biomed Opt 23:1-8
Rogers, LeAnn C; Davis, Ryan R; Said, Naveen et al. (2018) Blocking LPA-dependent signaling increases ovarian cancer cell death in response to chemotherapy. Redox Biol 15:380-386
Maggiore, Ronald J; Callahan, Kathryn E; Tooze, Janet A et al. (2018) Geriatrics fellowship training and the role of geriatricians in older adult cancer care: A survey of geriatrics fellowship directors. Gerontol Geriatr Educ 39:170-182
Melvin, Ryan L; Xiao, Jiajie; Godwin, Ryan C et al. (2018) Visualizing correlated motion with HDBSCAN clustering. Protein Sci 27:62-75
Faig, Jennifer; Haughton, Michael; Taylor, Richard C et al. (2018) Retrospective Analysis of Cisplatin Nephrotoxicity in Patients With Head and Neck Cancer Receiving Outpatient Treatment With Concurrent High-dose Cisplatin and Radiotherapy. Am J Clin Oncol 41:432-440
Nelson, Kimberly J; Perkins, Arden; Van Swearingen, Amanda E D et al. (2018) Experimentally Dissecting the Origins of Peroxiredoxin Catalysis. Antioxid Redox Signal 28:521-536
Swanner, Jessica; Singh, Ravi (2018) Synthesis, Purification, Characterization, and Imaging of Cy3-Functionalized Fluorescent Silver Nanoparticles in 2D and 3D Tumor Models. Methods Mol Biol 1790:209-218

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