Abstract

The Media Preparation Core Facility provides CCR members and their laboratories with immediate access to a wide variety of culture media and sterile solutions that are critical for their research programs. This includes both standard formulations of bacterial and tissue culture media as well as custom-made yeast medias. The Media Preparation Core Facility also provides specialized media to the Transgenic Animal Core Facility. The media facility is highly reliable, producing a comprehensive panel of reagents that are of outstanding quality and, in many cases, not available from commercial sources. A significant fraction of the facilities operating costs are recovered by per-item chargebacks. The centralization of these services allows the CCR to minimize staff costs and space requirements while maximizing efficiency and cost-effectiveness. Price comparisons with commercial sources (for those items that are commercially available) show that the resulting costs to CCR Investigators are highly competitive. Moreover, outsourcing of these services would preclude us from providing the non-commercially available media that are critical for several of our members. Therefore, the Media Preparation Core Facility is a key resource for CCR researchers and represents excellent value for the CCSG.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014051-37
Application #
7668624
Study Section
Project Start
Project End
Budget Start
2008-05-01
Budget End
2009-04-30
Support Year
37
Fiscal Year
2008
Total Cost
$179,047
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Ramadi, Khalil B; Dagdeviren, Canan; Spencer, Kevin C et al. (2018) Focal, remote-controlled, chronic chemical modulation of brain microstructures. Proc Natl Acad Sci U S A 115:7254-7259
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Sabari, Benjamin R; Dall'Agnese, Alessandra; Boija, Ann et al. (2018) Coactivator condensation at super-enhancers links phase separation and gene control. Science 361:
Knouse, Kristin A; Lopez, Kristina E; Bachofner, Marc et al. (2018) Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture. Cell 175:200-211.e13
Fiedler, Eleanor R C; Bhutkar, Arjun; Lawler, Emily et al. (2018) In vivo RNAi screening identifies Pafah1b3 as a target for combination therapy with TKIs in BCR-ABL1 + BCP-ALL. Blood Adv 2:1229-1242
Clancy-Thompson, Eleanor; Devlin, Christine A; Tyler, Paul M et al. (2018) Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+ T Cell-Effector Responses. Cancer Immunol Res 6:1524-1536
Miller, Eric A; Baniya, Subha; Osorio, Daniel et al. (2018) Paper-based diagnostics in the antigen-depletion regime: High-density immobilization of rcSso7d-cellulose-binding domain fusion proteins for efficient target capture. Biosens Bioelectron 102:456-463
Sullivan, Lucas B; Luengo, Alba; Danai, Laura V et al. (2018) Aspartate is an endogenous metabolic limitation for tumour growth. Nat Cell Biol 20:782-788
Filbin, Mariella G; Tirosh, Itay; Hovestadt, Volker et al. (2018) Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science 360:331-335
Lannagan, Tamsin R M; Lee, Young K; Wang, Tongtong et al. (2018) Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis. Gut :

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