Administrative: The Cancer Center Support Grant is administered by the Koch Institute for Integrative Cancer Research at MIT under the direction of Ms. Cynthia Quense, the Assistant Director for Administration. The Koch Institute has a centralized administrative system to support the Members within the Koch Institute building. This structure allows for specialization within areas while also providing administrative staff that are very familiar with the individualized needs of Members and their respective laboratories. The central administration team (known as the Headquarters Office (HQ)) provides support to the Koch Institute in the following key areas: Finance, pre and post award of research and discretionary funds; Human Resources; Operations (Facilities & Building Maintenance); Program and Grant Administration; Reception/Office Management, and; Koch Institute Events including Symposium, Retreat and Special Seminars. Coordination and oversight is also provided to research administration areas including Environment, Health, and Safety (EHS), financial oversight of Core Facilities and Faculty Administrative Assistants. In addition, the HQ team provides CCSG-specific administrative support to the Members outside of the building in the areas of: Core Facilities operations and billing, Membership, Program support, Pilot Projects, other internal funding mechanisms, funding announcements, cancer-related fellowships; and, full administrative support for Center grants including CCNE, PSOC, ICBP and the Ludwig Center. Ms. Quense was hired in January 2007. She holds an MPA from Harvard and has an extensive background in non-profit and academic financial administration and administrative management. Ms. Quense reports directly to Dr. Jacks, Director of the Koch Institute, and is part of the CCSG Senior Leadership and the Executive Committee. Ms. Quense also interfaces with MIT administrative officials to ensure a cohesive relationship between the Koch Institute and the Institute. She also serves as liaison with the Howard Hughes Medical Institute. There are 20 FTEs on the HQ team. This has grown from 16 in the last renewal linked to the expansion to the Koch Institute building. Of the 20 HQ staff, support for 4 FTEs is requested from the CCSG Administrative budget. The remaining staff are covered by Institutional or other research funds. Senior Leadership: The Senior Leadership of the Koch Institute consists of the Director, Dr. Tyler Jacks, the two Associate Directors, Drs. Jacqueline Lees and K. Dane Wittrup, and the Assistant Director for Administration, Ms. Cynthia Quense. The Senior Leadership meets regularly with the other CCSG Program leaders (Drs. Amon, Bhatia, Hynes, Langer, Sharp, and Yaffe ? who is also the Director of the Koch Institute Clinical Investigator Program) as the Koch Institute Executive Committee (EC) to discuss planning issues including Membership, faculty and staff hiring, junior faculty mentoring, Core Facilities, space issues, policies, and use of Developmental Funds. All costs of Senior Leadership are covered through Institutional support.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014051-45
Application #
9149826
Study Section
Subcommittee I - Transistion to Independence (NCI)
Program Officer
Shafik, Hasnaa
Project Start
Project End
Budget Start
2016-05-01
Budget End
2017-04-30
Support Year
45
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
Guen, Vincent J; Edvardson, Simon; Fraenkel, Nitay D et al. (2018) A homozygous deleterious CDK10 mutation in a patient with agenesis of corpus callosum, retinopathy, and deafness. Am J Med Genet A 176:92-98
Murphy, Patrick A; Butty, Vincent L; Boutz, Paul L et al. (2018) Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow. Elife 7:
Khan, Omar F; Kowalski, Piotr S; Doloff, Joshua C et al. (2018) Endothelial siRNA delivery in nonhuman primates using ionizable low-molecular weight polymeric nanoparticles. Sci Adv 4:eaar8409
Woolston, Benjamin M; Roth, Timothy; Kohale, Ishwar et al. (2018) Development of a formaldehyde biosensor with application to synthetic methylotrophy. Biotechnol Bioeng 115:206-215
Huang, Hsin-Ho; Qian, Yili; Del Vecchio, Domitilla (2018) A quasi-integral controller for adaptation of genetic modules to variable ribosome demand. Nat Commun 9:5415
GuimarĂ£es, Pedro P G; Gaglione, Stephanie; Sewastianik, Tomasz et al. (2018) Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy. ACS Nano 12:912-931
Moynihan, Kelly D; Holden, Rebecca L; Mehta, Naveen K et al. (2018) Enhancement of Peptide Vaccine Immunogenicity by Increasing Lymphatic Drainage and Boosting Serum Stability. Cancer Immunol Res 6:1025-1038
Nath, Samir R; Yu, Zhigang; Gipson, Theresa A et al. (2018) Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. J Clin Invest 128:3630-3641
Kimmerling, Robert J; Prakadan, Sanjay M; Gupta, Alejandro J et al. (2018) Linking single-cell measurements of mass, growth rate, and gene expression. Genome Biol 19:207
Rothenberg, Daniel A; Taliaferro, J Matthew; Huber, Sabrina M et al. (2018) A Proteomics Approach to Profiling the Temporal Translational Response to Stress and Growth. iScience 9:367-381

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