Developmental Funds have had a high scientific impact during the project period. Developmental Funds were used to support the external recruitment of nine New Investigators who have brought scientific expertise in high priority areas, the development of a new Circulating Tumor Cell Shared Resource that provides unique technology and exceptional scientific expertise in this burgeoning area, and the funding of a pilot project that has contributed to our growing Adolescent and Young Adult Program. These accomplishments were funded by a total of $545,000 in Developmental Funds during the four year project period (approximately $130,000 per year): $425,000 for New Investigators, $50,000 for Pilot Projects and $70,000 for Developing Shared Resources. In this application, we request a budget of $450,000 per year for Developmental Funds. Of this amount, $200,000 will be allocated for the recruitment of New Investigators in high priority research areas, $200,000 for the development of a new Bioinformatics Shared Resource, and $50,000 for novel pilot projects with the potential to secure external funding. Developmental Funds will be critical to growing our research base and increasing collaborative research in targeted areas. The focus of annual pilot project program, priorities for New Investigators support, and plans for Shared Resources will continue to be developed with input from Senior and Program Leaders and guided by advice from our External Advisory Board.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014089-45
Application #
9838163
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2019-12-01
Budget End
2020-11-30
Support Year
45
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Zhou, Beiyun; Flodby, Per; Luo, Jiao et al. (2018) Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis. J Clin Invest 128:970-984
Nguyen, Lisa; Wang, Zheng; Chowdhury, Adnan Y et al. (2018) Functional compensation between hematopoietic stem cell clones in vivo. EMBO Rep 19:
Jadvar, Hossein; Chen, Xiaoyuan; Cai, Weibo et al. (2018) Radiotheranostics in Cancer Diagnosis and Management. Radiology 286:388-400
Tokunaga, Ryuma; Zhang, Wu; Naseem, Madiha et al. (2018) CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation - A target for novel cancer therapy. Cancer Treat Rev 63:40-47
Khanova, Elena; Wu, Raymond; Wang, Wen et al. (2018) Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients. Hepatology 67:1737-1753
McSkane, Michelle; Stintzing, Sebastian; Heinemann, Volker et al. (2018) Association Between Height and Clinical Outcome in Metastatic Colorectal Cancer Patients Enrolled Onto a Randomized Phase 3 Clinical Trial: Data From the FIRE-3 Study. Clin Colorectal Cancer 17:215-222.e3
Tokunaga, Ryuma; Cao, Shu; Naseem, Madiha et al. (2018) Prognostic Effect of Adenosine-related Genetic Variants in Metastatic Colorectal Cancer Treated With Bevacizumab-based Chemotherapy. Clin Colorectal Cancer :
Brunette, Laurie L; Mhawech-Fauceglia, Paulette Y; Ji, Lingyun et al. (2018) Validity and prognostic significance of sperm protein 17 as a tumor biomarker for epithelial ovarian cancer: a retrospective study. BMC Cancer 18:970
Poulard, Coralie; Baulu, Estelle; Lee, Brian H et al. (2018) Increasing G9a automethylation sensitizes B acute lymphoblastic leukemia cells to glucocorticoid-induced death. Cell Death Dis 9:1038
Lang, Julie E; Brownson, Kirstyn E (2018) ASO Author Reflections: The Whole Transcriptome Landscape of Circulating Tumor Cells in Nonmetastatic Breast Cancer. Ann Surg Oncol :

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