Abstract

Developmental funds have played an important role in the development of the Cancer Center, particularly in recruiting new investigators and in establishing new Shared Resources. During the current funding period developmental funds were instrumental in the recruitment of three new investigators and in the development of two new Shared Resources (Advanced Biophotonics and Gene Transfer, Targeting and Therapeutics/Viral Vectors). We propose to continue our recruitment efforts to strengthen the scientific programs of the Cancer Center

Public Health Relevance

The research mission of the Cancer Center is to understand the fundamental aspects of biology related to cancer. Developmental funds will provide support for new investigators, enable the exploration of new research directions, new collaborations and support the translation of basic research into therapies for cancer.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014195-43
Application #
8984280
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2015-12-01
Budget End
2016-11-30
Support Year
43
Fiscal Year
2016
Total Cost
Indirect Cost

  Institution

Name
Salk Institute for Biological Studies
Department
Type
DUNS #
078731668
City
La Jolla
State
CA
Country
United States
Zip Code
92037

  Publications

Benegiamo, Giorgia; Mure, Ludovic S; Erikson, Galina et al. (2018) The RNA-Binding Protein NONO Coordinates Hepatic Adaptation to Feeding. Cell Metab 27:404-418.e7
Sulli, Gabriele; Rommel, Amy; Wang, Xiaojie et al. (2018) Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence. Nature 553:351-355
Yoon, Young-Sil; Tsai, Wen-Wei; Van de Velde, Sam et al. (2018) cAMP-inducible coactivator CRTC3 attenuates brown adipose tissue thermogenesis. Proc Natl Acad Sci U S A 115:E5289-E5297
Xia, Yifeng; Zhan, Cheng; Feng, Mingxiang et al. (2018) Targeting CREB Pathway Suppresses Small Cell Lung Cancer. Mol Cancer Res 16:825-832
Stern, S; Santos, R; Marchetto, M C et al. (2018) Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium. Mol Psychiatry 23:1453-1465
Limpert, Allison S; Lambert, Lester J; Bakas, Nicole A et al. (2018) Autophagy in Cancer: Regulation by Small Molecules. Trends Pharmacol Sci 39:1021-1032
Mure, Ludovic S; Le, Hiep D; Benegiamo, Giorgia et al. (2018) Diurnal transcriptome atlas of a primate across major neural and peripheral tissues. Science 359:
Lu, Zhimin; Hunter, Tony (2018) Metabolic Kinases Moonlighting as Protein Kinases. Trends Biochem Sci 43:301-310
Wang, Zheng; Wu, Catherine; Aslanian, Aaron et al. (2018) Defective RNA polymerase III is negatively regulated by the SUMO-Ubiquitin-Cdc48 pathway. Elife 7:
Fan, Weiwei; He, Nanhai; Lin, Chun Shi et al. (2018) ERR? Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1?/?-Deficient Muscle. Cell Rep 22:2521-2529

Showing the most recent 10 out of 457 publications