Abstract

The University of Wisconsin Clinical Cancer Center is a multidisciplinary, interdepartmental organization that facilitates high quality clinical and laboratory research training and cancer care. The Center Faculty, utilizing Center space and facilities, excels in laboratory and clinical research exploring cancer problems. Through its investigation of human cancer, it serves residents of Wisconsin and adjoining areas of Iowa and Illinois by providing optimal cancer care and innovative clinical trials. The Center offers unique opportunities to train cancer specialists in laboratory, clinical and statistical disciplines. Its outreach programs involve other cancer care and research institutions in the state as well as the public and professionals in the area. The Cancer Center Sup;port Grant to the UW Clinical Cancer Center aids in progressing towards the long term goal, reduction of the incidence, mortality and morbidity of human cancer. The broad objectives of the center are: 1. To undertake innovative laboratory and clinical research probing biologic problems in cancer. 2. To facilitate clinical applications of findings from research. 3. To improve cancer care through clinical trials. 4. To train specialists in cancer related fields. 5. To educate students, professionals and the public in Wisconsin about cancer.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014520-19
Application #
3101432
Study Section
Cancer Center Support Review Committee (CCS)
Project Start
1976-01-01
Project End
1993-03-31
Budget Start
1991-04-01
Budget End
1992-03-31
Support Year
19
Fiscal Year
1991
Total Cost
Indirect Cost

  Institution

Name
University of Wisconsin Madison
Department
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715

  Publications

Liu, Bai; Jones, Monica; Kong, Lin et al. (2018) Evaluation of the biological activities of the IL-15 superagonist complex, ALT-803, following intravenous versus subcutaneous administration in murine models. Cytokine 107:105-112
Yu, Deyang; Yang, Shany E; Miller, Blake R et al. (2018) Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms. FASEB J 32:3471-3482
Carroll, Molly J; Fogg, Kaitlin C; Patel, Harin A et al. (2018) Alternatively-Activated Macrophages Upregulate Mesothelial Expression of P-Selectin to Enhance Adhesion of Ovarian Cancer Cells. Cancer Res 78:3560-3573
Ehlerding, Emily B; Grodzinski, Piotr; Cai, Weibo et al. (2018) Big Potential from Small Agents: Nanoparticles for Imaging-Based Companion Diagnostics. ACS Nano 12:2106-2121
Park, Linda; Schwei, R J; Xiong, P et al. (2018) Addressing Cultural Determinants of Health for Latino and Hmong Patients with Limited English Proficiency: Practical Strategies to Reduce Health Disparities. J Racial Ethn Health Disparities 5:536-544
Ehlerding, Emily B; Lan, Xiaoli; Cai, Weibo (2018) ""Albumin Hitchhiking"" with an Evans Blue Analog for Cancer Theranostics. Theranostics 8:812-814
Morris, Zachary S; Guy, Emily I; Werner, Lauryn R et al. (2018) Tumor-Specific Inhibition of In Situ Vaccination by Distant Untreated Tumor Sites. Cancer Immunol Res 6:825-834
Yu, Bo; Goel, Shreya; Ni, Dalong et al. (2018) Reassembly of 89 Zr-Labeled Cancer Cell Membranes into Multicompartment Membrane-Derived Liposomes for PET-Trackable Tumor-Targeted Theranostics. Adv Mater 30:e1704934
England, Christopher G; Jiang, Dawei; Ehlerding, Emily B et al. (2018) 89Zr-labeled nivolumab for imaging of T-cell infiltration in a humanized murine model of lung cancer. Eur J Nucl Med Mol Imaging 45:110-120
Rutter, Carolyn M; Kim, Jane J; Meester, Reinier G S et al. (2018) Effect of Time to Diagnostic Testing for Breast, Cervical, and Colorectal Cancer Screening Abnormalities on Screening Efficacy: A Modeling Study. Cancer Epidemiol Biomarkers Prev 27:158-164

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