The Scientific Instrumentation Facility and its personnel provide three types of services related tolaboratory equipment and facilities to UWCCC investigators. First, it maintains an array of commonlyrequired scientific equipment for shared use at the Clinical Science Center (CSC) in close proximity tothe clinical facilities and the McArdle Laboratory, in close proximity to the nucleus of basic sciencedepartments. The shared equipment includes centrifuges, scintillation counters, phosphorimagers,fluorimagers, Class III biosafety cabinets, ice machines, and water purification units. The facilityprovides support for the purchase of these types of shared equipment, installation, and preventivemaintenance and repair; it also coordinates repair services for all investigator-owned commonlaboratory instruments. Second, it affords access to and training in the use of a BL-3 level containmentfacility located in the McArdle Laboratory that enables UWCCC members to work safely with extremehuman pathogens, such as the Human Immunodeficiency Virus or Hepatitis B Virus. Finally, SIFfacilitates the relocation of personnel or laboratory equipment, coordinates all remodeling projects, andestablishes customized laboratory facilities for new faculty by coordinating with the University PhysicalPlant and Engineering Craft services. This shared resource maintains an inventory of UWCCCequipment and usage, and facilitates the enforcement of UWCCC security, safety, and spacemanagement policies.

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National Cancer Institute (NCI)
Center Core Grants (P30)
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Subcommittee G - Education (NCI)
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University of Wisconsin Madison
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Voter, Andrew F; Killoran, Michael P; Ananiev, Gene E et al. (2018) A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility. SLAS Discov 23:94-101
Thomas, Sydney P; Hoang, Trish T; Ressler, Valerie T et al. (2018) Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor. RNA 24:1018-1027
Barault, Ludovic; Amatu, Alessio; Siravegna, Giulia et al. (2018) Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer. Gut 67:1995-2005
Long, Yin; Wei, Hao; Li, Jun et al. (2018) Effective Wound Healing Enabled by Discrete Alternative Electric Fields from Wearable Nanogenerators. ACS Nano :
Forsberg, Matthew H; Das, Amritava; Saha, Krishanu et al. (2018) The potential of CAR T therapy for relapsed or refractory pediatric and young adult B-cell ALL. Ther Clin Risk Manag 14:1573-1584
Ni, Dalong; Jiang, Dawei; Ehlerding, Emily B et al. (2018) Radiolabeling Silica-Based Nanoparticles via Coordination Chemistry: Basic Principles, Strategies, and Applications. Acc Chem Res 51:778-788
Burnside, Elizabeth S; Vulkan, Daniel; Blanks, Roger G et al. (2018) Association between Screening Mammography Recall Rate and Interval Cancers in the UK Breast Cancer Service Screening Program: A Cohort Study. Radiology 288:47-54
Johnson, Brian P; Vitek, Ross A; Geiger, Peter G et al. (2018) Vital ex vivo tissue labeling and pathology-guided micropunching to characterize cellular heterogeneity in the tissue microenvironment. Biotechniques 64:13-19
Elezaby, Mai; Li, Geng; Bhargavan-Chatfield, Mythreyi et al. (2018) ACR BI-RADS Assessment Category 4 Subdivisions in Diagnostic Mammography: Utilization and Outcomes in the National Mammography Database. Radiology 287:416-422
Tanimura, Nobuyuki; Liao, Ruiqi; Wilson, Gary M et al. (2018) GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism. Dev Cell 46:581-594.e4

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