The primary goal of the Cancer Informatics Shared Resource (CISR) is to provide UW Carbone Cancer Center (UWCCC) members with access to technologies, services and scientific consultation to aid in their mission to prevent, diagnose and treat cancer. The CISR works to provide members with modern and efficient informatics, including advancements in bioinformatics, clinical informatics, image analysis and computational science in a cost-effective manner. To accomplish this, the CISR offers technological resources and services to members including an informatics infrastructure for collecting, storing, analyzing and sharing of data;support for systems integration;and the development of specialized tools and/or the implementation of third-party tools. In addition, the CISR offers intellectual resources and services by providing members access to a wide range of skills and expertise in biomedical informatics to improve data collection, interpreting research data sets using existing analysis methods and technologies and developing new methodology when needed. The need for biomedical informatics in cancer research has only increased in the period since our last renewal. Therefore, UWCCC is working to develop a more robust cancer-managed informatics infrastructure and partnering with the UW-Madison CTSA-funded Institute for Clinical and Translational Research to significantly improve its capacity to develop the complex, and costly, services and resources that benefit biomedical research. New opportunities for this collaboration include the unification of UWCCC and ICTR Clinical Research Management System, integration with the UW Health Electronic Medical Record and interface with the UW Data Warehouse.

Public Health Relevance

The goal of the Cancer Informatics Shared Resource (CISR) is to help UWCCC researchers in their mission to prevent, diagnose and treat cancer. The success of cancer research has become increasingly dependent on the analysis of large amounts of research data. To this end, the CISR provides researchers with the tools, expertise and technical resources to manage data in an efficient and cost-effective manner to further their research objectives.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014520-40
Application #
8762773
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
40
Fiscal Year
2014
Total Cost
$280,389
Indirect Cost
$59,443
Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Xu, Cheng; Chen, Feng; Valdovinos, Hector F et al. (2018) Bacteria-like mesoporous silica-coated gold nanorods for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined therapy. Biomaterials 165:56-65
Wargowski, Ellen; Johnson, Laura E; Eickhoff, Jens C et al. (2018) Prime-boost vaccination targeting prostatic acid phosphatase (PAP) in patients with metastatic castration-resistant prostate cancer (mCRPC) using Sipuleucel-T and a DNA vaccine. J Immunother Cancer 6:21
Bednarz, Bryan; Grudzinski, Joseph; Marsh, Ian et al. (2018) Murine-specific Internal Dosimetry for Preclinical Investigations of Imaging and Therapeutic Agents. Health Phys 114:450-459
Romero-Masters, James C; Ohashi, Makoto; Djavadian, Reza et al. (2018) An EBNA3C-deleted Epstein-Barr virus (EBV) mutant causes B-cell lymphomas with delayed onset in a cord blood-humanized mouse model. PLoS Pathog 14:e1007221
van den Broek, Jeroen J; van Ravesteyn, Nicolien T; Mandelblatt, Jeanne S et al. (2018) Comparing CISNET Breast Cancer Incidence and Mortality Predictions to Observed Clinical Trial Results of Mammography Screening from Ages 40 to 49. Med Decis Making 38:140S-150S
Lu, Zhanping; Hong, Courtney C; Kong, Guangyao et al. (2018) Polycomb Group Protein YY1 Is an Essential Regulator of Hematopoietic Stem Cell Quiescence. Cell Rep 22:1545-1559
Shea, Michael P; O'Leary, Kathleen A; Fakhraldeen, Saja A et al. (2018) Antiestrogen Therapy Increases Plasticity and Cancer Stemness of Prolactin-Induced ER?+ Mammary Carcinomas. Cancer Res 78:1672-1684
Schrager, Sarina; Burnside, Elizabeth (2018) Breast Cancer Screening in Primary Care: A Call for Development and Validation of Patient-Oriented Shared Decision-Making Tools. J Womens Health (Larchmt) :
Liu, Bai; Jones, Monica; Kong, Lin et al. (2018) Evaluation of the biological activities of the IL-15 superagonist complex, ALT-803, following intravenous versus subcutaneous administration in murine models. Cytokine 107:105-112
Yu, Deyang; Yang, Shany E; Miller, Blake R et al. (2018) Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms. FASEB J 32:3471-3482

Showing the most recent 10 out of 1528 publications