The primary goal of the Cancer Informatics Shared Resource (CISR) is to provide UW Carbone Cancer Center (UWCCC) members with access to technologies, services and scientific consultation to aid in their mission to prevent, diagnose and treat cancer. The CISR works to provide members with modern and efficient informatics, including advancements in bioinformatics, clinical informatics, image analysis and computational science in a cost-effective manner. To accomplish this, the CISR offers technological resources and services to members including an informatics infrastructure for collecting, storing, analyzing and sharing of data;support for systems integration;and the development of specialized tools and/or the implementation of third-party tools. In addition, the CISR offers intellectual resources and services by providing members access to a wide range of skills and expertise in biomedical informatics to improve data collection, interpreting research data sets using existing analysis methods and technologies and developing new methodology when needed. The need for biomedical informatics in cancer research has only increased in the period since our last renewal. Therefore, UWCCC is working to develop a more robust cancer-managed informatics infrastructure and partnering with the UW-Madison CTSA-funded Institute for Clinical and Translational Research to significantly improve its capacity to develop the complex, and costly, services and resources that benefit biomedical research. New opportunities for this collaboration include the unification of UWCCC and ICTR Clinical Research Management System, integration with the UW Health Electronic Medical Record and interface with the UW Data Warehouse.

Public Health Relevance

The goal of the Cancer Informatics Shared Resource (CISR) is to help UWCCC researchers in their mission to prevent, diagnose and treat cancer. The success of cancer research has become increasingly dependent on the analysis of large amounts of research data. To this end, the CISR provides researchers with the tools, expertise and technical resources to manage data in an efficient and cost-effective manner to further their research objectives.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014520-40
Application #
8762773
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
40
Fiscal Year
2014
Total Cost
$280,389
Indirect Cost
$59,443
Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Wu, Yirong; Fan, Jun; Peissig, Peggy et al. (2018) Quantifying predictive capability of electronic health records for the most harmful breast cancer. Proc SPIE Int Soc Opt Eng 10577:
Fu, Anqi; Oberholtzer, Sydney M; Bagheri-Fam, Stefan et al. (2018) Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries. PLoS Genet 14:e1007488
Ni, Dalong; Jiang, Dawei; Kutyreff, Christopher J et al. (2018) Molybdenum-based nanoclusters act as antioxidants and ameliorate acute kidney injury in mice. Nat Commun 9:5421
Huynh, Mailee; Pak, Chorom; Markovina, Stephanie et al. (2018) Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-?B activity and increases drug resistance in multiple myeloma. J Biol Chem 293:2452-2465
Farrell, Emily; Armstrong, Annie E; Grimes, Adrian C et al. (2018) Transcriptome Analysis of Cardiac Hypertrophic Growth in MYBPC3-Null Mice Suggests Early Responders in Hypertrophic Remodeling. Front Physiol 9:1442
Net, Jose M; Whitman, Gary J; Morris, Elizabteh et al. (2018) Relationships Between Human-Extracted MRI Tumor Phenotypes of Breast Cancer and Clinical Prognostic Indicators Including Receptor Status and Molecular Subtype. Curr Probl Diagn Radiol :
Jiang, Dawei; Ge, Zhilei; Im, Hyung-Jun et al. (2018) DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury. Nat Biomed Eng 2:865-877
Seok, Seung-Hyeon; Ma, Zhi-Xiong; Feltenberger, John B et al. (2018) Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR). J Biol Chem 293:1994-2005
Chapelin, Fanny; Capitini, Christian M; Ahrens, Eric T (2018) Fluorine-19 MRI for detection and quantification of immune cell therapy for cancer. J Immunother Cancer 6:105
Ni, Dalong; Ferreira, Carolina A; Barnhart, Todd E et al. (2018) Magnetic Targeting of Nanotheranostics Enhances Cerenkov Radiation-Induced Photodynamic Therapy. J Am Chem Soc 140:14971-14979

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