The primary goal of the Cancer Informatics Shared Resource (CISR) is to provide UW Carbone Cancer Center (UWCCC) members with access to technologies, services and scientific consultation to aid in their mission to prevent, diagnose and treat cancer. The CISR works to provide members with modern and efficient informatics, including advancements in bioinformatics, clinical informatics, image analysis and computational science in a cost-effective manner. To accomplish this, the CISR offers technological resources and services to members including an informatics infrastructure for collecting, storing, analyzing and sharing of data; support for systems integration; and the development of specialized tools and/or the implementation of third-party tools. In addition, the CISR offers intellectual resources and services by providing members access to a wide range of skills and expertise in biomedical informatics to improve data collection, interpreting research data sets using existing analysis methods and technologies and developing new methodology when needed. The need for biomedical informatics in cancer research has only increased in the period since our last renewal. Therefore, UWCCC is working to develop a more robust cancer-managed informatics infrastructure and partnering with the UW-Madison CTSA-funded Institute for Clinical and Translational Research to significantly improve its capacity to develop the complex, and costly, services and resources that benefit biomedical research. New opportunities for this collaboration include the unification of UWCCC and ICTR Clinical Research Management System, integration with the UW Health Electronic Medical Record and interface with the UW Data Warehouse.

Public Health Relevance

The goal of the Cancer Informatics Shared Resource (CISR) is to help UWCCC researchers in their mission to prevent, diagnose and treat cancer. The success of cancer research has become increasingly dependent on the analysis of large amounts of research data. To this end, the CISR provides researchers with the tools, expertise and technical resources to manage data in an efficient and cost-effective manner to further their research objectives.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
4P30CA014520-42
Application #
9067939
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2016-04-01
Budget End
2017-03-31
Support Year
42
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Esbona, Karla; Yi, Yanyao; Saha, Sandeep et al. (2018) The Presence of Cyclooxygenase 2, Tumor-Associated Macrophages, and Collagen Alignment as Prognostic Markers for Invasive Breast Carcinoma Patients. Am J Pathol 188:559-573
Hernández-Santos, Nydiaris; Wiesner, Darin L; Fites, J Scott et al. (2018) Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection. Cell Host Microbe 23:511-522.e5
van Ravesteyn, Nicolien T; van den Broek, Jeroen J; Li, Xiaoxue et al. (2018) Modeling Ductal Carcinoma In Situ (DCIS): An Overview of CISNET Model Approaches. Med Decis Making 38:126S-139S
Robins, H Ian; Nguyen, HuyTram N; Field, Aaron et al. (2018) Molecular Evolution of a Glioblastoma Controlled With Tumor Treating Fields and Concomitant Temozolomide. Front Oncol 8:451
Pezzi, Hannah M; Niles, David J; Schehr, Jennifer L et al. (2018) Integration of Magnetic Bead-Based Cell Selection into Complex Isolations. ACS Omega 3:3908-3917
Alagoz, Oguzhan; Ergun, Mehmet Ali; Cevik, Mucahit et al. (2018) The University of Wisconsin Breast Cancer Epidemiology Simulation Model: An Update. Med Decis Making 38:99S-111S
Lyu, Zhigang; Kang, Lei; Buuh, Zakey Yusuf et al. (2018) A Switchable Site-Specific Antibody Conjugate. ACS Chem Biol 13:958-964
Hardin, Heather; Helein, Holly; Meyer, Kristy et al. (2018) Thyroid cancer stem-like cell exosomes: regulation of EMT via transfer of lncRNAs. Lab Invest 98:1133-1142
Xu, Cheng; Chen, Feng; Valdovinos, Hector F et al. (2018) Bacteria-like mesoporous silica-coated gold nanorods for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined therapy. Biomaterials 165:56-65
Wargowski, Ellen; Johnson, Laura E; Eickhoff, Jens C et al. (2018) Prime-boost vaccination targeting prostatic acid phosphatase (PAP) in patients with metastatic castration-resistant prostate cancer (mCRPC) using Sipuleucel-T and a DNA vaccine. J Immunother Cancer 6:21

Showing the most recent 10 out of 1528 publications