The University of Wisconsin Carbone Cancer Center (UWCCC) seeks continued funding for years 44-48 in pursuit of its mission to dramatically reduce the burden of cancer within and beyond its catchment. The UWCCC, which is a matrix center within the University of Wisconsin School of Medicine and Public Health (SMPH), is composed of 198 faculty members from 38 departments and 8 schools of the University of Wisconsin-Madison (UW). Our members pursue cancer care, research and education through 6 scientific programs (Human Cancer Virology, Cancer Genetic and Epigenetic Mechanisms, Tumor Microenvironment, Imaging and Radiation Sciences, Developmental Therapeutics, and Cancer Prevention and Control) supported by 10 Shared Resources. During the period 2012-2016, our members published 3324 cancer relevant manuscripts (with 66% collaborative) and were supported by $63.7M (Direct) peer-reviewed cancer relevant funding and $16.6M (Direct) non peer-reviewed funding (as of December 31, 2016). The UWCCC will accomplish this mission through nurturing a supportive cancer community, reliable infrastructure, and efficient resources. The UWCCC worked to decrease the burden of cancer in our catchment and beyond through prioritized research areas (e.g. innovative therapies and biomarkers, cancer imaging and expanded population-based cancer research), enhanced research platforms (e.g. improved clinical research infrastructure and shared resources), increased efforts to build mission-related philanthropy and expanded local to global partnerships.

Public Health Relevance

The University of Wisconsin Carbone Cancer Center (UWCCC), which is a matrix center within the University of Wisconsin School of Medicine and Public Health (SMPH), seeks to dramatically reduce the burden of cancer within and beyond our catchment. Specifically, the UWCCC will do this by decreasing cancer incidence and mortality among populations within our catchment area and beyond, including our minority and underserved populations. We will facilitate pursuit of this goal through partnerships with other health delivery systems and state and community agencies for dissemination of evidence-based findings. The UWCCC will accomplish the aforementioned goals through nurturing a supportive cancer community, reliable infrastructure and efficient resources. The UWCCC has started to decrease the burden of cancer in our catchment and beyond through prioritized research areas (e.g. innovative therapies and biomarkers, cancer imaging and expanded population- based cancer research), enhanced research platforms (e.g. improved clinical research infrastructure and shared resources), increased efforts to build mission-related philanthropy and expanded local to global partnerships.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014520-46
Application #
9922999
Study Section
Subcommittee I - Transistion to Independence (NCI)
Program Officer
Shafik, Hasnaa
Project Start
1997-04-25
Project End
2023-03-31
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
46
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Zhang, Fan; Braun, Doug R; Ananiev, Gene E et al. (2018) Biemamides A-E, Inhibitors of the TGF-? Pathway That Block the Epithelial to Mesenchymal Transition. Org Lett 20:5529-5532
Deming, Dustin A (2018) Tailoring the colorectal cancer disease assessment to the treatment strategy. Gut 67:996-997
Ferreira, Carolina A; Ni, Dalong; Rosenkrans, Zachary T et al. (2018) Scavenging of reactive oxygen and nitrogen species with nanomaterials. Nano Res 11:4955-4984
Ehlerding, Emily B; Ferreira, Carolina A; Aluicio-Sarduy, Eduardo et al. (2018) 86/90Y-Based Theranostics Targeting Angiogenesis in a Murine Breast Cancer Model. Mol Pharm 15:2606-2613
Ehlerding, Emily B; Lan, Xiaoli; Cai, Weibo (2018) Predicting PD-1/PD-L1 status in bladder cancer with 18F-FDG PET? Eur J Nucl Med Mol Imaging :
Tomko, Lucas A; Hill, Ryan C; Barrett, Alexander et al. (2018) Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma. Sci Rep 8:12941
Saghiri, Mohammad Ali; Asatourian, Armen; Sheibani, Nader (2018) Angiogenesis and the prevention of alveolar osteitis: a review study. J Korean Assoc Oral Maxillofac Surg 44:93-102
Pandhi, Nancy; Kraft, Sally; Berkson, Stephanie et al. (2018) Developing primary care teams prepared to improve quality: a mixed-methods evaluation and lessons learned from implementing a microsystems approach. BMC Health Serv Res 18:847
Aluicio-Sarduy, Eduardo; Ellison, Paul A; Barnhart, Todd E et al. (2018) PET radiometals for antibody labeling. J Labelled Comp Radiopharm 61:636-651
Slosarek, Erin L; Schuh, Amber L; Pustova, Iryna et al. (2018) Pathogenic TFG Mutations Underlying Hereditary Spastic Paraplegia Impair Secretory Protein Trafficking and Axon Fasciculation. Cell Rep 24:2248-2260

Showing the most recent 10 out of 1528 publications