The long-term goal of UWCCC Community Outreach and Engagement activities is to decrease cancer incidence and mortality among populations within our catchment area and beyond, including our minority and underserved populations. We will achieve this goal through partnerships with other health delivery systems and state and community agencies for dissemination of evidence-based findings.
Our specific aims are: (1) to understand our catchment area population through improved data collection and analysis, with a special emphasis on identifying disparities, (2) to engage our catchment area and state in clinical trials that are relevant to and appropriate for our populations, including underserved populations, and (3) to work with and serve our community organizations, affiliated health systems, and regional networks in the dissemination and implementation of evidence-based interventions and health policy recommendations, particularly for underserved populations. To accomplish these aims, the UWCCC engages researchers to build the evidence base for interventions to benefit our catchment area and beyond, as well as integrate what we learn from our catchment area into future research. Our UWCCC engagement activities and scientific programs have focused on areas of significant cancer burden within our 36- county catchment, including lung, breast, colorectal, and prostate cancer. Focus areas include lung and breast cancer among African Americans, cervical cancer among Hispanics, lung and colorectal cancer among American Indians, and delays in diagnosis among our rural residents. Colonoscopy screening rates are low and smoking rates are high among low income residents, while alcohol consumption is high. Through leveraging our extensive networks for research and outreach, we will engage our catchment area residents in clinical trials and the broad- based activities that have been shown to improve the health of, and in particular for, our disadvantaged populations. We specifically expand engagement of our catchment area participants in clinical trials facilitated through the National Clinical Trials Network, the Veterans Administration Hospitals and Clinics, the Precision Medicine Molecular Tumor Board, and the UW Center for Tobacco Research and Intervention. Disparities in clinical trial recruitment will be targeted by assessing and addressing barriers to clinical trials participation, improving recruitment materials, and developing targeted and culturally appropriate outreach. Our broad-based outreach activities include dissemination and implementation of evidence-based interventions and health policy recommendations for tobacco cessation, HPV vaccine uptake, colorectal cancer screening, and alcohol use. We will also continue to expand our Cancer Clear and Simple curriculum developed specifically for rural areas. Overall, we expect that these activities will continue to have a substantial positive impact on reducing the burden of cancer within our catchment area.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014520-46
Application #
9923045
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
46
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Voter, Andrew F; Killoran, Michael P; Ananiev, Gene E et al. (2018) A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility. SLAS Discov 23:94-101
Thomas, Sydney P; Hoang, Trish T; Ressler, Valerie T et al. (2018) Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor. RNA 24:1018-1027
Barault, Ludovic; Amatu, Alessio; Siravegna, Giulia et al. (2018) Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer. Gut 67:1995-2005
Long, Yin; Wei, Hao; Li, Jun et al. (2018) Effective Wound Healing Enabled by Discrete Alternative Electric Fields from Wearable Nanogenerators. ACS Nano :
Forsberg, Matthew H; Das, Amritava; Saha, Krishanu et al. (2018) The potential of CAR T therapy for relapsed or refractory pediatric and young adult B-cell ALL. Ther Clin Risk Manag 14:1573-1584
Ni, Dalong; Jiang, Dawei; Ehlerding, Emily B et al. (2018) Radiolabeling Silica-Based Nanoparticles via Coordination Chemistry: Basic Principles, Strategies, and Applications. Acc Chem Res 51:778-788
Burnside, Elizabeth S; Vulkan, Daniel; Blanks, Roger G et al. (2018) Association between Screening Mammography Recall Rate and Interval Cancers in the UK Breast Cancer Service Screening Program: A Cohort Study. Radiology 288:47-54
Johnson, Brian P; Vitek, Ross A; Geiger, Peter G et al. (2018) Vital ex vivo tissue labeling and pathology-guided micropunching to characterize cellular heterogeneity in the tissue microenvironment. Biotechniques 64:13-19
Elezaby, Mai; Li, Geng; Bhargavan-Chatfield, Mythreyi et al. (2018) ACR BI-RADS Assessment Category 4 Subdivisions in Diagnostic Mammography: Utilization and Outcomes in the National Mammography Database. Radiology 287:416-422
Tanimura, Nobuyuki; Liao, Ruiqi; Wilson, Gary M et al. (2018) GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism. Dev Cell 46:581-594.e4

Showing the most recent 10 out of 1528 publications