The Scientific Visualization and Image Analysis (SVIA) Core plays an important role in the UCCRC;its services help to promote collaborations that allow imaging to be used by a number of other programs in the UCRRC. The Core provides three essential services: a high performance computer cluster, a large data storage resource, and software to facilitate the development of databases. In 2007, the computation capabilities of the Core will be upgraded using funds from a recently awarded Shared Instrumentation Grant from the NIH. The new system will have 128 CPUs and 14 TBytes of storage. The Core facilitates the development of databases of patient data by providing a means to collect deidentified patient records, including image data. Since the image is collected in such a way that patient identifiers are removed, researchers do not need to obtain patient consent, and their research is HIPAA compliant. Without this service, collecting patient images would be extremely difficult and timeconsuming. Nearly 4000 patient cases (679 GBytes) were collected in this way. All of these users are conducting research on computer-aided diagnosis, but the Core also supports research on image reconstruction, MR imaging and spectroscopy, electron paramagnetic imaging, and receiver-operating characteristic (ROC) analysis. While most users of the SVIA Core are from the Advanced Imaging Program, the use of the Core facilitates collaborations with members of other Programs, such as the Cancer Risk and Prevention Program. The SVIA Core's future plans include supporting the expansion of the Advanced Imaging Program to promote collaboration between experts in medical imaging and members in other programs. One way this will be done is to create a list of software developed by members of the Advanced Imaging Program that is available to UCCRC members. The goal is to have non-imaging experts team up with members of the Advanced Imaging Program to apply or modify existing software to solve or help solve problems in the basic biological sciences or in clinical medicine.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014599-35
Application #
8105364
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2010-04-01
Budget End
2011-03-31
Support Year
35
Fiscal Year
2010
Total Cost
$103,596
Indirect Cost
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Zeineddine, Hussein A; Girard, Romuald; Saadat, Laleh et al. (2018) Phenotypic characterization of murine models of cerebral cavernous malformations. Lab Invest :
Kane, Melissa; Deiss, Felicity; Chervonsky, Alexander et al. (2018) A Single Locus Controls Interferon Gamma-Independent Antiretroviral Neutralizing Antibody Responses. J Virol 92:
Xiao, Annie; Crosby, Jennie; Malin, Martha et al. (2018) Single-institution report of setup margins of voluntary deep-inspiration breath-hold (DIBH) whole breast radiotherapy implemented with real-time surface imaging. J Appl Clin Med Phys 19:205-213
Gamazon, Eric R; Trendowski, Matthew R; Wen, Yujia et al. (2018) Gene and MicroRNA Perturbations of Cellular Response to Pemetrexed Implicate Biological Networks and Enable Imputation of Response in Lung Adenocarcinoma. Sci Rep 8:733
Girard, Romuald; Zeineddine, Hussein A; Koskimäki, Janne et al. (2018) Plasma Biomarkers of Inflammation and Angiogenesis Predict Cerebral Cavernous Malformation Symptomatic Hemorrhage or Lesional Growth. Circ Res 122:1716-1721
Day, Kasey J; Casler, Jason C; Glick, Benjamin S (2018) Budding Yeast Has a Minimal Endomembrane System. Dev Cell 44:56-72.e4
Pu, Jinyue; Kentala, Kaitlin; Dickinson, Bryan C (2018) Multidimensional Control of Cas9 by Evolved RNA Polymerase-Based Biosensors. ACS Chem Biol 13:431-437
Pectasides, Eirini; Stachler, Matthew D; Derks, Sarah et al. (2018) Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma. Cancer Discov 8:37-48
Liu, Hongtao; Zha, Yuanyuan; Choudhury, Noura et al. (2018) WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia. Exp Hematol Oncol 7:1
Nageeb, Shaheen; Vu, Milkie; Malik, Sana et al. (2018) Adapting a religious health fatalism measure for use in Muslim populations. PLoS One 13:e0206898

Showing the most recent 10 out of 668 publications