The 2007 NCI Review of the UCCCC CCSG was a catalyst for our own institutional in-depth review, followed by a multi-faceted strategic planning process, which has fundamentally and substantially enhanced the UCCCC structure and strengthened Its position within the University. Our strategic planning and evaluation relies on formal internal and external advisory structures and groups. Internal advisory groups include: the Executive Committee (EC), the Cancer Advisory Committee (CAC), the Internal Advisory Committee (lAC), Program Leaders meetings, and the Core Development Working Group (CDWG). In addition, UCCCC senior leaders play a key role in the Dean's Clinical Cancer Program Strategic Growth Committee. External advisory mechanisms include annual External Advisory Committee (EAC) meetings and smaller targeted """"""""mini EACs"""""""" in high priority areas, which provide substantial guidance to the UCCCC leadership with respect to Program and Core development, overall structure, and future directions. These Committees and activities, together with annual UCCCC Program Retreats, targeted strategic planning meetings and retreats, and targeted joint program retreats, have led to significant refocusing of the Research Programs (refocusing and better integration of Cancer Prevention and Control, and Advanced Imaging Programs), enhancement and expansion ofthe Core Facilities (Including consolidation and expansion ofthe imaging cores, development of a new Epidemiology Research and Recruitment Core), strategic recruitment (45 new researchers), and enhanced Interdisciplinary collaboration. A formal Strategic Plan was prepared, organized under the following three major initiatives;1) the Personalized Cancer Care Consortium (PCCC);2) the Center for Cancer Prevention and Population Medicine;and 3) the Program in Cancer Survivorship, Cancer Economics, and Outcomes. Over the next grant cycle, we plan to use this well-established set of internal and external mechanisms to implement the UCCCC's strategic vision, identify strengths, weaknesses and opportunities, and review Center progress.
Planning and evaluation activities are critical to the success of the UCCCC. The mechanisms described above provide the structure within which we review our Programs and Cores to ensure state-of-the art research, enhance intra- and inter-programmatic collaborations, and identify opportunities for continued growth and development. These activities also serve as an important opportunity to engage the Institutional leadership in both creating an institutionally-based cancer-related vision and, supporting the UCCCC In its leadership role to realize this vision.
|Luke, Jason J; Lemons, Jeffrey M; Karrison, Theodore G et al. (2018) Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors. J Clin Oncol 36:1611-1618|
|Wang, Amy Y; Weiner, Howard; Green, Margaret et al. (2018) A phase I study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia. J Hematol Oncol 11:4|
|Sample, Ashley; He, Yu-Ying (2018) Mechanisms and prevention of UV-induced melanoma. Photodermatol Photoimmunol Photomed 34:13-24|
|Jeong, Choongwon; Witonsky, David B; Basnyat, Buddha et al. (2018) Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. PLoS Genet 14:e1007650|
|Wang, Xin; Wu, Xingye; Zhang, Zhonglin et al. (2018) Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway. Sci Rep 8:17914|
|Brown, Hailey M; Biering, Scott B; Zhu, Allen et al. (2018) Demarcation of Viral Shelters Results in Destruction by Membranolytic GTPases: Antiviral Function of Autophagy Proteins and Interferon-Inducible GTPases. Bioessays 40:e1700231|
|Karrison, Theodore; Kocherginsky, Masha (2018) Restricted mean survival time: Does covariate adjustment improve precision in randomized clinical trials? Clin Trials 15:178-188|
|An, Ningfei; Khan, Saira; Imgruet, Molly K et al. (2018) Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS. Blood 131:2682-2697|
|Trujillo, Jonathan A; Sweis, Randy F; Bao, Riyue et al. (2018) T Cell-Inflamed versus Non-T Cell-Inflamed Tumors: A Conceptual Framework for Cancer Immunotherapy Drug Development and Combination Therapy Selection. Cancer Immunol Res 6:990-1000|
|Zeng, Zongyue; Huang, Bo; Huang, Shifeng et al. (2018) The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs. Genes Dis 5:62-74|
Showing the most recent 10 out of 668 publications