The 2007 NCI Review of the UCCCC CCSG was a catalyst for our own institutional in-depth review, followed by a multi-faceted strategic planning process, which has fundamentally and substantially enhanced the UCCCC structure and strengthened Its position within the University. Our strategic planning and evaluation relies on formal internal and external advisory structures and groups. Internal advisory groups include: the Executive Committee (EC), the Cancer Advisory Committee (CAC), the Internal Advisory Committee (lAC), Program Leaders meetings, and the Core Development Working Group (CDWG). In addition, UCCCC senior leaders play a key role in the Dean's Clinical Cancer Program Strategic Growth Committee. External advisory mechanisms include annual External Advisory Committee (EAC) meetings and smaller targeted """"""""mini EACs"""""""" in high priority areas, which provide substantial guidance to the UCCCC leadership with respect to Program and Core development, overall structure, and future directions. These Committees and activities, together with annual UCCCC Program Retreats, targeted strategic planning meetings and retreats, and targeted joint program retreats, have led to significant refocusing of the Research Programs (refocusing and better integration of Cancer Prevention and Control, and Advanced Imaging Programs), enhancement and expansion ofthe Core Facilities (Including consolidation and expansion ofthe imaging cores, development of a new Epidemiology Research and Recruitment Core), strategic recruitment (45 new researchers), and enhanced Interdisciplinary collaboration. A formal Strategic Plan was prepared, organized under the following three major initiatives;1) the Personalized Cancer Care Consortium (PCCC);2) the Center for Cancer Prevention and Population Medicine;and 3) the Program in Cancer Survivorship, Cancer Economics, and Outcomes. Over the next grant cycle, we plan to use this well-established set of internal and external mechanisms to implement the UCCCC's strategic vision, identify strengths, weaknesses and opportunities, and review Center progress.

Public Health Relevance

Planning and evaluation activities are critical to the success of the UCCCC. The mechanisms described above provide the structure within which we review our Programs and Cores to ensure state-of-the art research, enhance intra- and inter-programmatic collaborations, and identify opportunities for continued growth and development. These activities also serve as an important opportunity to engage the Institutional leadership in both creating an institutionally-based cancer-related vision and, supporting the UCCCC In its leadership role to realize this vision.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014599-39
Application #
8744846
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
39
Fiscal Year
2014
Total Cost
$24,470
Indirect Cost
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Trujillo, Jonathan A; Sweis, Randy F; Bao, Riyue et al. (2018) T Cell-Inflamed versus Non-T Cell-Inflamed Tumors: A Conceptual Framework for Cancer Immunotherapy Drug Development and Combination Therapy Selection. Cancer Immunol Res 6:990-1000
Zeng, Zongyue; Huang, Bo; Huang, Shifeng et al. (2018) The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs. Genes Dis 5:62-74
Lee, Ji-Hye; Park, Beom Seok; Han, Kang R et al. (2018) Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication. Front Microbiol 9:1466
Cheng, Jason X; Chen, Li; Li, Yuan et al. (2018) RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun 9:1163
Johnson, Marianna B; Hoffmann, Joscelyn N; You, Hannah M et al. (2018) Psychosocial Stress Exposure Disrupts Mammary Gland Development. J Mammary Gland Biol Neoplasia 23:59-73
Sweis, Randy F; Zha, Yuanyuan; Pass, Lomax et al. (2018) Pseudoprogression manifesting as recurrent ascites with anti-PD-1 immunotherapy in urothelial bladder cancer. J Immunother Cancer 6:24
Kathayat, Rahul S; Cao, Yang; Elvira, Pablo D et al. (2018) Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes. Nat Commun 9:334
Liu, Jun; Eckert, Mark A; Harada, Bryan T et al. (2018) m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol 20:1074-1083
Bhanvadia, Raj R; VanOpstall, Calvin; Brechka, Hannah et al. (2018) MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease. Clin Cancer Res 24:3668-3680
Wood, Kevin; Byron, Elizabeth; Janisch, Linda et al. (2018) Capecitabine and Celecoxib as a Promising Therapy for Thymic Neoplasms. Am J Clin Oncol 41:963-966

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