The University of Chicago Comprehensive Cancer Center (UCCCC) is a formal academic unit within the Division of the Biological Sciences (BSD), and the main body within the University to plan, facilitate, and promote research, education, community outreach, and health information services all focused on cancer. The Director has Department Chair status, and serves as a standing member of the BSD Research Advisory Committee and the Clinical Cancer Strategic Growth Committee, the major policy-making bodies of the BSD regarding research and cancer clinical programs. The Associate Director for Administration has the status of Departmental Executive Administration (EA) and attends all BSD-level and Medical Center (UCMC) Operations meetings (meetings of the EAs and senior BSD administrators), thereby representing the UCCCC interests at the institutional level. The Director has control of the budgets of the CCSG, the ACS Institutional Research Grant, and all large, multi-investigator grants administered by the UCCCC, e.g., POI grants. Breast Cancer SPORE as well as all UCCCC endowment income, gift income, discretionary funds, and operational budget provided by the BSD. The Director has authority over UCCCC membership and appointments, direct and shared authority over shared resources, and direct authority over 5,000 sq ft of office space, 5,000 sq ft of dry lab space and 23,000 sq ft of wet lab space. Under the leadership of Dr. Marcy List, Associate Director for Administration, the UCCCC Administrative Unit is responsible for oversight and management of those activities that support the mission of the Center and the research of its members. The Administrative Unit includes: Finances and Human Resources (Director + 3 FTEs) responsible for management of $7.5M in federal and non-federal grants and contracts and $10M in Philanthropy, and HR issues for 50 UCCCC employees;Informatics (Director + 5 FTEs) responsible for all informatics and database support for UCCCC administrative groups, the CCTO and UCCCC investigators as well as coordinating UCCCC IT activities with those of the BSD and UCMC, and supporting the UCCCC Website;grant support staff (2 FTEs) responsible for all non-financial pre- and post-award for multi-investigators grants (noted above), program development support (planning and evaluation activities, coordination of activities related to membership and recruitment, seminars and meeting coordination).

Public Health Relevance

The Administrative Unit of the UCCCC provides the support and infrastructure to researchers and clinicians to collaborate in fulfilling the mission of the UCCCC. UCCCC Administration plays a key role in facilitating inter and intraprogrammafic interactions, managing pilot funding opportunities, new core development, and the recruitment of new faculty. The Administration also plays a critical role in clinical research operations by providing the basic informatics infrastructure and working with investigators to assess evolving needs.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Chicago
United States
Zip Code
Trujillo, Jonathan A; Sweis, Randy F; Bao, Riyue et al. (2018) T Cell-Inflamed versus Non-T Cell-Inflamed Tumors: A Conceptual Framework for Cancer Immunotherapy Drug Development and Combination Therapy Selection. Cancer Immunol Res 6:990-1000
Zeng, Zongyue; Huang, Bo; Huang, Shifeng et al. (2018) The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs. Genes Dis 5:62-74
Lee, Ji-Hye; Park, Beom Seok; Han, Kang R et al. (2018) Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication. Front Microbiol 9:1466
Cheng, Jason X; Chen, Li; Li, Yuan et al. (2018) RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun 9:1163
Johnson, Marianna B; Hoffmann, Joscelyn N; You, Hannah M et al. (2018) Psychosocial Stress Exposure Disrupts Mammary Gland Development. J Mammary Gland Biol Neoplasia 23:59-73
Sweis, Randy F; Zha, Yuanyuan; Pass, Lomax et al. (2018) Pseudoprogression manifesting as recurrent ascites with anti-PD-1 immunotherapy in urothelial bladder cancer. J Immunother Cancer 6:24
Kathayat, Rahul S; Cao, Yang; Elvira, Pablo D et al. (2018) Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes. Nat Commun 9:334
Liu, Jun; Eckert, Mark A; Harada, Bryan T et al. (2018) m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol 20:1074-1083
Bhanvadia, Raj R; VanOpstall, Calvin; Brechka, Hannah et al. (2018) MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease. Clin Cancer Res 24:3668-3680
Wood, Kevin; Byron, Elizabeth; Janisch, Linda et al. (2018) Capecitabine and Celecoxib as a Promising Therapy for Thymic Neoplasms. Am J Clin Oncol 41:963-966

Showing the most recent 10 out of 668 publications