The University of Chicago Comprehensive Cancer Center (UCCCC) is a formal academic unit within the Division of the Biological Sciences (BSD), and the main body within the University to plan, facilitate, and promote research, education, community outreach, and health information services all focused on cancer. The Director has Department Chair status, and serves as a standing member of the BSD Research Advisory Committee and the Clinical Cancer Strategic Growth Committee, the major policy-making bodies of the BSD regarding research and cancer clinical programs. The Associate Director for Administration has the status of Departmental Executive Administration (EA) and attends all BSD-level and Medical Center (UCMC) Operations meetings (meetings of the EAs and senior BSD administrators), thereby representing the UCCCC interests at the institutional level. The Director has control of the budgets of the CCSG, the ACS Institutional Research Grant, and all large, multi-investigator grants administered by the UCCCC, e.g., POI grants. Breast Cancer SPORE as well as all UCCCC endowment income, gift income, discretionary funds, and operational budget provided by the BSD. The Director has authority over UCCCC membership and appointments, direct and shared authority over shared resources, and direct authority over 5,000 sq ft of office space, 5,000 sq ft of dry lab space and 23,000 sq ft of wet lab space. Under the leadership of Dr. Marcy List, Associate Director for Administration, the UCCCC Administrative Unit is responsible for oversight and management of those activities that support the mission of the Center and the research of its members. The Administrative Unit includes: Finances and Human Resources (Director + 3 FTEs) responsible for management of $7.5M in federal and non-federal grants and contracts and $10M in Philanthropy, and HR issues for 50 UCCCC employees; Informatics (Director + 5 FTEs) responsible for all informatics and database support for UCCCC administrative groups, the CCTO and UCCCC investigators as well as coordinating UCCCC IT activities with those of the BSD and UCMC, and supporting the UCCCC Website; grant support staff (2 FTEs) responsible for all non-financial pre- and post-award for multi-investigators grants (noted above), program development support (planning and evaluation activities, coordination of activities related to membership and recruitment, seminars and meeting coordination).

Public Health Relevance

The Administrative Unit of the UCCCC provides the support and infrastructure to researchers and clinicians to collaborate in fulfilling the mission of the UCCCC. UCCCC Administration plays a key role in facilitating inter and intraprogrammafic interactions, managing pilot funding opportunities, new core development, and the recruitment of new faculty. The Administration also plays a critical role in clinical research operations by providing the basic informatics infrastructure and working with investigators to assess evolving needs.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Chicago
United States
Zip Code
Hope, C Matthew; Webber, Jemma L; Tokamov, Sherzod A et al. (2018) Tuned polymerization of the transcription factor Yan limits off-DNA sequestration to confer context-specific repression. Elife 7:
Wu, Chengyue; Pineda, Federico; Hormuth 2nd, David A et al. (2018) Quantitative analysis of vascular properties derived from ultrafast DCE-MRI to discriminate malignant and benign breast tumors. Magn Reson Med :
Wong, Gabrielle S; Zhou, Jin; Liu, Jie Bin et al. (2018) Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition. Nat Med 24:968-977
Ni, Kaiyuan; Lan, Guangxu; Chan, Christina et al. (2018) Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy. Nat Commun 9:2351
Meisel, Marlies; Hinterleitner, Reinhard; Pacis, Alain et al. (2018) Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host. Nature 557:580-584
Webber, Jemma L; Zhang, Jie; Massey, Alex et al. (2018) Collaborative repressive action of the antagonistic ETS transcription factors Pointed and Yan fine-tunes gene expression to confer robustness in Drosophila. Development 145:
Wei, Jiangbo; Liu, Fange; Lu, Zhike et al. (2018) Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm. Mol Cell 71:973-985.e5
Boisclair Lachance, Jean-Fran├žois; Webber, Jemma L; Hong, Lu et al. (2018) Cooperative recruitment of Yan via a high-affinity ETS supersite organizes repression to confer specificity and robustness to cardiac cell fate specification. Genes Dev 32:389-401
Szmulewitz, Russell Z; Peer, Cody J; Ibraheem, Abiola et al. (2018) Prospective International Randomized Phase II Study of Low-Dose Abiraterone With Food Versus Standard Dose Abiraterone In Castration-Resistant Prostate Cancer. J Clin Oncol 36:1389-1395
Maron, Steven B; Alpert, Lindsay; Kwak, Heewon A et al. (2018) Targeted Therapies for Targeted Populations: Anti-EGFR Treatment for EGFR-Amplified Gastroesophageal Adenocarcinoma. Cancer Discov 8:696-713

Showing the most recent 10 out of 668 publications